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Gene: DEFB134 (defensin beta 134) Sus scrofa

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Symbol:

DEFB134

Name:

defensin beta 134

RGD ID:

14264834

Description:

INVOLVED IN defense response (inferred); defense response to bacterium (inferred); innate immune response (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); thoracic aortic aneurysm (ortholog); FOUND IN extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

beta-defensin 134

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	15,170,853 - 15,176,926 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	15,171,675 - 15,176,787 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	16,362,997 - 16,365,210 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DEFB134	Pig	Neurodevelopmental Disorders		ISO	DEFB134 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868
DEFB134	Pig	thoracic aortic aneurysm		ISO	DEFB134 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Thoracic aortic aneurysm	ClinVar	PMID:32748548

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DEFB134	Pig	defense response	involved_in	IEA	UniProtKB-KW:KW-0211	150520179		UniProt	GO_REF:0000043
DEFB134	Pig	defense response to bacterium	involved_in	IEA	UniRule:UR000048414	150520179		UniProt	GO_REF:0000104
DEFB134	Pig	defense response to bacterium	involved_in	IEA	UniProtKB-KW:KW-0044	150520179		UniProt	GO_REF:0000043
DEFB134	Pig	innate immune response	involved_in	IEA	InterPro:IPR025933	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DEFB134	Pig	extracellular region	located_in	IEA	UniRule:UR000048414	150520179		UniProt	GO_REF:0000104
DEFB134	Pig	extracellular region	located_in	IEA	InterPro:IPR025933	150520179		InterPro	GO_REF:0000002
DEFB134	Pig	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
DEFB134	Pig	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044

DEFB134
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	15,170,853 - 15,176,926 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	15,171,675 - 15,176,787 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	16,362,997 - 16,365,210 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DEFB134
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	11,993,174 - 12,000,752 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	11,993,174 - 12,000,752 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	11,850,683 - 11,858,261 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	11,888,898 - 11,891,169 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	10,980,841 - 10,983,113 (-)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	10,782,221 - 10,784,493 (-)	NCBI		HuRef
CHM1_1	8	12,292,895 - 12,295,167 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	7,739,516 - 7,747,095 (+)	NCBI		T2T-CHM13v2.0

Defb134
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955403	53,215,271 - 53,221,539 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC117981327
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	30,827,472 - 30,837,029 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	4,491,356 - 4,494,976 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	7,201,574 - 7,205,211 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DEFB134
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	25,912,325 - 25,915,441 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	25,912,277 - 25,915,451 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	26,569,408 - 26,572,524 (+)	NCBI		Dog10K_Boxer_Tasha
UMICH_Zoey_3.1	25	26,012,066 - 26,015,179 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	25,916,716 - 25,919,831 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	26,067,898 - 26,071,014 (+)	NCBI		UU_Cfam_GSD_1.0

DEFB134
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	8	7,142,308 - 7,144,583 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	35,292,728 - 35,295,234 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in DEFB134
219 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	mesenchyme	mesoderm	nervous system	renal system	reproductive system
1	1	1	1	1	1


RefSeq Transcripts	NM_001435252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013990300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002338938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU582875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000048565 ⟹ ENSSSCP00000032647

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	15,170,853 - 15,176,926 (-)	Ensembl

RefSeq Acc Id:

XM_013990300 ⟹ XP_013845754

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	15,171,675 - 15,176,787 (-)	NCBI

Sequence:

show sequence

TCTGGTGTTGTGGCTGTGGTGTACGCCAGCTGCTCCAGCTTTTATTCAACCCCTAGGCTAGGAACTTCCATATGCCACACATGCAGCCCTAAAAAGAAAACAAAGAAAAAGAAAAAGCATACAGTTCC
CAGGTCTCTGTTAGAACTCTTGGGAAACCCAGGTCGGGGAGCAGTGCCTTTGACAATAGGAAAAGCTGTCAAACAGGAAAGGGCTGCCTGGTTTTTCCTCAGATAAGCATGGCCAACGCAGCTGCCTC
AGGCAAGGTCAGTGCAGCACATCCACCTGGAGCAAATCACACCACAGACCTGACAGGGCTGTACAGGATGTGTGCTCACCTTTTCTCTCTGCTCTCTGACCGCTTGCGTCAGCCTTGCCACCAGCCTC
CTCAACAGACACTACCAGCCATGAAGCCTCTCCTCCTTGTGTTTGTGTCTCTCTTCTTTTGGGATCCAGTGCTGGCAGGCTTGAATCCATTATCATCAGAACTTCACAAGACATGTTATAAAAATGGT
ACCTGCCGATTTGAGTGCTATGGAAGTGAAATGTTAGTTGCCTACTGCCTGTTTCAGCTGGAGTGCTGTATCAAAGGAAACCCTGACCCCTGACATGAGAAACCAATTAATGCCAATTAATCTGAAAG
TCCTTGACACGCCCTCTCACAGCCAGGGAACTTAAACTAAACCTTGACGCTGTGATGTGCCCACAGCCACTGGTCTTTAGCATCTTTATATAATCCATCAGAACATCAGAATCTTATGATCTCAGATT
TGCAAAGCTAGGCTGCAGGCTTCCTAAAGACCAGCAAGGTTCTCATGAAAACTATTTAGAATACGTTTTCTCACTTCAAATGGATATTCATGCTCCTTCAGTGTGTATTTTTCTCTTCACTCATAAAA
AGGTTGTATTATTTAAAAAGGCTTCAAATTACAGAAATATCTTTTTACACCTAAGCTTTACCCTACCATCCCTTCAGTTCCCCATCCACCTTTTCTTTGAACCTCCCATCTGTACAGGAACAGATCTG
CCCAAGCCCCCTGATGACCTCATATAGCTCTCACATGGACCACATGGGCAAGACTTAACTGCAGGGAGGCACAAGTTTTGACTGAGTATGACCCTGCAGTTCTTCTTGAAACACAAGGATAAAAGCCA
TGTTGTGATGGGCTGGCATAAGGCAGGTTCTTACCCACCATCCTTGTTTCAGAGAGTGAAATCAAAGGACTTTCCACCTCAGCCCCTTCAGGGTTCAGCCATCAGACCAGATGGCTATGGCTTAGAGT
TGTCCTCTCAGCAGCTGAATGACTCACCACCCCTGCTACCCATCATCTGGCCCCTCTCGTTGAGTCCCATCCTGTGGGACTAGGAGCTAACACACCTGCTGGTCTTGCTTTGCTGCGTATACAAGTAA
TAAACTATCTAAATCCATTTGGATTCATTGTGTTCTTTGTCAGCCAACCTTGCAAAAGTGGACAGGCAAAGCAGGCAACTTCTGCTGGGGTTCTGGCTATCCTACTGACTATTGCAATGCTGTTGAAT
ATCTGCCTAATGGCTCTGGCTCTACACCATCGGCCTACATACAGATGCATAGGTGAGTTCTACATGTGCTACTCAGGATGAGGGTGGTGAAGGGTGGTGGATTCTGGTTGCCTGAAGAGCAATTTTCT
TCAGCCTCAGTGCTAAATACAGCTTGGACCCTGTCATGATGTCGAGAGGGTGGGGCTCTAGCTGCAAACAGCCAATAGCTGATCTGGCACAAGGCTGAGGAAACAATGGCTAAGTCTTTGCCTGAAAT
GACAGTACTGCTCTTCCAGCCACTCACTGAAACTGGGGGAAGATGAAAAACAGAACAGTTGTTGAGAAGGAATAAGGGGCCGCAAGGGGTTCCACCTTCCCCGACACTGTTCAACCTTTGATAAAATC
CAGTGTGGGTGTCTTTAGGGAAGAAGATACTAAAAAAAAAAGAACAAGGAGGAGAAGGAGGGAGAGGGGTAGGGGGAGGAGGAGGAGAAGAAGGAGAGGAAGAGGAAGAAGCTAGAAACCGTTCTCAC
AGTGGCCCAAACTCTGCTGTGGAGTCAGTAGGAGAGATGGTATCAAATGGACTGGAATTGGAGATGGCCTGGAATGGTGACCATGGTTAAGTATCCAAAGTAAAAAAGGCATCCAGACAGGACCCAGT
AAAACTATAAGACTCTGAAGGAGAAGGGGAATCCTTACATGAAGAGCAGTGGATCTTTTGCAATTGTGCCTCCCGATATCCCAGGTATCCTTGGCCTTGCTTCTCATTTTCTGGCATGTACATCCTTT
AAACACAGACAGAAACTGAAACTTGAAGATAACCCAGCCCTCTGACTATCCAAAGAGCCTCTCTTTTTTAACTGGATGAGGGAACATAGAGACTCCTTAGAGAGGTGTTCCCCAAGCAGAGAGAGAGA
GAGAGAGAGAGAGAGAGAAAAACCTATGCGCCCCCTGCTGAAAGAATCAGAAACTCTCTGGAATCTGGTGCACGTCAAGAAACTTCCCTCCACGTAAGACAGATAAGCCAACACCACACTGCCTATCC
CTTACTATTTCACAAACCCAAACCTCTATATTCATATAACCCATCAGGAAATGACTCTGTTATTAACAATGGTCACTTCAAACTGCCTTATTCCCTTGACATAAAGTGTACATATCACATGAGATCCC
TCTTGATGTGCTGCATATATACAAGGAGATATTACTCAGCCATAAAAAAGAATGAAATCTTGTCATTTGAGACAACATGGGTGGACCTAGAAGGTATTATGCTAAGTGAAATTATCTAAGAAAGACAA
ATACCATATGATCTCACCTCTATTGGAAATCTAAGAAACAAAGCAAATGAACAAACCTAACAAAACAGAAACAGAATCATAGATTCAGAGAACAAACAGGTGGTTGCCAGGGGGAAGAAGGTAGGGTG
TGGGGGGAGAGTAATAAATGAGGGAGATTAATAGTAACCAACTTCTTGTTATTGAAAATAATTTTTTTTTTGTCTTTTGTCTTTTGTCCTTTTAGGGCCATACCCATGGCATATGGAGGTTCCTGGGC
TAGGGGTCTAATCAGAGCTGTTGCCGCC

hide sequence

RefSeq Acc Id:

XR_002338938

Type:

NON-CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	15,174,193 - 15,176,452 (-)	NCBI

Sequence:

show sequence

CTTTTCTCTCTGCTCTCTGACCGCTTGCGTCAGCCTTGCCACCAGCCTCCTCAACAGACACTAC
CAGCCATGAAGCCTCTCCTCCTTGTGTTTGTGTCTCTCTTCTTTTGGGATCCAGTGCTGGCAGGTACACAGAGAAAGATTTGGAACTGCCTGTTCCAGGAGAATTAATACAAGAAATGTCTGATTAGA
TGAGACAGCAGTTAGAGAGACGTGAAGGAAAACGCTGGCATCACACTCTAGCTTGACCATATCTGTTACTGACCTTGGAAATCTCATCATGAATATTCACTATCTCAGAATGAGTTCATATCCAGTAG
GGTCCTACTTAATTTCTCATCCTCTCTTAAGCCTTCTCTAGGCAGATGAACCAGATTTTCAGATCATGTGACTCAAGAGGCTGGATTTAAGAATCATAGGATCCAGGGCTCTGGAAGCTATTGATGGG
ACTATGCCACTAAGGTTCATGGCAGTGCATTCAGACCTCTAGACAGTCAACAGCCACATAGAGTCTACAATATTCCCTTTAGTGGCTTAGACATTCCCAGAGCTTGTCACTTCCATAGGAATTTTTTC
TTTCTTTATATAGACCATTACGTGTTTCATATCTAGATCATTACTCTCTATCTTCTTAGGCTTCCATCTTGCTGGCTAAGTAACCCTTACCCCTTCTTTTTTCCTAGAGGACAATTATCCTCCAGGAC
ATGACGGATAGGGTGTAAAATTTCTACAGATGGTCAAATTTTAGAACTCTTTTCCTTTTAACACCCTCTCACATGAAAATAAACCTTCATATTCAGATGAGTCTATGGAGTTACATGTCCACAAAACT
ATAAGCCCATCTCAAGTACCCTGGGCTCCAAGAAACCATATCATCTTCAGAACTGATTTCATCCTCCTCTGAACTCACAACACCACTCCATGTTGCACACACCTCACTGGACTCATCATGTTTTCTTC
TCTCTCACAGGCTTGAATCCATTATCATCAGAACTTCACAAGACATGTTATAAAAATGGTACCTGCCGATTTGAGTGCTATGGAAGTGAAATGTTAGTTGCCTACTGCCTGTTTCAGCTGGAGTGCTG
TA

hide sequence


Protein RefSeqs	NP_001422181	(Get FASTA)	NCBI Sequence Viewer
	XP_013845754	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000078099
	ENSSSCP00000078099.1
	ENSSSCP00025014695.1
	ENSSSCP00030001655.1
	ENSSSCP00035039726.1
	ENSSSCP00040047177.1
	ENSSSCP00045021569.1
	ENSSSCP00055000038.1
	ENSSSCP00065014142.1

RefSeq Acc Id:	XP_013845754 ⟸ XM_013990300
- Sequence:	show sequence MANAAASGKVSAAHPPGANHTTDLTGLYRMCAHLFSLLSDRLRQPCHQPPQQTLPAMKPLLLVFVSLFFWDPVLAGLNPLSSELHKTCYKNGTCRFECYGSEMLVAYCLFQLECCIKGNPDP hide sequence

Ensembl Acc Id:

ENSSSCP00000032647 ⟸ ENSSSCT00000048565

Protein Domains

Beta-defensin

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000032245	Ensembl
	ENSSSCG00000062644	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025026068	UniProtKB/TrEMBL
	ENSSSCG00030003245	UniProtKB/TrEMBL
	ENSSSCG00035070027	UniProtKB/TrEMBL
	ENSSSCG00040074975	UniProtKB/TrEMBL
	ENSSSCG00045018276	UniProtKB/TrEMBL
	ENSSSCG00055000023	UniProtKB/TrEMBL
	ENSSSCG00065025526	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000095590	ENTREZGENE
	ENSSSCT00000095590.1	UniProtKB/TrEMBL
	ENSSSCT00025035233.1	UniProtKB/TrEMBL
	ENSSSCT00030004188.1	UniProtKB/TrEMBL
	ENSSSCT00035094582.1	UniProtKB/TrEMBL
	ENSSSCT00040103836.1	UniProtKB/TrEMBL
	ENSSSCT00045031115.1	UniProtKB/TrEMBL
	ENSSSCT00055000045.1	UniProtKB/TrEMBL
	ENSSSCT00065034154.1	UniProtKB/TrEMBL
InterPro	Beta_defensin	UniProtKB/TrEMBL
KEGG Report	ssc:106508066	UniProtKB/TrEMBL
NCBI Gene	DEFB134	ENTREZGENE
Pfam	Defensin_beta_2	UniProtKB/TrEMBL
UniProt	A0A8D0JFH0_PIG	UniProtKB/TrEMBL
	A0A8D0V7B1	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8W4FF93	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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