ZNF674 (zinc finger protein 674) - Rat Genome Database

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Gene: ZNF674 (zinc finger protein 674) Sus scrofa
Analyze
Symbol: ZNF674
Name: zinc finger protein 674
RGD ID: 14164593
Description: ENCODES a protein that exhibits DNA binding (inferred); zinc ion binding (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Kabuki Syndrome 2 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X41,090,146 - 41,118,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X45,932,252 - 45,961,282 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ZNF674
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X41,090,146 - 41,118,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X45,932,252 - 45,961,282 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF674
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X46,497,725 - 46,545,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX46,497,725 - 46,545,457 (-)EnsemblGRCh38hg38GRCh38
GRCh37X46,357,160 - 46,404,856 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,243,490 - 46,289,820 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX50,549,004 - 50,596,734 (-)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX44,070,196 - 44,117,151 (-)NCBIHuRef
CHM1_1X46,389,297 - 46,437,039 (-)NCBICHM1_1
T2T-CHM13v2.0X45,904,681 - 45,952,389 (-)NCBIT2T-CHM13v2.0
Zfp819
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,256,559 - 43,267,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,256,593 - 43,267,709 (+)EnsemblGRCm39 Ensembl
GRCm38743,607,135 - 43,618,279 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,607,169 - 43,618,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,862,539 - 50,873,649 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,475,267 - 43,486,321 (+)NCBIMGSCv36mm8
Celera739,071,267 - 39,082,376 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
ZNF674
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X48,125,894 - 48,174,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X48,129,269 - 48,177,438 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X38,935,585 - 38,983,728 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X46,799,224 - 46,846,082 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX46,799,224 - 46,846,082 (-)Ensemblpanpan1.1panPan2
ZNF674
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X40,146,143 - 40,179,963 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,122,425 - 40,153,968 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,122,425 - 40,153,968 (+)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX18,312,935 - 18,316,338 (+)NCBIDog10K_Boxer_Tasha
Dog10K_Boxer_TashaX18,329,445 - 18,340,770 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X40,280,697 - 40,313,898 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X40,263,524 - 40,303,118 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X40,257,022 - 40,290,166 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X40,343,231 - 40,382,854 (-)NCBIUU_Cfam_GSD_1.0
Znf674
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X32,529,841 - 32,532,008 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493650212,370,517 - 12,372,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF674
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X43,722,275 - 43,753,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660768,958,643 - 8,998,462 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf674
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248873,271,453 - 3,277,212 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZNF674
673 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


RefSeq Acc Id: XM_021080405   ⟹   XP_020936064
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X41,090,146 - 41,118,627 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021080406   ⟹   XP_020936065
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X41,090,174 - 41,118,627 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001422136 (Get FASTA)   NCBI Sequence Viewer  
  XP_020936064 (Get FASTA)   NCBI Sequence Viewer  
  XP_020936065 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000013051.4
  ENSSSCP00000034569.2
  ENSSSCP00000038804.1
  ENSSSCP00000038972.3
RefSeq Acc Id: XP_020936064   ⟸   XM_021080405
- Sequence:
RefSeq Acc Id: XP_020936065   ⟸   XM_021080406
- Sequence:
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012264 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013411.5 UniProtKB/TrEMBL
  ENSSSCT00000042539.3 UniProtKB/TrEMBL
  ENSSSCT00000051467.2 UniProtKB/TrEMBL
  ENSSSCT00000057216.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ZNF674 ENTREZGENE
PANTHER ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 715 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 717 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A286ZSL9_PIG UniProtKB/TrEMBL
  A0A287A4U8_PIG UniProtKB/TrEMBL
  A0A287A595_PIG UniProtKB/TrEMBL
  F1RWY4_PIG UniProtKB/TrEMBL