LOC127893949 (OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr20:57227205-57227708) - Rat Genome Database

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Gene: LOC127893949 (OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr20:57227205-57227708) Homo sapiens
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Symbol: LOC127893949
Name: OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr20:57227205-57227708
RGD ID: 155781880
Description: This genomic region includes an enhancer that was validated by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in primed human embryonic stem cells, where it associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac histone modification. This locus also includes an accessible chromatin subregion that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382058,652,042 - 58,652,652 (+)NCBIGRCh38GRCh38hg38GRCh38
T2T-CHM13v2.02060,434,106 - 60,434,717 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119   PMID:35858748  


Genomics

Variants

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Variants in LOC127893949
5 total Variants

Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127893949 COSMIC
GTEx LOC127893949 GTEx
Human Proteome Map LOC127893949 Human Proteome Map
NCBI Gene LOC127893949 ENTREZGENE