CD58 (CD58 molecule) - Rat Genome Database

Name: CD58
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: CD58 (CD58 molecule) Sus scrofa

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Symbol:

CD58

Name:

CD58 molecule

RGD ID:

14239462

Description:

INVOLVED IN cellular response to tumor necrosis factor (ortholog); cellular response to type II interferon (ortholog); positive regulation of interleukin-8 production (ortholog); ASSOCIATED WITH multiple sclerosis (ortholog); peripheral T-cell lymphoma (ortholog); FOUND IN cell surface (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CD58 antigen; lymphocyte function-associated antigen 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	104,169,883 - 104,227,917 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	104,170,827 - 104,225,029 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	114,340,887 - 114,369,778 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

multiple sclerosis (ISO)

peripheral T-cell lymphoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to tumor necrosis factor (ISO)

cellular response to type II interferon (ISO)

heterotypic cell-cell adhesion (IBA)

immune response (IBA)

positive regulation of interleukin-8 production (ISO)

Cellular Component

cell surface (IBA,ISO)

membrane (IEA)

Molecular Function

protein binding (ISO)

signaling receptor binding (IBA)

References

Additional References at PubMed

PMID:13679072	PMID:15114100	PMID:30032202

Genomics

Comparative Map Data

CD58
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	104,169,883 - 104,227,917 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	104,170,827 - 104,225,029 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	114,340,887 - 114,369,778 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD58
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	116,514,534 - 116,571,026 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	116,514,534 - 116,571,039 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	117,057,156 - 117,113,648 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	116,858,680 - 116,915,126 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	116,769,198 - 116,825,645	NCBI
Celera	1	115,285,654 - 115,342,230 (-)	NCBI		Celera
Cytogenetic Map	1	p13.1	NCBI
HuRef	1	114,916,575 - 114,973,314 (-)	NCBI		HuRef
CHM1_1	1	117,171,988 - 117,228,583 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	116,524,958 - 116,581,474 (-)	NCBI		T2T-CHM13v2.0

CD58
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	109,167,445 - 109,223,671 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	108,766,913 - 108,823,153 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	85,992,828 - 86,049,066 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	121,045,460 - 121,101,636 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	121,045,460 - 121,101,636 (+)	Ensembl	panpan1.1		panPan2

CD58
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	53,969,207 - 53,997,306 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	53,973,029 - 53,995,672 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	53,616,375 - 53,657,734 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	54,850,583 - 54,891,921 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	17	53,887,761 - 53,929,050 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	53,923,713 - 53,965,058 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	54,497,294 - 54,538,606 (-)	NCBI		UU_Cfam_GSD_1.0

CD58
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	17,152,663 - 17,208,646 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	17,152,777 - 17,208,671 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	19,843,773 - 19,899,845 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in CD58
1740 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_213795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF469666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY303628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU468823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU481485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU856185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01026392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000007383 ⟹ ENSSSCP00000007188

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	4	104,169,883 - 104,227,917 (+)	Ensembl

RefSeq Acc Id:

NM_213795 ⟹ NP_998960

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	4	104,170,827 - 104,225,029 (+)	NCBI

Sequence:

show sequence

AAAGGCCGGACCGCCATGGCCTCGGGGAGAGCCCTAAGGTGGGCCGTGCGGGCCCCCGACGTGA
TCTTCCTGCTGCTCTGGTTGGATTTCATCCACTGTGATTCCAAAGTAATATATGGAGCCCTGCA
CAAGAATGTAACTTTACGTGCCTCAAGCTCTCAAACCTTTCAGGAAATCATATGGAAGAAGGGA
AAAGATAAAGCTGTTGAATGGGAAGAGCAATACAATGTCACAGCTTTCCCGCCTTTTGTAGATA
GGGTTCACTTAAACACTGGGTCGGGCGACCTCACCATCTACAACCTGGCCTTCGAAGATGAAGG
TGACTATCAAATTGAATCTCCCAGTGTCAAAAACAGCAGCAAGTTCATCCTCAGGGTGGTTGAG
CCTCTTCCAGAGCCAGAACTATATTGCGAGTCGACTGAGGGGAATATTAGCGTCCGATGCCTGA
TCCTTGCAGCTTCCTTGAGGCACATAGACCTCATACAGTACTCTTGGAATTGCCCTCCAACAGT
ATCGTGTCAAGCTGGCTTAGGACCATCTGAAATGTATATTACCAAGGAATCTGATTTTTCACAA
GACGTCCAGTGCATCATTAGCAATCCATTATTCAAAAGTTCAGCATCAGCCTCTTTGTCATCCT
GCGCCCCCACTGATAATACAAGGCATAGATATGTGCTTGTCGCAGTACTGCCAGCGGTGATAGT
TGCCTTGGTACTTTTAAAATGGTTTCTGGCGCGTCGTAGCGGATAAACCCACAGAACCAGCATC
CACTGGTTGGTAACAGAAGGGGAAACCAAGCCCTTGGTAATAACTAAGTTATTTCAGCAACTCC
GAGAAGACATCTGATTTACCATCCGAGTGTTACCTTATTACCGATGCCTCCAGTCGTTCACTGG
TAGGCCACGAGGGAGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_998960	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL76278	(Get FASTA)	NCBI Sequence Viewer
	AAP59042	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000007188
	ENSSSCP00000007188.4
	ENSSSCP00025013350.1
	ENSSSCP00035021960.1
	ENSSSCP00045007595.1
	ENSSSCP00055012359.1
	ENSSSCP00065034020.1
	ENSSSCP00070006438.1
	ENSSSCP00070006443.1

RefSeq Acc Id:	NP_998960 ⟸ NM_213795
- Peptide Label:	precursor
- UniProtKB:	Q8SQB6 (UniProtKB/TrEMBL), A0A4X1SUB5 (UniProtKB/TrEMBL), A0A8D1CUH5 (UniProtKB/TrEMBL), A0A8D1PZJ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASGRALRWAVRAPDVIFLLLWLDFIHCDSKVIYGALHKNVTLRASSSQTFQEIIWKKGKDKAV EWEEQYNVTAFPPFVDRVHLNTGSGDLTIYNLAFEDEGDYQIESPSVKNSSKFILRVVEPLPEP ELYCESTEGNISVRCLILAASLRHIDLIQYSWNCPPTVSCQAGLGPSEMYITKESDFSQDVQCI ISNPLFKSSASASLSSCAPTDNTRHRYVLVAVLPAVIVALVLLKWFLARRSG hide sequence

Ensembl Acc Id:

ENSSSCP00000007188 ⟸ ENSSSCT00000007383

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000006738	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025023484	UniProtKB/TrEMBL
	ENSSSCG00035041068	UniProtKB/TrEMBL
	ENSSSCG00045006702	UniProtKB/TrEMBL
	ENSSSCG00055008052	UniProtKB/TrEMBL
	ENSSSCG00065057137	UniProtKB/TrEMBL
	ENSSSCG00070004156	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000007383	ENTREZGENE
	ENSSSCT00000007383.5	UniProtKB/TrEMBL
	ENSSSCT00025031886.1	UniProtKB/TrEMBL
	ENSSSCT00035054583.1	UniProtKB/TrEMBL
	ENSSSCT00045011161.1	UniProtKB/TrEMBL
	ENSSSCT00055015721.1	UniProtKB/TrEMBL
	ENSSSCT00065078220.1	UniProtKB/TrEMBL
	ENSSSCT00070007829.1	UniProtKB/TrEMBL
	ENSSSCT00070007834.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
KEGG Report	ssc:396702	UniProtKB/TrEMBL
NCBI Gene	CD58	ENTREZGENE
PANTHER	LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3	UniProtKB/TrEMBL
	SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A4X1SUB5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1CUH5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1PZJ7	ENTREZGENE, UniProtKB/TrEMBL
	F1SAX5_PIG	UniProtKB/TrEMBL
	Q7YS40_PIG	UniProtKB/TrEMBL
	Q8SQB6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:86422	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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