TYW1 (tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TYW1 (tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)) Sus scrofa
Analyze
Symbol: TYW1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
RGD ID: 13910861
Description: ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); calcium ion binding (inferred); catalytic activity (inferred); INVOLVED IN tRNA processing (inferred); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); Golgi apparatus (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA wybutosine-synthesizing protein 1 homolog
RGD Orthologs
Human
Mouse
Rat
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1315,969,573 - 16,160,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2316,268,153 - 16,407,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TYW1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1315,969,573 - 16,160,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2316,268,153 - 16,407,307 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TYW1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38766,996,833 - 67,239,514 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl766,995,173 - 67,239,514 (+)EnsemblGRCh38hg38GRCh38
GRCh37766,461,820 - 66,704,501 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36766,099,252 - 66,341,934 (+)NCBINCBI36Build 36hg18NCBI36
Build 34765,905,966 - 66,148,646NCBI
Celera765,404,719 - 65,654,392 (-)NCBICelera
Cytogenetic Map7q11.21NCBI
HuRef762,645,117 - 62,888,045 (+)NCBIHuRef
CHM1_1766,557,015 - 66,797,606 (+)NCBICHM1_1
T2T-CHM13v2.0768,216,506 - 68,459,212 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2765,799,354 - 66,042,069 (+)NCBI
Tyw1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395130,284,460 - 130,370,408 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5130,284,460 - 130,370,404 (+)EnsemblGRCm39 Ensembl
GRCm385130,255,572 - 130,341,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5130,255,619 - 130,341,563 (+)EnsemblGRCm38mm10GRCm38
MGSCv375130,731,489 - 130,817,437 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365130,540,322 - 130,625,860 (+)NCBIMGSCv36mm8
Celera5127,268,547 - 127,354,754 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map569.0NCBI
Tyw1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81231,968,198 - 32,054,454 (-)NCBIGRCr8
mRatBN7.21226,332,020 - 26,418,286 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,330,351 - 26,418,208 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1227,480,231 - 27,566,470 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,090,756 - 28,176,978 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,149,061 - 27,235,174 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01229,824,990 - 29,919,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1229,824,981 - 29,919,320 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01231,761,916 - 31,856,112 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01231,135,209 - 31,178,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,368,907 - 27,455,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11227,232,122 - 27,318,272 (-)NCBI
Celera1228,046,508 - 28,132,529 (-)NCBICelera
Cytogenetic Map12q12NCBI
LOC479708
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.161,263,661 - 1,502,800 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha62,963,338 - 3,202,262 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.061,068,769 - 1,314,298 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.161,003,760 - 1,243,099 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.061,005,554 - 1,251,074 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.061,177,346 - 1,423,042 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in TYW1
8469 total Variants

Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003481010   ⟹   XP_003481058
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1316,017,973 - 16,160,652 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086356   ⟹   XP_020942015
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1316,003,433 - 16,160,652 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086357   ⟹   XP_020942016
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1315,969,573 - 16,160,652 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020942016   ⟸   XM_021086357
- Peptide Label: isoform X3
- UniProtKB: A0A8D1MPC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020942015   ⟸   XM_021086356
- Peptide Label: isoform X2
- UniProtKB: A0A8D1MPC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003481058   ⟸   XM_003481010
- Peptide Label: isoform X1
- UniProtKB: A0A8D1R1C6 (UniProtKB/TrEMBL),   A0A8D0SSZ8 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Flavodoxin-like   Radical SAM core


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007733 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025060086 UniProtKB/TrEMBL
  ENSSSCG00040034526 UniProtKB/TrEMBL
  ENSSSCG00050047224 UniProtKB/TrEMBL
  ENSSSCG00055017784 UniProtKB/TrEMBL
  ENSSSCG00065075324 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008475.5 UniProtKB/TrEMBL
  ENSSSCT00000008478.5 UniProtKB/TrEMBL
  ENSSSCT00000065883 ENTREZGENE
  ENSSSCT00000065883.3 UniProtKB/TrEMBL
  ENSSSCT00000078596.1 UniProtKB/TrEMBL
  ENSSSCT00000089284.2 UniProtKB/TrEMBL
  ENSSSCT00025083048.1 UniProtKB/TrEMBL
  ENSSSCT00040046448.1 UniProtKB/TrEMBL
  ENSSSCT00050064354.1 UniProtKB/TrEMBL
  ENSSSCT00050064369.1 UniProtKB/TrEMBL
  ENSSSCT00055035401.1 UniProtKB/TrEMBL
  ENSSSCT00065103966.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  3.40.50.360 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  Ca-binding_regulatory UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/TrEMBL
  rSAM UniProtKB/TrEMBL
  S100/CaBP7/8-like_CS UniProtKB/TrEMBL
  tRNA_wybutosine-synth UniProtKB/TrEMBL
  tRNA_wybutosine-synthase UniProtKB/TrEMBL
KEGG Report ssc:100516854 UniProtKB/TrEMBL
NCBI Gene TYW1 ENTREZGENE
PANTHER CALCIUM-BINDING PROTEIN 8 UniProtKB/TrEMBL
  CALCIUM-BINDING PROTEIN 8-RELATED UniProtKB/TrEMBL
  PTHR13930 UniProtKB/TrEMBL
  S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  Flavodoxin_1 UniProtKB/TrEMBL
  Radical_SAM UniProtKB/TrEMBL
  Wyosine_form UniProtKB/TrEMBL
PRINTS FLAVODOXIN UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  FLAVODOXIN_LIKE UniProtKB/TrEMBL
  RADICAL_SAM UniProtKB/TrEMBL
  S100_CABP UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP Radical SAM enzymes UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF52218 UniProtKB/TrEMBL
UniProt A0A287AAJ1_PIG UniProtKB/TrEMBL
  A0A4X1SU95_PIG UniProtKB/TrEMBL
  A0A5G2QAU9_PIG UniProtKB/TrEMBL
  A0A5G2R9F4_PIG UniProtKB/TrEMBL
  A0A8D0SSZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1MPC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1R1C6 ENTREZGENE, UniProtKB/TrEMBL
  F1RJJ2_PIG UniProtKB/TrEMBL
UniProt Secondary F1RJJ5 UniProtKB/TrEMBL