LOC127267990 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21958265-21959233) - Rat Genome Database

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Gene: LOC127267990 (H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21958265-21959233) Homo sapiens
Analyze
Symbol: LOC127267990
Name: H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21958265-21959233
RGD ID: 155635023
Description: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
Type: biological-region
RefSeq Status: REVIEWED
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38121,631,772 - 21,632,740 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37121,958,265 - 21,959,233 (+)NCBIGRCh37GRCh37hg19GRCh37
T2T-CHM13v2.0121,455,674 - 21,456,642 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30033119  


Genomics

Variants

.
Variants in LOC127267990
1 total Variants

QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406897035GWAS546011_Hsmoking initiation QTL GWAS546011 (human)1e-12smoking initiation12163224621632247Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
406973372GWAS622348_Hsmoking initiation QTL GWAS622348 (human)9e-14smoking initiation12163224621632247Human


Expression

RNA-SEQ Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC127267990 COSMIC
GTEx LOC127267990 GTEx
Human Proteome Map LOC127267990 Human Proteome Map
NCBI Gene LOC127267990 ENTREZGENE