LOC127267660 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16533787-16534760) - Rat Genome Database

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Gene: LOC127267660 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16533787-16534760) Homo sapiens
Analyze
Symbol: LOC127267660
Name: H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16533787-16534760
RGD ID: 155638379
Description: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,207,292 - 16,208,265 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,533,787 - 16,534,760 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.0115,648,626 - 15,649,595 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119  


Genomics

Variants

.
Variants in LOC127267660
14 total Variants

QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407326612GWAS975588_Hserum gamma-glutamyl transferase measurement QTL GWAS975588 (human)4e-130serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)11620776016207761Human
407164594GWAS813570_Haspartate aminotransferase measurement QTL GWAS813570 (human)9e-23aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)11620776016207761Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407310587GWAS959563_Hlow density lipoprotein cholesterol measurement QTL GWAS959563 (human)4e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11620776016207761Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407174985GWAS823961_Hserum alanine aminotransferase measurement QTL GWAS823961 (human)2e-23serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)11620776016207761Human
407164986GWAS813962_Hapolipoprotein B measurement QTL GWAS813962 (human)6e-10apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)11620776016207761Human
407176138GWAS825114_Hserum albumin measurement QTL GWAS825114 (human)1e-11serum albumin measurementserum albumin level (CMO:0000550)11620776016207761Human
407322808GWAS971784_Hsex hormone-binding globulin measurement QTL GWAS971784 (human)2e-12sex hormone-binding globulin measurement11620776016207761Human


Expression

RNA-SEQ Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127267660 COSMIC
GTEx LOC127267660 GTEx
Human Proteome Map LOC127267660 Human Proteome Map
NCBI Gene LOC127267660 ENTREZGENE