LOC127888507 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79875237-79876133) - Rat Genome Database

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Gene: LOC127888507 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79875237-79876133) Homo sapiens
Analyze
Symbol: LOC127888507
Name: H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:79875237-79876133
RGD ID: 155769640
Description: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in naive human embryonic stem cells, where it is marked by the H3K27ac and H3K4me1 histone modifications. This locus also includes an accessible chromatin subregion that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,917,361 - 81,918,257 (+)NCBIGRCh38GRCh38hg38GRCh38
T2T-CHM13v2.01782,784,521 - 82,785,417 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119   PMID:35858748  


Genomics

Variants

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Variants in LOC127888507
2 total Variants

Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127888507 COSMIC
GTEx LOC127888507 GTEx
Human Proteome Map LOC127888507 Human Proteome Map
NCBI Gene LOC127888507 ENTREZGENE