PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) - Rat Genome Database

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Gene: PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) Sus scrofa
Analyze
Symbol: PKMYT1
Name: protein kinase, membrane associated tyrosine/threonine 1
RGD ID: 14236895
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); protein kinase activity (inferred); INVOLVED IN negative regulation of G2/M transition of mitotic cell cycle (inferred); ASSOCIATED WITH COVID-19 (ortholog); developmental and epileptic encephalopathy 1 (ortholog); epilepsy (ortholog); FOUND IN cytoplasm (inferred); Golgi apparatus (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; protein kinase Myt1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,201,878 - 39,210,125 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,201,819 - 39,209,261 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,490,568 - 40,496,602 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PKMYT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,201,878 - 39,210,125 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,201,819 - 39,209,261 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,490,568 - 40,496,602 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKMYT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,972,808 - 2,980,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,968,024 - 2,980,479 (-)EnsemblGRCh38hg38GRCh38
GRCh37163,022,809 - 3,030,447 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,962,793 - 2,970,475 (-)NCBINCBI36Build 36hg18NCBI36
Celera163,228,238 - 3,235,920 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,995,283 - 3,002,445 (-)NCBIHuRef
CHM1_1163,022,772 - 3,030,521 (-)NCBICHM1_1
T2T-CHM13v2.0162,999,487 - 3,007,174 (-)NCBIT2T-CHM13v2.0
Pkmyt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,945,385 - 23,955,709 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,945,310 - 23,955,709 (+)EnsemblGRCm39 Ensembl
GRCm381723,726,336 - 23,736,735 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,726,336 - 23,736,735 (+)EnsemblGRCm38mm10GRCm38
MGSCv371723,863,303 - 23,873,696 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,454,063 - 23,464,364 (+)NCBIMGSCv36mm8
Celera1724,220,014 - 24,230,508 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.02NCBI
Pkmyt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,252,805 - 13,263,584 (+)NCBIGRCr8
mRatBN7.21012,748,221 - 12,758,995 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,748,237 - 12,758,995 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,492,526 - 17,503,316 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,981,319 - 16,992,106 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,480,898 - 12,491,719 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,061,077 - 13,072,277 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,061,170 - 13,073,283 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,880,557 - 12,891,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,982,319 - 12,993,706 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,982,318 - 12,993,697 (+)NCBI
Celera1012,443,567 - 12,454,296 (+)NCBICelera
Cytogenetic Map10q12NCBI
Pkmyt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,364,031 - 14,372,365 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,368,110 - 14,372,365 (+)NCBIChiLan1.0ChiLan1.0
PKMYT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,517,578 - 3,549,487 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,295,971 - 7,327,895 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,914,651 - 1,946,407 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,086,713 - 3,094,475 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,082,265 - 3,094,477 (-)Ensemblpanpan1.1panPan2
PKMYT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,200,445 - 38,210,458 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,200,322 - 38,210,414 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,440,999 - 39,450,948 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,511,079 - 38,521,031 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,510,937 - 38,520,987 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,196,845 - 38,206,793 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,169,331 - 38,179,322 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,645,560 - 38,655,092 (+)NCBIUU_Cfam_GSD_1.0
Pkmyt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,512,794 - 105,521,087 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,188,442 - 1,199,079 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,191,534 - 1,196,532 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKMYT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,712,423 - 2,722,122 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,712,448 - 2,716,661 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,112,937 - 28,122,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkmyt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824715,770 - 724,530 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824715,818 - 724,535 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PKMYT1
92 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
9 1 22 3 1 4 9 7 22 4 2

Sequence


Ensembl Acc Id: ENSSSCT00000030606   ⟹   ENSSSCP00000023034
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl339,201,878 - 39,210,125 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000037106   ⟹   ENSSSCP00000052537
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl339,201,878 - 39,209,263 (+)Ensembl
RefSeq Acc Id: NM_001159310   ⟹   NP_001152782
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,202,653 - 39,209,150 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085610   ⟹   XP_020941269
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,883 - 39,209,058 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085611   ⟹   XP_020941270
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,202,567 - 39,209,058 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085612   ⟹   XP_020941271
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,940 - 39,209,058 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085613   ⟹   XP_020941272
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,837 - 39,209,261 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085614   ⟹   XP_020941273
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,877 - 39,209,255 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085615   ⟹   XP_020941274
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,878 - 39,209,257 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021085616   ⟹   XP_020941275
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1339,201,819 - 39,209,257 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020941275   ⟸   XM_021085616
- Peptide Label: isoform X5
- UniProtKB: A0A4X1VVH5 (UniProtKB/TrEMBL),   I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941272   ⟸   XM_021085613
- Peptide Label: isoform X3
- UniProtKB: I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941273   ⟸   XM_021085614
- Peptide Label: isoform X4
- UniProtKB: I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941274   ⟸   XM_021085615
- Peptide Label: isoform X5
- UniProtKB: A0A4X1VVH5 (UniProtKB/TrEMBL),   I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941269   ⟸   XM_021085610
- Peptide Label: isoform X1
- UniProtKB: I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941271   ⟸   XM_021085612
- Peptide Label: isoform X2
- UniProtKB: I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941270   ⟸   XM_021085611
- Peptide Label: isoform X2
- UniProtKB: I3LG41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152782   ⟸   NM_001159310
- UniProtKB: C0SW07 (UniProtKB/TrEMBL),   I3LG41 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000023034   ⟸   ENSSSCT00000030606
Ensembl Acc Id: ENSSSCP00000052537   ⟸   ENSSSCT00000037106
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029264 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015074172 UniProtKB/TrEMBL
  ENSSSCG00025013071 UniProtKB/TrEMBL
  ENSSSCG00030020513 UniProtKB/TrEMBL
  ENSSSCG00035051470 UniProtKB/TrEMBL
  ENSSSCG00040027970 UniProtKB/TrEMBL
  ENSSSCG00045007129 UniProtKB/TrEMBL
  ENSSSCG00050020563 UniProtKB/TrEMBL
  ENSSSCG00055019871 UniProtKB/TrEMBL
  ENSSSCG00060074685 UniProtKB/TrEMBL
  ENSSSCG00065030070 UniProtKB/TrEMBL
  ENSSSCG00070026636 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000030606 ENTREZGENE
  ENSSSCT00000030606.4 UniProtKB/TrEMBL
  ENSSSCT00015100000.1 UniProtKB/TrEMBL
  ENSSSCT00025017322.1 UniProtKB/TrEMBL
  ENSSSCT00030028373.1 UniProtKB/TrEMBL
  ENSSSCT00035068544.1 UniProtKB/TrEMBL
  ENSSSCT00040037499.1 UniProtKB/TrEMBL
  ENSSSCT00045011852.1 UniProtKB/TrEMBL
  ENSSSCT00050027751.1 UniProtKB/TrEMBL
  ENSSSCT00055038995.1 UniProtKB/TrEMBL
  ENSSSCT00060102331.1 UniProtKB/TrEMBL
  ENSSSCT00065040570.1 UniProtKB/TrEMBL
  ENSSSCT00070053404.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CC_SR_Kinase UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report ssc:100286809 UniProtKB/TrEMBL
NCBI Gene PKMYT1 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED UniProtKB/TrEMBL
  MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A4X1VVH5 ENTREZGENE, UniProtKB/TrEMBL
  C0SW07 ENTREZGENE, UniProtKB/TrEMBL
  I3LG41 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91480 ENTREZGENE