SPAG8 (sperm associated antigen 8) - Rat Genome Database

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Gene: SPAG8 (sperm associated antigen 8) Sus scrofa
Analyze
Symbol: SPAG8
Name: sperm associated antigen 8
RGD ID: 14063062
Description: ENCODES a protein that exhibits catalytic activity (inferred); microtubule binding (inferred); INVOLVED IN flagellated sperm motility (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); anauxetic dysplasia (ortholog); autosomal recessive distal hereditary motor neuronopathy 2 (ortholog); FOUND IN axonemal A tubule inner sheath (ortholog); cytoplasm (ortholog); male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sperm-associated antigen 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,529,269 - 236,534,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,526,659 - 236,532,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,254,276 - 264,257,231 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPAG8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,529,269 - 236,534,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,526,659 - 236,532,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,254,276 - 264,257,231 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPAG8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,807,785 - 35,812,262 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,808,045 - 35,812,272 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,807,782 - 35,812,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,797,782 - 35,802,259 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,797,781 - 35,802,259NCBI
Celera935,741,314 - 35,745,791 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,763,806 - 35,768,271 (-)NCBIHuRef
CHM1_1935,808,170 - 35,812,647 (-)NCBICHM1_1
T2T-CHM13v2.0935,828,452 - 35,832,929 (-)NCBIT2T-CHM13v2.0
Spag8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,651,330 - 43,653,594 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,651,335 - 43,653,594 (-)EnsemblGRCm39 Ensembl
GRCm38443,651,330 - 43,653,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,651,335 - 43,653,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv37443,664,601 - 43,666,424 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,672,829 - 43,674,652 (-)NCBIMGSCv36mm8
Celera443,686,334 - 43,688,157 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.05NCBI
Spag8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,697,451 - 62,699,664 (-)NCBIGRCr8
mRatBN7.2557,901,681 - 57,903,894 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,901,682 - 57,903,894 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,881,766 - 59,883,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,700,580 - 61,702,793 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,671,784 - 61,674,016 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,147,412 - 59,149,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,147,337 - 59,149,699 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,672,204 - 63,674,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,128,061 - 60,130,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,128,239 - 60,130,453 (-)NCBI
Celera556,482,149 - 56,484,362 (-)NCBICelera
Cytogenetic Map5q22NCBI
Spag8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955472504,087 - 505,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955472503,286 - 506,261 (+)NCBIChiLan1.0ChiLan1.0
SPAG8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21188,776,425 - 88,781,041 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1988,782,356 - 88,787,361 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0935,658,541 - 35,662,920 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1936,460,951 - 36,465,112 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,460,951 - 36,465,112 (-)Ensemblpanpan1.1panPan2
SPAG8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,339,338 - 52,341,642 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,339,339 - 52,341,522 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,906,909 - 50,909,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01153,404,355 - 53,406,659 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1153,404,356 - 53,406,539 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,948,863 - 51,951,167 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,933,087 - 51,935,391 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,634,545 - 52,636,849 (-)NCBIUU_Cfam_GSD_1.0
Spag8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,214,302 - 167,253,806 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365243,798,281 - 3,800,704 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365243,798,144 - 3,801,479 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPAG8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,792,661 - 44,795,736 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1244,793,253 - 44,800,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603841,897,315 - 41,900,388 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spag8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248684,972,286 - 4,974,442 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248684,971,510 - 4,974,601 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPAG8
110 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000005862   ⟹   ENSSSCP00000005717
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1236,529,262 - 236,534,447 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000026395   ⟹   ENSSSCP00000026114
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1236,529,269 - 236,532,876 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000042735   ⟹   ENSSSCP00000052977
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1236,529,361 - 236,531,520 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000100991   ⟹   ENSSSCP00000077050
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1236,531,402 - 236,534,734 (-)Ensembl
RefSeq Acc Id: XM_005660229   ⟹   XP_005660286
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11236,526,659 - 236,532,181 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005660286 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000026114.4
  ENSSSCP00000052977
  ENSSSCP00000052977.3
  ENSSSCP00000077050.1
  ENSSSCP00035022350.1
  ENSSSCP00065032071.1
RefSeq Acc Id: XP_005660286   ⟸   XM_005660229
- UniProtKB: A0A480VJN4 (UniProtKB/TrEMBL),   A0A287BA79 (UniProtKB/TrEMBL),   A0A8D0ZRA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000005717   ⟸   ENSSSCT00000005862
Ensembl Acc Id: ENSSSCP00000026114   ⟸   ENSSSCT00000026395
Ensembl Acc Id: ENSSSCP00000052977   ⟸   ENSSSCT00000042735
Ensembl Acc Id: ENSSSCP00000077050   ⟸   ENSSSCT00000100991
Protein Domains
HIT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00035041806 UniProtKB/TrEMBL
  ENSSSCG00065053777 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026395.4 UniProtKB/TrEMBL
  ENSSSCT00000042735 ENTREZGENE
  ENSSSCT00000042735.3 UniProtKB/TrEMBL
  ENSSSCT00000100991.1 UniProtKB/TrEMBL
  ENSSSCT00035055566.1 UniProtKB/TrEMBL
  ENSSSCT00065073655.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.428.10 UniProtKB/TrEMBL
InterPro Histidine_triad_HIT UniProtKB/TrEMBL
  HIT-like UniProtKB/TrEMBL
  HIT-like_sf UniProtKB/TrEMBL
  Sperm-assoc_Ag8 UniProtKB/TrEMBL
KEGG Report ssc:100513194 UniProtKB/TrEMBL
NCBI Gene SPAG8 ENTREZGENE
PANTHER HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR15510 UniProtKB/TrEMBL
  PTHR23089 UniProtKB/TrEMBL
  SPERM-ASSOCIATED ANTIGEN 8 UniProtKB/TrEMBL
Pfam CFAP143 UniProtKB/TrEMBL
  DcpS_C UniProtKB/TrEMBL
PRINTS HISTRIAD UniProtKB/TrEMBL
PROSITE HIT_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF54197 UniProtKB/TrEMBL
UniProt A0A287BA79 ENTREZGENE, UniProtKB/TrEMBL
  A0A480VJN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZRA4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FDW8_PIG UniProtKB/TrEMBL
  I3LPT7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:93373 ENTREZGENE