ELL2 (elongation factor for RNA polymerase II 2) - Rat Genome Database

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Gene: ELL2 (elongation factor for RNA polymerase II 2) Sus scrofa
Analyze
Symbol: ELL2
Name: elongation factor for RNA polymerase II 2
RGD ID: 14121557
Description: ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (inferred); translation elongation factor activity (inferred); INVOLVED IN positive regulation of transcription elongation by RNA polymerase II (inferred); snRNA transcription by RNA polymerase II (inferred); transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH COVID-19 (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); transcription elongation factor complex (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RNA polymerase II elongation factor ELL2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2102,518,608 - 102,591,394 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12102,518,605 - 102,591,416 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22106,402,543 - 106,475,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ELL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2102,518,608 - 102,591,394 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12102,518,605 - 102,591,416 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22106,402,543 - 106,475,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38595,885,098 - 95,961,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl595,885,098 - 95,961,851 (-)EnsemblGRCh38hg38GRCh38
GRCh37595,220,802 - 95,297,555 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36595,246,558 - 95,323,531 (-)NCBINCBI36Build 36hg18NCBI36
Build 34595,248,856 - 95,323,531NCBI
Celera591,099,569 - 91,176,577 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef590,411,375 - 90,488,473 (-)NCBIHuRef
CHM1_1594,653,611 - 94,730,421 (-)NCBICHM1_1
T2T-CHM13v2.0596,386,338 - 96,463,172 (-)NCBIT2T-CHM13v2.0
Ell2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391375,855,603 - 75,920,480 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1375,854,876 - 75,920,483 (+)EnsemblGRCm39 Ensembl
GRCm381375,707,484 - 75,772,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1375,706,757 - 75,772,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371375,844,932 - 75,909,809 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361376,172,805 - 76,238,363 (+)NCBIMGSCv36mm8
Celera1378,027,359 - 78,092,187 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.93NCBI
Ell2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr826,910,446 - 6,990,654 (+)NCBIGRCr8
mRatBN7.225,189,375 - 5,258,781 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl25,189,971 - 5,258,781 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.022,456,189 - 2,525,590 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl22,456,735 - 2,524,237 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.022,449,357 - 2,519,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.422,724,984 - 2,794,397 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.122,745,161 - 2,813,837 (+)NCBI
Celera21,661,941 - 1,730,615 (+)NCBICelera
Cytogenetic Map2q11NCBI
Ell2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541816,614,543 - 16,687,698 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541816,615,340 - 16,686,632 (+)NCBIChiLan1.0ChiLan1.0
ELL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2419,406,161 - 19,494,138 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1517,571,196 - 17,645,446 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0519,387,443 - 19,464,150 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1519,533,442 - 19,610,079 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl519,533,442 - 19,610,079 (+)Ensemblpanpan1.1panPan2
ELL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1313,673,653 - 13,746,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl313,673,785 - 13,746,316 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha315,012,972 - 15,085,860 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0313,553,675 - 13,626,554 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl313,553,644 - 13,624,274 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1313,516,603 - 13,589,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0313,513,473 - 13,586,474 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0313,713,306 - 13,786,243 (+)NCBIUU_Cfam_GSD_1.0
Ell2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,213,989 - 169,285,468 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365237,399,421 - 7,473,158 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365237,399,426 - 7,470,895 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1489,758,483 - 89,835,773 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl489,762,251 - 89,835,433 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604938,404,258 - 38,481,671 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ell2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474314,515,727 - 14,583,805 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ELL2
1220 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 1 3 4 1 12 2 1 3
Low 4 3 1 1 11 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000054141   ⟹   ENSSSCP00000037643
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2102,518,608 - 102,591,394 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000102858   ⟹   ENSSSCP00000080686
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2102,522,050 - 102,591,390 (-)Ensembl
RefSeq Acc Id: XM_003123796   ⟹   XP_003123844
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12102,518,605 - 102,591,416 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003123844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000037643.3
  ENSSSCP00000080686
  ENSSSCP00000080686.1
  ENSSSCP00015016365.1
  ENSSSCP00070015407.1
Reference Protein Sequences
RefSeq Acc Id: XP_003123844   ⟸   XM_003123796
- UniProtKB: A0A480JTG5 (UniProtKB/TrEMBL),   A0A8D0NBL7 (UniProtKB/TrEMBL),   A0A4X1TK81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000037643   ⟸   ENSSSCT00000054141
RefSeq Acc Id: ENSSSCP00000080686   ⟸   ENSSSCT00000102858
Protein Domains
OCEL


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000014168 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015031162 UniProtKB/TrEMBL
  ENSSSCG00070009554 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000054141.3 UniProtKB/TrEMBL
  ENSSSCT00000102858 ENTREZGENE
  ENSSSCT00000102858.1 UniProtKB/TrEMBL
  ENSSSCT00015041402.1 UniProtKB/TrEMBL
  ENSSSCT00070018539.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2670 UniProtKB/TrEMBL
  6.10.140.340 UniProtKB/TrEMBL
InterPro E3_ELL-like UniProtKB/TrEMBL
  ELL/occludin UniProtKB/TrEMBL
  ELL_N UniProtKB/TrEMBL
  Occludin_ELL UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report ssc:100523777 UniProtKB/TrEMBL
NCBI Gene ELL2 ENTREZGENE
PANTHER PTHR23288 UniProtKB/TrEMBL
  RNA POLYMERASE II ELONGATION FACTOR ELL2 UniProtKB/TrEMBL
Pfam ELL UniProtKB/TrEMBL
  Occludin_ELL UniProtKB/TrEMBL
PROSITE OCEL UniProtKB/TrEMBL
Superfamily-SCOP occludin/ELL-like UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A287A147_PIG UniProtKB/TrEMBL
  A0A480JTG5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TK81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NBL7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:87649 ENTREZGENE