Ighm<sup>em1Ang</sup> (immunoglobulin heavy constant mu; ZFN induced mutant1, Ang) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ighmem1Ang (immunoglobulin heavy constant mu; ZFN induced mutant1, Ang) Rattus norvegicus
Analyze
Symbol: Ighmem1Ang
Name: immunoglobulin heavy constant mu; ZFN induced mutant1, Ang
RGD ID: 150523756
Description: The ZFN induced mutation in this rat allele comprised a 64 bp deletion of the IgM CH1 domain and resulted of a stop codon.
ASSOCIATED WITH decreased B cell number; decreased IgA level; decreased IgE level; ASSOCIATED WITH B cell deficiency
Type: allele  of Ighm  
Previously known as: Ighm^[em1Ang]
Is Marker For: Strains:   SD-Ighmem1Ang  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Characterization of immunoglobulin heavy chain knockout rats. Ménoret S, etal., Eur J Immunol. 2010 Oct;40(10):2932-41. doi: 10.1002/eji.201040939.

Genomics


Related Rat Strains
The following Strains have been annotated to Ighmem1Ang
SD-Ighmem1Ang    


Expression


Sequence

Nucleotide Sequences


Additional Information