LOC127267058 (H3K27ac hESC enhancer GRCh37_chr1:3817068-3817637) - Rat Genome Database

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Gene: LOC127267058 (H3K27ac hESC enhancer GRCh37_chr1:3817068-3817637) Homo sapiens
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Symbol: LOC127267058
Name: H3K27ac hESC enhancer GRCh37_chr1:3817068-3817637
RGD ID: 155640022
Description: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in primed human embryonic stem cells, where it is marked by the H3K27ac histone modification. This locus also includes an accessible chromatin subregion that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813,900,504 - 3,901,073 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713,817,068 - 3,817,637 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.013,412,408 - 3,412,977 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


PMID:30033119   PMID:35858748  



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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
RefSeq Transcripts NG_088933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BX005110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles



Database
Acc Id
Source(s)
COSMIC LOC127267058 COSMIC
GTEx LOC127267058 GTEx
Human Proteome Map LOC127267058 Human Proteome Map
NCBI Gene LOC127267058 ENTREZGENE