FCGR1BP (Fc gamma receptor Ib, pseudogene) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: FCGR1BP (Fc gamma receptor Ib, pseudogene) Homo sapiens
Analyze
No known orthologs.
Symbol: FCGR1BP
Name: Fc gamma receptor Ib, pseudogene
RGD ID: 1349361
HGNC Page HGNC:3614
Description: Predicted to enable IgG receptor activity. Predicted to be involved in antibody-dependent cellular cytotoxicity and cell surface receptor signaling pathway. Predicted to be located in clathrin-coated endocytic vesicle membrane; early endosome membrane; and plasma membrane. Predicted to be active in external side of plasma membrane.
Type: pseudo (Ensembl: transcribed_unprocessed_pseudogene)
RefSeq Status: REVIEWED
Previously known as: CD34; CD64; CD64b; Fc fragment of IgG receptor Ib; Fc fragment of IgG, high affinity Ib, receptor (CD64); Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fc gamma receptor I; Fc gamma receptor Ib; Fc-gamma receptor I B2; Fc-gamma RI; Fc-gamma RIA; fc-gamma RIB; FCG1; FcgammaRIa; FCGR1; FCGR1A; FCGR1B; FcRI; fcRIB; hFcgammaRIB; High affinity immunoglobulin gamma Fc receptor I; high affinity immunoglobulin gamma Fc receptor IB; IGFR1; IGFRB; IgG Fc receptor I; igG Fc receptor IB
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: FCGR1A  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381121,087,345 - 121,097,161 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1121,087,395 - 121,096,152 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1121,042,602 - 121,103,109 (+)EnsemblGRCh38hg38GRCh38
GRCh371120,926,128 - 120,935,944 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,728,657 - 120,737,417 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1p11.2NCBI
HuRef1118,453,001 - 118,453,262 (-)NCBIHuRef
CHM1_11121,745,435 - 121,755,251 (+)NCBICHM1_1
T2T-CHM13v2.01121,096,728 - 121,106,544 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1. Maresco DL, etal., Cytogenet Cell Genet 1998;82(1-2):71-4.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1379234   PMID:1402657   PMID:1430234   PMID:1830050   PMID:8697799   PMID:8889548   PMID:9232445   PMID:9490697   PMID:9881690   PMID:9933095   PMID:11802953   PMID:12477932  
PMID:12766061   PMID:17124586   PMID:19330030   PMID:21135020   PMID:21832933   PMID:21873635   PMID:32073518   PMID:34373451   PMID:35381635   PMID:35906200  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p12-q21.2(chr1:120836007-149583533)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051844]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051844]|See cases [RCV000051844] Chr1:120836007..149583533 [GRCh38]
Chr1:145425395..153212501 [GRCh37]
Chr1:144136752..151479125 [NCBI36]
Chr1:1p12-q21.2
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1428
Count of miRNA genes:537
Interacting mature miRNAs:600
Transcripts:ENST00000369178, ENST00000369383, ENST00000369384, ENST00000466915, ENST00000471609, ENST00000472543
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300021BP45_HBlood pressure QTL 45 (human)1.770.00218Blood pressuresystolic1103389009129389009Human

Markers in Region
GDB:190043  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,370,603 - 149,370,937UniSTSGRCh37
GRCh371149,755,559 - 149,755,893UniSTSGRCh37
Build 361147,637,227 - 147,637,561RGDNCBI36
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map1p11.2UniSTS
D1S3356  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map1p11.2UniSTS
Whitehead-RH Map1570.4UniSTS
Whitehead-YAC Contig Map1 UniSTS
RH69162  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map1p11.2UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1190 2138 2358 2134 4338 1656 2144 5 565 1387 410 1710 6130 5691 6 3639 773 1606 1474 163

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_045213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_164760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC244453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL357493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW134502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM992325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ030076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU682943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD677904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L03419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L03420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000369178   ⟹   ENSP00000481411
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,322 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000369383   ⟹   ENSP00000358390
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,300 - 121,097,161 (+)Ensembl
Ensembl Acc Id: ENST00000369384   ⟹   ENSP00000358391
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,295 - 121,097,161 (+)Ensembl
Ensembl Acc Id: ENST00000453173
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,262 - 121,096,304 (+)Ensembl
Ensembl Acc Id: ENST00000466915
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,304 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000471609
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,095,642 (+)Ensembl
Ensembl Acc Id: ENST00000472543   ⟹   ENSP00000479641
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,301 - 121,096,322 (+)Ensembl
Ensembl Acc Id: ENST00000615565
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,362 - 121,093,801 (+)Ensembl
Ensembl Acc Id: ENST00000616817   ⟹   ENSP00000478655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,095,642 (+)Ensembl
Ensembl Acc Id: ENST00000623603   ⟹   ENSP00000485498
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,095,642 (+)Ensembl
Ensembl Acc Id: ENST00000697334
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,395 - 121,096,152 (+)Ensembl
Ensembl Acc Id: ENST00000697335
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,311 - 121,091,051 (+)Ensembl
Ensembl Acc Id: ENST00000697336
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,372 - 121,096,308 (+)Ensembl
Ensembl Acc Id: ENST00000700794
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,328 - 121,096,389 (+)Ensembl
Ensembl Acc Id: ENST00000700943
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,331 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000700986
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,302 - 121,096,318 (+)Ensembl
Ensembl Acc Id: ENST00000701453
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,341 - 121,096,322 (+)Ensembl
Ensembl Acc Id: ENST00000701628
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,334 - 121,096,312 (+)Ensembl
Ensembl Acc Id: ENST00000701713
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,311 - 121,096,381 (+)Ensembl
Ensembl Acc Id: ENST00000701949
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,331 - 121,096,381 (+)Ensembl
Ensembl Acc Id: ENST00000702526
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,331 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000702760
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,096,307 (+)Ensembl
Ensembl Acc Id: ENST00000702854
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768787
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,042,602 - 121,095,954 (+)Ensembl
Ensembl Acc Id: ENST00000768788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,043,141 - 121,095,993 (+)Ensembl
Ensembl Acc Id: ENST00000768789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,044,011 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768790
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,044,098 - 121,096,314 (+)Ensembl
Ensembl Acc Id: ENST00000768791
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,044,110 - 121,096,308 (+)Ensembl
Ensembl Acc Id: ENST00000768792
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,050,340 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768793
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,043,125 - 121,088,030 (+)Ensembl
Ensembl Acc Id: ENST00000768794
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,364 - 121,103,109 (+)Ensembl
Ensembl Acc Id: ENST00000768795
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,369 - 121,102,514 (+)Ensembl
Ensembl Acc Id: ENST00000768796
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,311 - 121,096,425 (+)Ensembl
Ensembl Acc Id: ENST00000768797
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,364 - 121,096,317 (+)Ensembl
Ensembl Acc Id: ENST00000768798
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,364 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768799
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,369 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768800
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,372 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768801
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,372 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768802
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,369 - 121,096,304 (+)Ensembl
Ensembl Acc Id: ENST00000768803
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,399 - 121,095,992 (+)Ensembl
Ensembl Acc Id: ENST00000768804
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,769 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768805
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,802 - 121,095,982 (+)Ensembl
Ensembl Acc Id: ENST00000768806
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,044,121 - 121,051,846 (+)Ensembl
Ensembl Acc Id: ENST00000768807
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,328 - 121,094,068 (+)Ensembl
Ensembl Acc Id: ENST00000768808
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,364 - 121,096,310 (+)Ensembl
Ensembl Acc Id: ENST00000768810
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,050,270 - 121,051,926 (+)Ensembl
Ensembl Acc Id: ENST00000768811
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1121,087,345 - 121,088,552 (+)Ensembl
RefSeq Acc Id: NR_045213
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381121,087,345 - 121,097,161 (+)NCBI
GRCh371120,926,128 - 120,935,944 (-)NCBI
HuRef1118,453,001 - 118,453,262 (-)NCBI
CHM1_11121,745,435 - 121,755,251 (+)NCBI
T2T-CHM13v2.01121,096,728 - 121,106,544 (+)NCBI
Sequence:
RefSeq Acc Id: NR_164758
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381121,087,345 - 121,097,161 (+)NCBI
T2T-CHM13v2.01121,096,728 - 121,106,544 (+)NCBI
Sequence:
RefSeq Acc Id: NR_164759
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381121,087,345 - 121,097,161 (+)NCBI
T2T-CHM13v2.01121,096,728 - 121,106,544 (+)NCBI
Sequence:
RefSeq Acc Id: NR_164760
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381121,087,345 - 121,095,642 (+)NCBI
T2T-CHM13v2.01121,096,728 - 121,105,025 (+)NCBI
Sequence:
Ensembl Acc Id: ENSP00000485498   ⟸   ENST00000623603
Ensembl Acc Id: ENSP00000478655   ⟸   ENST00000616817
Ensembl Acc Id: ENSP00000479641   ⟸   ENST00000472543
Ensembl Acc Id: ENSP00000358390   ⟸   ENST00000369383
Ensembl Acc Id: ENSP00000358391   ⟸   ENST00000369384
Ensembl Acc Id: ENSP00000481411   ⟸   ENST00000369178
Protein Domains
Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q92637-F1-model_v2 AlphaFold Q92637 1-280 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3614 AgrOrtholog
COSMIC FCGR1BP COSMIC
Ensembl Genes ENSG00000198019 Ensembl
  ENSG00000291135 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000369383 ENTREZGENE
  ENST00000369384 ENTREZGENE
  ENST00000471609 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000198019 GTEx
  ENSG00000291135 GTEx
HGNC ID HGNC:3614 ENTREZGENE
Human Proteome Map FCGR1BP Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_Fc_receptor UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
NCBI Gene 2210 ENTREZGENE
OMIM 601502 OMIM
PANTHER HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED UniProtKB/Swiss-Prot
  IMMUNOGLOBULIN FC RECEPTOR UniProtKB/Swiss-Prot
Pfam Ig_2 UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt FCGRB_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q7KZ13 UniProtKB/Swiss-Prot
  Q92638 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-11-08 FCGR1BP  Fc gamma receptor Ib, pseudogene  FCGR1B  Fc fragment of IgG receptor Ib  Symbol and/or name change 19259463 PROVISIONAL
2016-01-19 FCGR1B  Fc fragment of IgG receptor Ib  FCGR1B  Fc fragment of IgG, high affinity Ib, receptor (CD64)  Symbol and/or name change 5135510 APPROVED