Tas2r126 (taste receptor, type 2, member 126) - Rat Genome Database

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Gene: Tas2r126 (taste receptor, type 2, member 126) Mus musculus
Analyze
Symbol: Tas2r126
Name: taste receptor, type 2, member 126
RGD ID: 1552906
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor activity and bitter taste receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be active in membrane. Orthologous to human TAS2R41 (taste 2 receptor member 41).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mGR2; mGR26; mt2r3; mt2r35; T2R1; T2R12; T2R2; T2R26; T2R41; Tas2; Tas2r26; Tas2r41; taste receptor type 2 member 41
RGD Orthologs
Human
Rat
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,411,469 - 42,412,395 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl642,411,469 - 42,412,398 (+)EnsemblGRCm39 Ensembl
GRCm38642,434,535 - 42,435,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,434,535 - 42,435,464 (+)EnsemblGRCm38mm10GRCm38
MGSCv37642,384,534 - 42,385,460 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36642,364,142 - 42,365,068 (+)NCBIMGSCv36mm8
Celera642,379,045 - 42,379,971 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A novel family of mammalian taste receptors. Adler E, etal., Cell 2000 Mar 17;100(6):693-702.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11696554   PMID:11854532   PMID:12139982   PMID:12477932   PMID:12581520   PMID:12679530   PMID:12734386   PMID:21267068   PMID:21873635   PMID:33559206   PMID:36059440   PMID:37045597  


Genomics

Comparative Map Data
Tas2r126
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39642,411,469 - 42,412,395 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl642,411,469 - 42,412,398 (+)EnsemblGRCm39 Ensembl
GRCm38642,434,535 - 42,435,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl642,434,535 - 42,435,464 (+)EnsemblGRCm38mm10GRCm38
MGSCv37642,384,534 - 42,385,460 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36642,364,142 - 42,365,068 (+)NCBIMGSCv36mm8
Celera642,379,045 - 42,379,971 (+)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map620.72NCBI
TAS2R41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387143,477,873 - 143,478,796 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7143,477,873 - 143,478,796 (+)EnsemblGRCh38hg38GRCh38
GRCh377143,174,966 - 143,175,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,885,088 - 142,886,011 (+)NCBINCBI36Build 36hg18NCBI36
Build 347142,691,802 - 142,692,724NCBI
Celera7138,012,198 - 138,013,121 (+)NCBICelera
Cytogenetic Map7q35NCBI
HuRef7137,512,170 - 137,513,093 (+)NCBIHuRef
CHM1_17143,111,911 - 143,112,834 (+)NCBICHM1_1
T2T-CHM13v2.07144,833,246 - 144,834,169 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27142,577,066 - 142,577,989 (+)NCBI
Tas2r126
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8472,300,448 - 72,301,374 (+)NCBIGRCr8
mRatBN7.2471,333,821 - 71,334,747 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl471,333,821 - 71,334,747 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx476,260,333 - 76,261,259 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0472,173,580 - 72,174,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0470,593,136 - 70,594,062 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0471,836,677 - 71,837,603 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl471,836,677 - 71,837,603 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04136,637,499 - 136,638,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4470,215,672 - 70,216,598 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1470,491,801 - 70,492,728 (+)NCBI
Celera466,263,693 - 66,264,619 (+)NCBICelera
Cytogenetic Map4q24NCBI
TAS2R41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,230,851 - 6,231,777 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,230,851 - 6,231,777 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,219,842 - 7,220,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,084,491 - 6,085,417 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,084,491 - 6,085,417 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,032,471 - 6,033,397 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,884,022 - 5,884,948 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0165,959,197 - 5,960,123 (-)NCBIUU_Cfam_GSD_1.0
TAS2R41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,780,808 - 6,781,731 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,780,212 - 6,781,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,018,210 - 7,019,869 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAS2R41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121112,373,893 - 112,376,564 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21112,374,760 - 112,375,680 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660729,122,230 - 9,123,459 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:93
Interacting mature miRNAs:95
Transcripts:ENSMUST00000059534
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1771159851711719Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348703611Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797146118069Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61771159851711719Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122146751333Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61771159851711719Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348703611Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345291115Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707443297168Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348703611Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122146751333Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse

Markers in Region
UniSTS:488668  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38642,434,535 - 42,435,461UniSTSGRCm38
MGSCv37642,384,534 - 42,385,460UniSTSGRCm37
Celera642,379,045 - 42,379,971UniSTS
Cytogenetic Map6B2.1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000059534   ⟹   ENSMUSP00000056581
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl642,411,469 - 42,412,398 (+)Ensembl
GRCm38.p6 Ensembl642,434,535 - 42,435,464 (+)Ensembl
RefSeq Acc Id: NM_207028   ⟹   NP_996911
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39642,411,469 - 42,412,395 (+)NCBI
GRCm38642,434,535 - 42,435,461 (+)ENTREZGENE
MGSCv37642,384,534 - 42,385,460 (+)RGD
Celera642,379,045 - 42,379,971 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_996911 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI26975 (Get FASTA)   NCBI Sequence Viewer  
  DAA01237 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000056581
  ENSMUSP00000056581.5
GenBank Protein P59532 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_996911   ⟸   NM_207028
- UniProtKB: A0JNU7 (UniProtKB/Swiss-Prot),   Q7M704 (UniProtKB/Swiss-Prot),   P59532 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000056581   ⟸   ENSMUST00000059534

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P59532-F1-model_v2 AlphaFold P59532 1-308 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2681273 AgrOrtholog
Ensembl Genes ENSMUSG00000048284 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000059534 ENTREZGENE
  ENSMUST00000059534.5 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro T2R UniProtKB/Swiss-Prot
KEGG Report mmu:387353 UniProtKB/Swiss-Prot
MGD MGI:2681273 ENTREZGENE
NCBI Gene 387353 ENTREZGENE
PANTHER TASTE RECEPTOR TYPE 2 UniProtKB/Swiss-Prot
  TASTE RECEPTOR TYPE 2 MEMBER 41 UniProtKB/Swiss-Prot
Pfam TAS2R UniProtKB/Swiss-Prot
PhenoGen Tas2r126 PhenoGen
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0JNU7 ENTREZGENE
  P59532 ENTREZGENE
  Q7M704 ENTREZGENE
  T2R41_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A0JNU7 UniProtKB/Swiss-Prot
  Q7M704 UniProtKB/Swiss-Prot