DBF4B (DBF4 zinc finger B) - Rat Genome Database

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Gene: DBF4B (DBF4 zinc finger B) Sus scrofa
Analyze
Symbol: DBF4B
Name: DBF4 zinc finger B
RGD ID: 14157785
Description: ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); protein kinase activator activity (inferred); INVOLVED IN positive regulation of cell population proliferation (inferred); positive regulation of G2/M transition of mitotic cell cycle (inferred); positive regulation of nuclear cell cycle DNA replication (inferred); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN chromatin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DBF4 homolog B; protein DBF4 homolog B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,603,797 - 18,630,543 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,602,218 - 18,640,216 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,971,049 - 18,996,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DBF4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,603,797 - 18,630,543 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,602,218 - 18,640,216 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,971,049 - 18,996,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DBF4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381744,708,665 - 44,752,264 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1744,708,608 - 44,752,264 (+)EnsemblGRCh38hg38GRCh38
GRCh371742,786,033 - 42,829,632 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,141,502 - 40,185,158 (+)NCBINCBI36Build 36hg18NCBI36
Celera1739,496,480 - 39,540,137 (+)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1738,550,812 - 38,594,994 (+)NCBIHuRef
CHM1_11743,022,108 - 43,065,804 (+)NCBICHM1_1
T2T-CHM13v2.01745,532,923 - 45,606,211 (+)NCBIT2T-CHM13v2.0
Gm39501
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,618,550 - 102,642,912 (+)NCBIGRCm39GRCm39mm39
GRCm3811102,727,724 - 102,752,086 (+)NCBIGRCm38GRCm38mm10GRCm38
Celera11114,437,632 - 114,464,278 (+)NCBICelera
Cytogenetic Map11E1NCBI
Dbf4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81088,209,913 - 88,219,336 (+)NCBIGRCr8
mRatBN7.21087,713,805 - 87,719,197 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.01090,710,468 - 90,723,313 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01090,487,369 - 90,513,113 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1086,411,642 - 86,422,960 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
DBF4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21920,082,621 - 20,126,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11722,043,809 - 22,097,906 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,571,265 - 12,616,105 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,744,110 - 12,790,302 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,744,297 - 12,790,089 (-)Ensemblpanpan1.1panPan2
DBF4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1918,734,678 - 18,768,128 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,119,978 - 18,155,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,428,782 - 19,464,638 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,428,787 - 19,462,537 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1918,282,336 - 18,315,731 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,464,525 - 18,499,866 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0918,621,510 - 18,654,920 (-)NCBIUU_Cfam_GSD_1.0
Dbf4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560218,061,389 - 18,087,491 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365411,108,577 - 1,133,203 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103243316
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,652,845 - 61,693,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607732,405,466 - 32,448,093 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in DBF4B
1134 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 22 3 2 5 13 12 22 2 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000040470   ⟹   ENSSSCP00000034830
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1218,611,898 - 18,630,465 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000058135   ⟹   ENSSSCP00000040277
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1218,603,797 - 18,630,543 (-)Ensembl
RefSeq Acc Id: XM_021066859   ⟹   XP_020922518
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11218,602,218 - 18,640,216 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021066860   ⟹   XP_020922519
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11218,602,218 - 18,640,216 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020922518 (Get FASTA)   NCBI Sequence Viewer  
  XP_020922519 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000040277
  ENSSSCP00000040277.1
  ENSSSCP00025032760.1
  ENSSSCP00045017504.1
  ENSSSCP00055031376.1
  ENSSSCP00065019480.1
RefSeq Acc Id: XP_020922519   ⟸   XM_021066860
- Peptide Label: isoform X2
- UniProtKB: A0A8D0SRQ0 (UniProtKB/TrEMBL),   A0A8D1R3V7 (UniProtKB/TrEMBL),   A0A8D1YF88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020922518   ⟸   XM_021066859
- Peptide Label: isoform X1
- UniProtKB: A0A287A8H0 (UniProtKB/TrEMBL),   A0A8D0SRQ0 (UniProtKB/TrEMBL),   A0A8D1R3V7 (UniProtKB/TrEMBL),   A0A8D1YF88 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000034830   ⟸   ENSSSCT00000040470
Ensembl Acc Id: ENSSSCP00000040277   ⟸   ENSSSCT00000058135
Protein Domains
DBF4-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037238 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025055271 UniProtKB/TrEMBL
  ENSSSCG00045014947 UniProtKB/TrEMBL
  ENSSSCG00055020130 UniProtKB/TrEMBL
  ENSSSCG00065033435 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000058135 ENTREZGENE
  ENSSSCT00000058135.2 UniProtKB/TrEMBL
  ENSSSCT00025075575.1 UniProtKB/TrEMBL
  ENSSSCT00045025360.1 UniProtKB/TrEMBL
  ENSSSCT00055039445.1 UniProtKB/TrEMBL
  ENSSSCT00065045430.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.40 UniProtKB/TrEMBL
  6.10.250.3410 UniProtKB/TrEMBL
InterPro Replication_Regulatory_Kinase UniProtKB/TrEMBL
  Znf_DBF UniProtKB/TrEMBL
  Znf_DBF_sf UniProtKB/TrEMBL
NCBI Gene DBF4B ENTREZGENE
PANTHER ACTIVATOR OF S-PHASE KINASE-RELATED UniProtKB/TrEMBL
  PROTEIN DBF4 HOMOLOG B UniProtKB/TrEMBL
Pfam zf-DBF UniProtKB/TrEMBL
PROSITE ZF_DBF4 UniProtKB/TrEMBL
SMART ZnF_DBF UniProtKB/TrEMBL
UniProt A0A287A8H0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0SRQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1R3V7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1YF88 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:98984 ENTREZGENE