MICU1 (mitochondrial calcium uptake 1) - Rat Genome Database

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Gene: MICU1 (mitochondrial calcium uptake 1) Sus scrofa
Analyze
Symbol: MICU1
Name: mitochondrial calcium uptake 1
RGD ID: 14194817
Description: ENCODES a protein that exhibits calcium channel regulator activity (ortholog); INVOLVED IN calcium import into the mitochondrion (inferred); calcium ion import (inferred); calcium ion transport (inferred); ASSOCIATED WITH basal ganglia disease (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcium uptake protein 1, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1475,203,752 - 75,445,626 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21481,253,348 - 81,512,159 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MICU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1475,203,752 - 75,445,626 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21481,253,348 - 81,512,159 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MICU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381072,367,340 - 72,626,079 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1072,367,340 - 72,626,131 (-)EnsemblGRCh38hg38GRCh38
GRCh371074,127,098 - 74,385,837 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361073,797,104 - 74,055,905 (-)NCBINCBI36Build 36hg18NCBI36
Build 341073,797,103 - 74,055,843NCBI
Celera1067,411,407 - 67,671,032 (-)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1068,121,247 - 68,379,597 (-)NCBIHuRef
CHM1_11074,408,857 - 74,667,691 (-)NCBICHM1_1
T2T-CHM13v2.01073,238,332 - 73,497,425 (-)NCBIT2T-CHM13v2.0
Micu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391059,538,385 - 59,699,956 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1059,538,299 - 59,699,954 (+)EnsemblGRCm39 Ensembl
GRCm381059,702,563 - 59,864,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1059,702,477 - 59,864,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv371059,165,383 - 59,326,871 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361059,097,992 - 59,259,480 (+)NCBIMGSCv36mm8
Celera1060,801,731 - 60,961,581 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.6NCBI
Micu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82028,211,774 - 28,357,928 (+)NCBIGRCr8
mRatBN7.22027,668,681 - 27,816,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2027,668,747 - 27,814,964 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2028,680,580 - 28,826,479 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02028,066,842 - 28,212,756 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02028,810,036 - 28,955,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02029,284,833 - 29,433,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,284,853 - 29,432,258 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,089,733 - 31,237,179 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,143,391 - 27,174,811 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2029,110,269 - 29,256,591 (+)NCBICelera
Cytogenetic Map20q11NCBI
Micu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543719,020,652 - 19,253,789 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543719,021,012 - 19,250,831 (+)NCBIChiLan1.0ChiLan1.0
MICU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2884,515,095 - 84,779,743 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11084,520,416 - 84,785,055 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01068,887,361 - 69,152,242 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11071,353,886 - 71,617,666 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1071,353,886 - 71,558,246 (-)Ensemblpanpan1.1panPan2
MICU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1422,989,213 - 23,237,278 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl422,990,034 - 23,237,160 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha423,128,623 - 23,376,383 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0423,272,125 - 23,521,427 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl423,272,125 - 23,521,383 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1423,173,013 - 23,421,218 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0423,373,930 - 23,620,024 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0423,727,629 - 23,976,011 (-)NCBIUU_Cfam_GSD_1.0
Micu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721357,908,101 - 58,083,579 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365216,400,804 - 6,577,134 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365216,400,849 - 6,576,304 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MICU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1958,685,604 - 58,941,954 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl958,685,644 - 58,944,928 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604819,291,377 - 19,553,690 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Micu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247546,164,683 - 6,368,125 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247546,165,561 - 6,367,789 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MICU1
5379 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001243605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005671070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021071962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK236596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK391552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK393228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP144207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX916404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN152976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO954363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT956006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU607002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN117270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01061207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000011261   ⟹   ENSSSCP00000010969
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1475,203,752 - 75,445,626 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000047392   ⟹   ENSSSCP00000048813
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1475,203,749 - 75,445,546 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000050834   ⟹   ENSSSCP00000032388
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1475,203,752 - 75,445,626 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000065122   ⟹   ENSSSCP00000045487
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1475,203,736 - 75,445,618 (-)Ensembl
RefSeq Acc Id: NM_001243605   ⟹   NP_001230534
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,734 - 75,445,598 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005671067   ⟹   XP_005671124
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005671068   ⟹   XP_005671125
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005671069   ⟹   XP_005671126
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005671070   ⟹   XP_005671127
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021071958   ⟹   XP_020927617
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021071959   ⟹   XP_020927618
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021071961   ⟹   XP_020927620
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021071962   ⟹   XP_020927621
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11475,203,731 - 75,445,628 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020927621   ⟸   XM_021071962
- Peptide Label: isoform X8
- UniProtKB: A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671125   ⟸   XM_005671068
- Peptide Label: isoform X4
- UniProtKB: A0A287AXE8 (UniProtKB/TrEMBL),   A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671127   ⟸   XM_005671070
- Peptide Label: isoform X7
- UniProtKB: A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671124   ⟸   XM_005671067
- Peptide Label: isoform X3
- UniProtKB: A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005671126   ⟸   XM_005671069
- Peptide Label: isoform X6
- UniProtKB: A0A8D0TLK8 (UniProtKB/TrEMBL),   F1SU87 (UniProtKB/TrEMBL),   A0A8D0IN37 (UniProtKB/TrEMBL),   A0A8D0ISJ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020927618   ⟸   XM_021071959
- Peptide Label: isoform X2
- UniProtKB: A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020927620   ⟸   XM_021071961
- Peptide Label: isoform X5
- UniProtKB: A0A8D0IN84 (UniProtKB/TrEMBL),   A0A286ZLA2 (UniProtKB/TrEMBL),   A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020927617   ⟸   XM_021071958
- Peptide Label: isoform X1
- UniProtKB: A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230534   ⟸   NM_001243605
- UniProtKB: A0A8D0IGI3 (UniProtKB/TrEMBL),   A0A8D0IN37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000045487   ⟸   ENSSSCT00000065122
Ensembl Acc Id: ENSSSCP00000010969   ⟸   ENSSSCT00000011261
Ensembl Acc Id: ENSSSCP00000032388   ⟸   ENSSSCT00000050834
Ensembl Acc Id: ENSSSCP00000048813   ⟸   ENSSSCT00000047392
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005012936 UniProtKB/TrEMBL
  ENSSSCG00025076723 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011261 ENTREZGENE
  ENSSSCT00000011261.5 UniProtKB/TrEMBL
  ENSSSCT00000050834 ENTREZGENE
  ENSSSCT00000050834.3 UniProtKB/TrEMBL
  ENSSSCT00005021746.1 UniProtKB/TrEMBL
  ENSSSCT00005021780.1 UniProtKB/TrEMBL
  ENSSSCT00005021813.1 UniProtKB/TrEMBL
  ENSSSCT00005021857.1 UniProtKB/TrEMBL
  ENSSSCT00005021949.1 UniProtKB/TrEMBL
  ENSSSCT00025106351.1 UniProtKB/TrEMBL
  ENSSSCT00025106363.1 UniProtKB/TrEMBL
  ENSSSCT00025106378.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  MICU1/2/3 UniProtKB/TrEMBL
KEGG Report ssc:100155980 UniProtKB/TrEMBL
NCBI Gene MICU1 ENTREZGENE
PANTHER CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12294 UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A286ZLA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A287AXE8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IGI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IN37 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IN84 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IRX9_PIG UniProtKB/TrEMBL
  A0A8D0ISJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TLK8 ENTREZGENE, UniProtKB/TrEMBL
  F1SU87 ENTREZGENE
UniProt Secondary F1SU87 UniProtKB/TrEMBL
VGNC ID VGNC:90211 ENTREZGENE