ZKSCAN4 (zinc finger with KRAB and SCAN domains 4) - Rat Genome Database

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Gene: ZKSCAN4 (zinc finger with KRAB and SCAN domains 4) Sus scrofa
Analyze
Symbol: ZKSCAN4
Name: zinc finger with KRAB and SCAN domains 4
RGD ID: 14033910
Description: ENCODES a protein that exhibits DNA binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); ASSOCIATED WITH megacolon (ortholog); schizophrenia (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein 187; zinc finger protein with KRAB and SCAN domains 4; ZNF187
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,093,059 - 22,101,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,092,465 - 22,105,666 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,036,992 - 24,076,992 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
megacolon  (ISO)
schizophrenia  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ZKSCAN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,093,059 - 22,101,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,092,465 - 22,105,666 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,036,992 - 24,076,992 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZKSCAN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38628,241,697 - 28,259,211 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl628,241,697 - 28,252,269 (-)EnsemblGRCh38hg38GRCh38
GRCh37628,209,475 - 28,226,989 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36628,320,469 - 28,327,981 (-)NCBINCBI36Build 36hg18NCBI36
Build 34628,320,468 - 28,327,981NCBI
Celera629,818,944 - 29,826,449 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef628,020,146 - 28,027,658 (-)NCBIHuRef
CHM1_1628,214,857 - 28,222,369 (-)NCBICHM1_1
T2T-CHM13v2.0628,113,435 - 28,131,010 (-)NCBIT2T-CHM13v2.0
Zkscan4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,663,019 - 21,669,677 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,663,019 - 21,669,677 (+)EnsemblGRCm39 Ensembl
GRCm381321,478,849 - 21,485,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,478,907 - 21,485,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv371321,570,776 - 21,577,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,486,372 - 21,492,972 (+)NCBIMGSCv36mm8
Celera1321,746,573 - 21,753,173 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.82NCBI
Zkscan4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81747,800,586 - 47,808,833 (-)NCBIGRCr8
mRatBN7.21743,104,853 - 43,113,101 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,106,370 - 43,113,183 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01745,144,000 - 45,154,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,148,646 - 45,154,355 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01758,313,739 - 58,324,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41750,749,545 - 50,755,739 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11750,752,385 - 50,758,580 (-)NCBI
Celera1753,354,175 - 53,365,001 (+)NCBICelera
Cytogenetic Map17p11NCBI
Zkscan4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546513,611,669 - 13,617,147 (-)NCBIChiLan1.0ChiLan1.0
ZKSCAN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2542,860,529 - 42,868,467 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1638,857,773 - 38,869,304 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0628,043,634 - 28,061,996 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1628,717,815 - 28,734,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl628,718,522 - 28,727,201 (-)Ensemblpanpan1.1panPan2
ZKSCAN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13525,381,935 - 25,389,116 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3525,240,000 - 25,247,506 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03525,679,900 - 25,687,410 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13525,344,749 - 25,352,253 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03525,397,766 - 25,405,288 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03526,866,173 - 26,873,685 (-)NCBIUU_Cfam_GSD_1.0
Zkscan4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494628,669,849 - 28,678,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936772107,416 - 115,613 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936772107,462 - 116,211 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZKSCAN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11744,329,910 - 44,338,737 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604427,903,118 - 27,914,674 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZKSCAN4
532 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000001302   ⟹   ENSSSCP00000001273
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,093,059 - 22,101,839 (+)Ensembl
RefSeq Acc Id: XM_021099807   ⟹   XP_020955466
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,092,465 - 22,105,666 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099808   ⟹   XP_020955467
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,093,776 - 22,105,666 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020955466 (Get FASTA)   NCBI Sequence Viewer  
  XP_020955467 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000001273
  ENSSSCP00000001273.3
  ENSSSCP00005003158.1
  ENSSSCP00015030125.1
  ENSSSCP00055009042.1
  ENSSSCP00060016093.1
RefSeq Acc Id: XP_020955466   ⟸   XM_021099807
- Peptide Label: isoform X1
- UniProtKB: F1S1S1 (UniProtKB/TrEMBL),   A0A8D0P8S4 (UniProtKB/TrEMBL),   A0A8D1PUK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020955467   ⟸   XM_021099808
- Peptide Label: isoform X2
- UniProtKB: A0A8D0LE46 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000001273   ⟸   ENSSSCT00000001302
Protein Domains
C2H2-type   SCAN box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001204 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005003710 UniProtKB/TrEMBL
  ENSSSCG00015056389 UniProtKB/TrEMBL
  ENSSSCG00055005876 UniProtKB/TrEMBL
  ENSSSCG00060027955 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001302 ENTREZGENE
  ENSSSCT00000001302.5 UniProtKB/TrEMBL
  ENSSSCT00005005502.1 UniProtKB/TrEMBL
  ENSSSCT00015075098.1 UniProtKB/TrEMBL
  ENSSSCT00055011437.1 UniProtKB/TrEMBL
  ENSSSCT00060037827.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.4020.10 UniProtKB/TrEMBL
  6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  SCAN_dom UniProtKB/TrEMBL
  SCAN_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ZKSCAN4 ENTREZGENE
PANTHER FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 22 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  SCAN UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE SCAN_BOX UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  SCAN UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Retrovirus capsid dimerization domain-like UniProtKB/TrEMBL
  SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8D0LE46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0P8S4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PUK8 ENTREZGENE, UniProtKB/TrEMBL
  F1S1S1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95173 ENTREZGENE