Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Paqr5 | Mouse | 1,2-dichloroethane | affects expression | EXP | | 6480464 | ethylene dichloride affects the expression of PAQR5 mRNA | CTD | PMID:28960355 | Paqr5 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PAQR5 mRNA | CTD | PMID:22206623 | Paqr5 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PAQR5 mRNA | CTD | PMID:32109520 | Paqr5 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PAQR5 mRNA | CTD | PMID:33956508 | Paqr5 | Mouse | 2-hydroxypropanoic acid | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PAQR5 mRNA | CTD | PMID:30851411 | Paqr5 | Mouse | 2-palmitoylglycerol | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of PAQR5 mRNA | CTD | PMID:37199045 | Paqr5 | Mouse | 3-chloropropane-1,2-diol | increases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of PAQR5 protein | CTD | PMID:34915118 | Paqr5 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Paqr5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PAQR5 mRNA | CTD | PMID:36041667 | Paqr5 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PAQR5 mRNA | CTD | PMID:24780913 and PMID:25825206 | Paqr5 | Mouse | 6-propyl-2-thiouracil | multiple interactions | EXP | | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PAQR5 mRNA | CTD | PMID:36706583 | Paqr5 | Mouse | 8-Br-cAMP | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PAQR5 mRNA | CTD | PMID:20147733 | Paqr5 | Mouse | acrylamide | increases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of PAQR5 mRNA | CTD | PMID:28959563 | Paqr5 | Mouse | aflatoxin B1 | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PAQR5 mRNA | CTD | PMID:22100608 | Paqr5 | Mouse | amphetamine | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of PAQR5 mRNA | CTD | PMID:30779732 | Paqr5 | Mouse | atrazine | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Atrazine results in increased expression of PAQR5 mRNA | CTD | PMID:22378314 | Paqr5 | Mouse | azathioprine | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Azathioprine results in increased expression of PAQR5 mRNA | CTD | PMID:22623647 | Paqr5 | Mouse | benzo[a]pyrene | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PAQR5 mRNA | CTD | PMID:20106945 more ... | Paqr5 | Mouse | benzo[a]pyrene | increases methylation | ISO | PAQR5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PAQR5 promoter | CTD | PMID:27901495 | Paqr5 | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20018196 | Paqr5 | Mouse | beta-lapachone | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of PAQR5 mRNA | CTD | PMID:38218311 | Paqr5 | Mouse | bisphenol A | increases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PAQR5 mRNA | CTD | PMID:30816183 and PMID:32528016 | Paqr5 | Mouse | bisphenol A | multiple interactions | ISO | Paqr5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PAQR5 mRNA | CTD | PMID:36041667 | Paqr5 | Mouse | bisphenol A | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PAQR5 gene | CTD | PMID:31601247 | Paqr5 | Mouse | bisphenol A | decreases methylation | ISO | PAQR5 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PAQR5 gene | CTD | PMID:31601247 | Paqr5 | Mouse | bisphenol A | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PAQR5 mRNA | CTD | PMID:34947998 | Paqr5 | Mouse | bisphenol F | multiple interactions | ISO | Paqr5 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PAQR5 mRNA | CTD | PMID:36041667 | Paqr5 | Mouse | calcitriol | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of PAQR5 mRNA | CTD | PMID:16002434 and PMID:26485663 | Paqr5 | Mouse | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of PAQR5 mRNA | CTD | PMID:37019170 | Paqr5 | Mouse | copper(II) chloride | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | cupric chloride results in increased expression of PAQR5 mRNA | CTD | PMID:38568856 | Paqr5 | Mouse | copper(II) sulfate | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PAQR5 mRNA | CTD | PMID:19549813 | Paqr5 | Mouse | coumestrol | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of PAQR5 mRNA | CTD | PMID:19167446 | Paqr5 | Mouse | coumestrol | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of PAQR5 mRNA | CTD | PMID:19167446 | Paqr5 | Mouse | Cuprizon | increases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of PAQR5 mRNA | CTD | PMID:26577399 | Paqr5 | Mouse | cyclosporin A | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PAQR5 mRNA | CTD | PMID:20106945 more ... | Paqr5 | Mouse | DDE | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of PAQR5 mRNA | CTD | PMID:38568856 | Paqr5 | Mouse | decabromodiphenyl ether | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in decreased expression of PAQR5 mRNA | CTD | PMID:23914054 | Paqr5 | Mouse | diiodine | multiple interactions | EXP | | 6480464 | [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PAQR5 mRNA | CTD | PMID:36706583 | Paqr5 | Mouse | dorsomorphin | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Paqr5 | Mouse | doxorubicin | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PAQR5 mRNA | CTD | PMID:29803840 | Paqr5 | Mouse | endosulfan | increases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of PAQR5 mRNA | CTD | PMID:29391264 | Paqr5 | Mouse | entinostat | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | entinostat results in increased expression of PAQR5 mRNA | CTD | PMID:26272509 and PMID:27188386 | Paqr5 | Mouse | entinostat | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAQR5 mRNA | CTD | PMID:27188386 | Paqr5 | Mouse | fulvestrant | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PAQR5 gene | CTD | PMID:31601247 | Paqr5 | Mouse | fulvestrant | increases methylation | ISO | PAQR5 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of PAQR5 gene | CTD | PMID:31601247 | Paqr5 | Mouse | lead nitrate | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | lead nitrate results in decreased expression of PAQR5 mRNA | CTD | PMID:21628963 | Paqr5 | Mouse | lipopolysaccharide | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PAQR5 mRNA | CTD | PMID:35811015 | Paqr5 | Mouse | manganese(II) chloride | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | manganese chloride results in decreased expression of PAQR5 mRNA | CTD | PMID:28801915 | Paqr5 | Mouse | methoxychlor | affects methylation | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of PAQR5 gene | CTD | PMID:35440735 | Paqr5 | Mouse | monosodium L-glutamate | increases expression | EXP | | 6480464 | Sodium Glutamate results in increased expression of PAQR5 mRNA | CTD | PMID:22078008 | Paqr5 | Mouse | nickel sulfate | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of PAQR5 mRNA | CTD | PMID:22714537 | Paqr5 | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PAQR5 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of PAQR5 mRNA | CTD | PMID:34911549 | Paqr5 | Mouse | paracetamol | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PAQR5 mRNA | CTD | PMID:29067470 | Paqr5 | Mouse | paraquat | decreases expression | ISO | Paqr5 (Rattus norvegicus) | 6480464 | Paraquat results in decreased expression of PAQR5 mRNA | CTD | PMID:32680482 | Paqr5 | Mouse | phenobarbital | affects expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PAQR5 mRNA | CTD | PMID:19159669 | Paqr5 | Mouse | propanal | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of PAQR5 mRNA | CTD | PMID:26079696 | Paqr5 | Mouse | quercetin | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Quercetin results in increased expression of PAQR5 mRNA | CTD | PMID:21632981 | Paqr5 | Mouse | rac-lactic acid | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PAQR5 mRNA | CTD | PMID:30851411 | Paqr5 | Mouse | resveratrol | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of PAQR5 mRNA | CTD | PMID:19167446 | Paqr5 | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PAQR5 mRNA | CTD | PMID:35811015 | Paqr5 | Mouse | SB 431542 | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Paqr5 | Mouse | sodium arsenite | affects methylation | ISO | PAQR5 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of PAQR5 gene | CTD | PMID:28589171 | Paqr5 | Mouse | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PAQR5 mRNA | CTD | PMID:37682722 | Paqr5 | Mouse | sodium arsenite | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PAQR5 mRNA | CTD | PMID:38568856 | Paqr5 | Mouse | sotorasib | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR5 mRNA | CTD | PMID:36139627 | Paqr5 | Mouse | temozolomide | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PAQR5 mRNA | CTD | PMID:31758290 | Paqr5 | Mouse | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of PAQR5 mRNA | CTD | PMID:23557971 | Paqr5 | Mouse | trametinib | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of PAQR5 mRNA | CTD | PMID:36139627 | Paqr5 | Mouse | trichostatin A | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PAQR5 mRNA | CTD | PMID:24935251 | Paqr5 | Mouse | triclosan | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PAQR5 mRNA | CTD | PMID:30510588 | Paqr5 | Mouse | urethane | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Urethane results in decreased expression of PAQR5 mRNA | CTD | PMID:28818685 | Paqr5 | Mouse | valproic acid | affects expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PAQR5 mRNA | CTD | PMID:25979313 | Paqr5 | Mouse | valproic acid | increases methylation | ISO | PAQR5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PAQR5 gene | CTD | PMID:29154799 | Paqr5 | Mouse | valproic acid | multiple interactions | ISO | PAQR5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAQR5 mRNA | CTD | PMID:27188386 | Paqr5 | Mouse | valproic acid | increases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PAQR5 mRNA | CTD | PMID:19101580 more ... | Paqr5 | Mouse | vinclozolin | decreases methylation | ISO | Paqr5 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of PAQR5 gene | CTD | PMID:31079544 | Paqr5 | Mouse | zoledronic acid | decreases expression | ISO | PAQR5 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of PAQR5 mRNA | CTD | PMID:24714768 | |