MIRLET7F (microRNA let-7f) - Rat Genome Database

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Gene: MIRLET7F (microRNA let-7f) Pan paniscus
Analyze
Symbol: MIRLET7F
Name: microRNA let-7f
RGD ID: 14398613
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: ppa-let-7f
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21145,260,374 - 45,260,451 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1945,262,754 - 45,262,831 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0965,290,856 - 65,290,933 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IEA)

References
Additional References at PubMed
PMID:16381832   PMID:28640911  


Genomics


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NR_163103
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21145,260,374 - 45,260,451 (-)NCBI
NHGRI_mPanPan1945,262,754 - 45,262,831 (-)NCBI
Mhudiblu_PPA_v0965,290,856 - 65,290,933 (+)NCBI

Additional Information

Database Acc Id Source(s)
miRBase MI0039810 ENTREZGENE
NCBI Gene MIRLET7F ENTREZGENE
RNAcentral URS00003B7674 RNACentral
  URS00007E4FE0 RNACentral