MFNG (MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) - Rat Genome Database

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Gene: MFNG (MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) Sus scrofa
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Symbol: MFNG
Name: MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGD ID: 14179725
Description: ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity (inferred); INVOLVED IN blastocyst formation (ortholog); positive regulation of Notch signaling pathway (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); myoclonic dystonia 26 (ortholog); FOUND IN endomembrane system (inferred); Golgi apparatus (inferred); Golgi membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-1,3-N-acetylglucosaminyltransferase manic fringe
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,319,816 - 10,344,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,319,821 - 10,334,500 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,856,078 - 7,869,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MFNG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,319,816 - 10,344,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,319,821 - 10,334,500 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,856,078 - 7,869,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFNG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,469,063 - 37,486,384 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,469,063 - 37,486,393 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,865,101 - 37,882,422 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,195,049 - 36,212,331 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,189,602 - 36,206,885NCBI
Celera2221,665,904 - 21,683,281 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2220,831,325 - 20,848,704 (-)NCBIHuRef
CHM1_12237,823,899 - 37,841,275 (-)NCBICHM1_1
T2T-CHM13v2.02237,929,523 - 37,947,248 (-)NCBIT2T-CHM13v2.0
Mfng
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,640,082 - 78,657,678 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,640,082 - 78,657,675 (-)EnsemblGRCm39 Ensembl
GRCm381578,755,882 - 78,773,516 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,755,882 - 78,773,475 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,586,313 - 78,603,875 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,583,138 - 78,600,700 (-)NCBIMGSCv36mm8
Celera1580,221,888 - 80,237,486 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.69NCBI
Mfng
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,191,288 - 112,209,129 (-)NCBIGRCr8
mRatBN7.27110,310,810 - 110,328,653 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,310,812 - 110,328,653 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,061,715 - 112,079,333 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,285,241 - 114,302,863 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,252,907 - 114,270,641 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,978,981 - 119,996,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,978,983 - 119,996,824 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,970,579 - 119,988,416 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,717,405 - 116,735,280 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,751,634 - 116,769,510 (-)NCBI
Celera7106,646,792 - 106,664,572 (-)NCBICelera
Cytogenetic Map7q34NCBI
Mfng
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,902,707 - 23,917,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,901,987 - 23,917,720 (-)NCBIChiLan1.0ChiLan1.0
MFNG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,328,155 - 47,349,696 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,016,754 - 50,038,296 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,385,664 - 18,407,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,218,403 - 36,236,402 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,218,403 - 36,239,804 (-)Ensemblpanpan1.1panPan2
MFNG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,082,616 - 27,098,994 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,082,789 - 27,098,617 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,037,155 - 27,053,393 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,874,455 - 27,890,695 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,846,464 - 27,890,680 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,596,327 - 27,612,563 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,904,972 - 27,921,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,082,732 - 28,098,966 (+)NCBIUU_Cfam_GSD_1.0
Mfng
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,536,906 - 10,551,526 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,547,282 - 3,562,022 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,547,345 - 3,561,940 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFNG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,177,108 - 20,195,406 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,176,878 - 20,194,915 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045105,630,340 - 105,651,186 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mfng
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,394,008 - 10,412,412 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,394,025 - 10,411,265 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MFNG
677 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 22 3 2 5 14 12 22 3 5 3

Sequence


Ensembl Acc Id: ENSSSCT00000028424   ⟹   ENSSSCP00000021102
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,319,826 - 10,334,504 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000048312   ⟹   ENSSSCP00000049179
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,319,859 - 10,334,496 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000079378   ⟹   ENSSSCP00000067733
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,319,816 - 10,344,832 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000091201   ⟹   ENSSSCP00000072117
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl510,320,055 - 10,334,504 (+)Ensembl
RefSeq Acc Id: XM_021091517   ⟹   XP_020947176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1510,319,821 - 10,334,500 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020947176   ⟸   XM_021091517
- UniProtKB: A0A8D1D3K4 (UniProtKB/TrEMBL),   I3LAN4 (UniProtKB/TrEMBL),   A0A480VTE0 (UniProtKB/TrEMBL),   A0A8D1KIU6 (UniProtKB/TrEMBL),   A0A8D1TNV9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000067733   ⟸   ENSSSCT00000079378
Ensembl Acc Id: ENSSSCP00000072117   ⟸   ENSSSCT00000091201
Ensembl Acc Id: ENSSSCP00000021102   ⟸   ENSSSCT00000028424
Ensembl Acc Id: ENSSSCP00000049179   ⟸   ENSSSCT00000048312

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030209 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005004140 UniProtKB/TrEMBL
  ENSSSCG00025022991 UniProtKB/TrEMBL
  ENSSSCG00030001577 UniProtKB/TrEMBL
  ENSSSCG00035071411 UniProtKB/TrEMBL
  ENSSSCG00040064269 UniProtKB/TrEMBL
  ENSSSCG00045028496 UniProtKB/TrEMBL
  ENSSSCG00050071252 UniProtKB/TrEMBL
  ENSSSCG00055030214 UniProtKB/TrEMBL
  ENSSSCG00065023596 UniProtKB/TrEMBL
  ENSSSCG00070018443 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000028424 ENTREZGENE
  ENSSSCT00000028424.4 UniProtKB/TrEMBL
  ENSSSCT00000048312.3 UniProtKB/TrEMBL
  ENSSSCT00000079378.2 UniProtKB/TrEMBL
  ENSSSCT00000091201.2 UniProtKB/TrEMBL
  ENSSSCT00005006067.1 UniProtKB/TrEMBL
  ENSSSCT00005006130.1 UniProtKB/TrEMBL
  ENSSSCT00005006153.1 UniProtKB/TrEMBL
  ENSSSCT00005006185.1 UniProtKB/TrEMBL
  ENSSSCT00025031165.1 UniProtKB/TrEMBL
  ENSSSCT00025031195.1 UniProtKB/TrEMBL
  ENSSSCT00025031232.1 UniProtKB/TrEMBL
  ENSSSCT00030002045.1 UniProtKB/TrEMBL
  ENSSSCT00030002068.1 UniProtKB/TrEMBL
  ENSSSCT00030002090.1 UniProtKB/TrEMBL
  ENSSSCT00030002095.1 UniProtKB/TrEMBL
  ENSSSCT00035096537.1 UniProtKB/TrEMBL
  ENSSSCT00035096553.1 UniProtKB/TrEMBL
  ENSSSCT00035096571.1 UniProtKB/TrEMBL
  ENSSSCT00040087846.1 UniProtKB/TrEMBL
  ENSSSCT00040088033.1 UniProtKB/TrEMBL
  ENSSSCT00040088174.1 UniProtKB/TrEMBL
  ENSSSCT00040088255.1 UniProtKB/TrEMBL
  ENSSSCT00045048568.1 UniProtKB/TrEMBL
  ENSSSCT00045048686.1 UniProtKB/TrEMBL
  ENSSSCT00045048752.1 UniProtKB/TrEMBL
  ENSSSCT00045048846.1 UniProtKB/TrEMBL
  ENSSSCT00050097189.1 UniProtKB/TrEMBL
  ENSSSCT00055060117.1 UniProtKB/TrEMBL
  ENSSSCT00055060127.1 UniProtKB/TrEMBL
  ENSSSCT00055060131.1 UniProtKB/TrEMBL
  ENSSSCT00055060137.1 UniProtKB/TrEMBL
  ENSSSCT00065031399.1 UniProtKB/TrEMBL
  ENSSSCT00065031407.1 UniProtKB/TrEMBL
  ENSSSCT00065031411.1 UniProtKB/TrEMBL
  ENSSSCT00065031414.1 UniProtKB/TrEMBL
  ENSSSCT00070036545.1 UniProtKB/TrEMBL
  ENSSSCT00070036664.1 UniProtKB/TrEMBL
  ENSSSCT00070036777.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.50 UniProtKB/TrEMBL
InterPro Fringe UniProtKB/TrEMBL
  Fringe-like UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
NCBI Gene MFNG ENTREZGENE
PANTHER BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE UniProtKB/TrEMBL
  FRINGE-RELATED UniProtKB/TrEMBL
Pfam Fringe UniProtKB/TrEMBL
PIRSF B-acetylgalactosaminyltfrase UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A287AYF0_PIG UniProtKB/TrEMBL
  A0A480VTE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UMQ5_PIG UniProtKB/TrEMBL
  A0A4X1UPJ5_PIG UniProtKB/TrEMBL
  A0A4X1UQD1_PIG UniProtKB/TrEMBL
  A0A5G2RAU9_PIG UniProtKB/TrEMBL
  A0A5G2RCV3_PIG UniProtKB/TrEMBL
  A0A8D0HY24_PIG UniProtKB/TrEMBL
  A0A8D0HY62_PIG UniProtKB/TrEMBL
  A0A8D0I169_PIG UniProtKB/TrEMBL
  A0A8D0I1Y8_PIG UniProtKB/TrEMBL
  A0A8D0V5D8_PIG UniProtKB/TrEMBL
  A0A8D0V5E0_PIG UniProtKB/TrEMBL
  A0A8D0V5G3_PIG UniProtKB/TrEMBL
  A0A8D1BRT7_PIG UniProtKB/TrEMBL
  A0A8D1D3K4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1D3K6_PIG UniProtKB/TrEMBL
  A0A8D1FHS5_PIG UniProtKB/TrEMBL
  A0A8D1FJT3_PIG UniProtKB/TrEMBL
  A0A8D1II79_PIG UniProtKB/TrEMBL
  A0A8D1KIU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SH15_PIG UniProtKB/TrEMBL
  A0A8D1SJ99_PIG UniProtKB/TrEMBL
  A0A8D1TNV9 ENTREZGENE, UniProtKB/TrEMBL
  I3LAN4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:90180 ENTREZGENE