DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) - Rat Genome Database

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Gene: DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) Homo sapiens
Analyze
Symbol: DNAJB12
Name: DnaJ heat shock protein family (Hsp40) member B12
RGD ID: 1348292
HGNC Page HGNC:14891
Description: Enables Hsp70 protein binding activity. Involved in several processes, including ERAD pathway; cellular response to misfolded protein; and chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum membrane and nuclear membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DJ10; DKFZp586B2023; DnaJ (Hsp40) homolog, subfamily B, member 12; dnaJ homolog subfamily B member 12
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: DNAJB12P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381072,332,863 - 72,354,919 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1072,332,830 - 72,355,149 (-)EnsemblGRCh38hg38GRCh38
GRCh371074,092,621 - 74,114,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361073,762,594 - 73,784,875 (-)NCBINCBI36Build 36hg18NCBI36
Build 341073,762,593 - 73,784,875NCBI
Celera1067,379,461 - 67,399,258 (-)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1068,086,789 - 68,109,106 (-)NCBIHuRef
CHM1_11074,374,374 - 74,396,719 (-)NCBICHM1_1
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:11147971   PMID:12477932   PMID:14702039   PMID:15489334   PMID:17207965   PMID:17342744   PMID:18029348   PMID:19946888   PMID:21148293   PMID:21150129   PMID:21150319  
PMID:21873635   PMID:22939629   PMID:23956138   PMID:24292625   PMID:24732912   PMID:24778252   PMID:25036637   PMID:25959826   PMID:26344197   PMID:26618866   PMID:26972000   PMID:27432908  
PMID:27503909   PMID:27684187   PMID:27916661   PMID:28515276   PMID:28536268   PMID:28611215   PMID:28846114   PMID:29180619   PMID:29509190   PMID:29560723   PMID:29615496   PMID:30166453  
PMID:30833792   PMID:31073040   PMID:31091453   PMID:31527615   PMID:31540324   PMID:31586073   PMID:32344865   PMID:32416067   PMID:32423001   PMID:32457219   PMID:32513696   PMID:32614325  
PMID:32707033   PMID:32788342   PMID:32877691   PMID:33144569   PMID:33239621   PMID:33306668   PMID:33545068   PMID:33671632   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34272738  
PMID:34591612   PMID:34597346   PMID:34672954   PMID:34709727   PMID:35241646   PMID:35253629   PMID:35256949   PMID:35271311   PMID:35384245   PMID:35563538   PMID:35676246   PMID:35696571  
PMID:35777956   PMID:35944360   PMID:35961308   PMID:35993436   PMID:36114006   PMID:36180527   PMID:36215168   PMID:36538041   PMID:36604567   PMID:36610398   PMID:37314216   PMID:37317656  
PMID:37478010   PMID:37827155   PMID:37925033   PMID:37929963   PMID:38569033   PMID:38878854   PMID:39231216  


Genomics

Comparative Map Data
DNAJB12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381072,332,863 - 72,354,919 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1072,332,830 - 72,355,149 (-)EnsemblGRCh38hg38GRCh38
GRCh371074,092,621 - 74,114,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361073,762,594 - 73,784,875 (-)NCBINCBI36Build 36hg18NCBI36
Build 341073,762,593 - 73,784,875NCBI
Celera1067,379,461 - 67,399,258 (-)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1068,086,789 - 68,109,106 (-)NCBIHuRef
CHM1_11074,374,374 - 74,396,719 (-)NCBICHM1_1
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBIT2T-CHM13v2.0
Dnajb12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391059,715,405 - 59,735,118 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1059,715,378 - 59,735,124 (+)EnsemblGRCm39 Ensembl
GRCm381059,879,583 - 59,899,296 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1059,879,556 - 59,899,302 (+)EnsemblGRCm38mm10GRCm38
MGSCv371059,342,339 - 59,360,764 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361059,274,948 - 59,293,373 (+)NCBIMGSCv36mm8
Celera1060,977,044 - 60,995,371 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.64NCBI
Dnajb12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82028,371,180 - 28,389,390 (+)NCBIGRCr8
mRatBN7.22027,828,216 - 27,846,428 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2027,828,235 - 27,846,427 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2028,839,821 - 28,858,023 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02028,226,094 - 28,244,296 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02028,968,945 - 28,987,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02029,445,510 - 29,463,739 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,445,510 - 29,463,738 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,249,072 - 31,266,938 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,188,065 - 27,206,148 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12027,201,864 - 27,219,947 (+)NCBI
Celera2029,269,844 - 29,288,037 (+)NCBICelera
Cytogenetic Map20q11NCBI
Dnajb12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543719,266,206 - 19,288,854 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543719,266,206 - 19,285,654 (+)NCBIChiLan1.0ChiLan1.0
DNAJB12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2884,480,641 - 84,503,970 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11084,485,962 - 84,508,244 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01068,852,913 - 68,875,307 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11071,319,836 - 71,341,876 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1071,319,836 - 71,341,789 (-)Ensemblpanpan1.1panPan2
DNAJB12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1422,964,098 - 22,980,291 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl422,965,967 - 22,980,292 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha423,102,398 - 23,118,625 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0423,243,979 - 23,261,880 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl423,245,766 - 23,261,871 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1423,145,129 - 23,163,017 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0423,345,955 - 23,363,911 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0423,699,654 - 23,717,628 (-)NCBIUU_Cfam_GSD_1.0
Dnajb12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721358,091,183 - 58,113,019 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365216,583,908 - 6,607,628 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365216,583,828 - 6,605,744 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJB12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1475,169,077 - 75,189,883 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11475,169,076 - 75,190,109 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21481,218,690 - 81,239,723 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJB12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1958,954,908 - 58,976,453 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl958,955,201 - 58,976,943 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604819,568,334 - 19,592,009 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajb12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247546,131,271 - 6,149,522 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247546,131,180 - 6,149,597 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DNAJB12
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q21.2-22.2(chr10:62229688-74468143)x1 copy number loss See cases [RCV000052530] Chr10:62229688..74468143 [GRCh38]
Chr10:63989447..76227901 [GRCh37]
Chr10:63659453..75897907 [NCBI36]
Chr10:10q21.2-22.2		 pathogenic
GRCh38/hg38 10q21.1-22.2(chr10:58436466-74415216)x1 copy number loss See cases [RCV000052511] Chr10:58436466..74415216 [GRCh38]
Chr10:60196226..76174974 [GRCh37]
Chr10:59866232..75844980 [NCBI36]
Chr10:10q21.1-22.2		 pathogenic
GRCh38/hg38 10q11.21-22.2(chr10:42685306-73715908)x3 copy number gain See cases [RCV000134848] Chr10:42685306..73715908 [GRCh38]
Chr10:43180754..75475666 [GRCh37]
Chr10:42500760..75145672 [NCBI36]
Chr10:10q11.21-22.2		 pathogenic
GRCh38/hg38 10q21.3-22.3(chr10:67196567-79422057)x3 copy number gain See cases [RCV000135438] Chr10:67196567..79422057 [GRCh38]
Chr10:68956325..81181813 [GRCh37]
Chr10:68626331..80851819 [NCBI36]
Chr10:10q21.3-22.3		 pathogenic
GRCh38/hg38 10q21.3-22.2(chr10:63402579-75296099)x1 copy number loss See cases [RCV000136658] Chr10:63402579..75296099 [GRCh38]
Chr10:65162339..77055857 [GRCh37]
Chr10:64832345..76725863 [NCBI36]
Chr10:10q21.3-22.2		 pathogenic|likely benign
GRCh38/hg38 10q11.23-23.2(chr10:50729367-87147204)x3 copy number gain See cases [RCV000138007] Chr10:50729367..87147204 [GRCh38]
Chr10:52489127..88906961 [GRCh37]
Chr10:52159133..88896941 [NCBI36]
Chr10:10q11.23-23.2		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
GRCh37/hg19 10q21.3-23.32(chr10:69040366-93194993)x3 copy number gain not provided [RCV000683289] Chr10:69040366..93194993 [GRCh37]
Chr10:10q21.3-23.32		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
NM_017626.7(DNAJB12):c.703C>T (p.Arg235Cys) single nucleotide variant not specified [RCV004308338] Chr10:72340809 [GRCh38]
Chr10:74100567 [GRCh37]
Chr10:10q22.1		 uncertain significance
GRCh37/hg19 10q21.3-22.3(chr10:68735254-78885714) copy number loss not specified [RCV002052875] Chr10:68735254..78885714 [GRCh37]
Chr10:10q21.3-22.3		 pathogenic
NM_017626.7(DNAJB12):c.27G>T (p.Glu9Asp) single nucleotide variant not specified [RCV004109566] Chr10:72354871 [GRCh38]
Chr10:74114629 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.74A>G (p.Asp25Gly) single nucleotide variant not specified [RCV004209297] Chr10:72354824 [GRCh38]
Chr10:74114582 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.638C>G (p.Pro213Arg) single nucleotide variant not specified [RCV004145562] Chr10:72340990 [GRCh38]
Chr10:74100748 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.520G>A (p.Gly174Ser) single nucleotide variant not specified [RCV004221103] Chr10:72341108 [GRCh38]
Chr10:74100866 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.188C>T (p.Pro63Leu) single nucleotide variant not specified [RCV004182921] Chr10:72345073 [GRCh38]
Chr10:74104831 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.947A>C (p.Asn316Thr) single nucleotide variant not specified [RCV004169345] Chr10:72336583 [GRCh38]
Chr10:74096341 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.-2C>T single nucleotide variant not specified [RCV004151126] Chr10:72354899 [GRCh38]
Chr10:74114657 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.702C>G (p.Asp234Glu) single nucleotide variant not specified [RCV004174622] Chr10:72340810 [GRCh38]
Chr10:74100568 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.880G>A (p.Val294Ile) single nucleotide variant not specified [RCV004196616] Chr10:72336650 [GRCh38]
Chr10:74096408 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.874G>A (p.Gly292Ser) single nucleotide variant not specified [RCV004278334] Chr10:72336656 [GRCh38]
Chr10:74096414 [GRCh37]
Chr10:10q22.1		 likely benign
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
NM_017626.7(DNAJB12):c.662G>A (p.Ser221Asn) single nucleotide variant not specified [RCV004302758] Chr10:72340850 [GRCh38]
Chr10:74100608 [GRCh37]
Chr10:10q22.1		 uncertain significance
GRCh37/hg19 10q22.1(chr10:73321269-74612651)x1 copy number loss not provided [RCV003483098] Chr10:73321269..74612651 [GRCh37]
Chr10:10q22.1		 uncertain significance
GRCh37/hg19 10q11.21-24.2(chr10:42709645-100834951)x3 copy number gain not provided [RCV003484798] Chr10:42709645..100834951 [GRCh37]
Chr10:10q11.21-24.2		 pathogenic
NM_001002762.2(DNAJB12):c.46G>C (p.Ala16Pro) single nucleotide variant not specified [RCV004379268] Chr10:72354954 [GRCh38]
Chr10:74114712 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.808C>G (p.Pro270Ala) single nucleotide variant not specified [RCV004379269] Chr10:72338227 [GRCh38]
Chr10:74097985 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.242C>T (p.Ser81Leu) single nucleotide variant not specified [RCV004379267] Chr10:72345019 [GRCh38]
Chr10:74104777 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.838G>A (p.Val280Met) single nucleotide variant not specified [RCV004379270] Chr10:72336692 [GRCh38]
Chr10:74096450 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.940G>A (p.Glu314Lys) single nucleotide variant not specified [RCV004622142] Chr10:72336590 [GRCh38]
Chr10:74096348 [GRCh37]
Chr10:10q22.1		 uncertain significance
NM_017626.7(DNAJB12):c.967G>A (p.Ala323Thr) single nucleotide variant not specified [RCV004622141] Chr10:72336563 [GRCh38]
Chr10:74096321 [GRCh37]
Chr10:10q22.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5247
Count of miRNA genes:985
Interacting mature miRNAs:1216
Transcripts:ENST00000338820, ENST00000394903, ENST00000444643, ENST00000461919, ENST00000463786, ENST00000473051
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597108769GWAS1204843_Hself reported educational attainment QTL GWAS1204843 (human)6e-11self reported educational attainment107234088472340885Human
597357586GWAS1453660_Hbody height QTL GWAS1453660 (human)3e-09body height (VT:0001253)body height (CMO:0000106)107234970172349702Human
597060221GWAS1156295_Hrefractive error, age at onset, Myopia QTL GWAS1156295 (human)2e-08refractive error, age at onset, Myopia107234052172340522Human
597214263GWAS1310337_Hmathematical ability QTL GWAS1310337 (human)1e-08mathematical ability107234088472340885Human

Markers in Region
RH99109  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37265,727,918 - 65,728,056UniSTSGRCh37
GRCh371074,095,638 - 74,096,368UniSTSGRCh37
Build 36265,581,422 - 65,581,560RGDNCBI36
Celera1067,379,988 - 67,380,718UniSTS
Celera265,574,605 - 65,574,743RGD
Cytogenetic Map2p14UniSTS
Cytogenetic Map10q22.1UniSTS
HuRef265,462,788 - 65,462,926UniSTS
HuRef1068,089,837 - 68,090,567UniSTS
GeneMap99-GB4 RH Map10374.68UniSTS
DNAJB12_8056  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371074,093,955 - 74,094,772UniSTSGRCh37
Build 361073,763,961 - 73,764,778RGDNCBI36
HuRef1068,088,154 - 68,088,971UniSTS
RH44259  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371074,092,720 - 74,092,849UniSTSGRCh37
Build 361073,762,726 - 73,762,855RGDNCBI36
Cytogenetic Map10q22.1UniSTS
HuRef1068,086,921 - 68,087,050UniSTS
GeneMap99-GB4 RH Map10374.58UniSTS
NCBI RH Map10905.6UniSTS
A002G40  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371074,092,783 - 74,092,930UniSTSGRCh37
Build 361073,762,789 - 73,762,936RGDNCBI36
Cytogenetic Map10q22.1UniSTS
HuRef1068,086,984 - 68,087,131UniSTS
GeneMap99-GB4 RH Map10374.68UniSTS
Whitehead-RH Map10450.2UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001002762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_157570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK000034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK123129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK302071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI520000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ935010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC397260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000338820   ⟹   ENSP00000345575
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,332,830 - 72,355,149 (-)Ensembl
Ensembl Acc Id: ENST00000394903   ⟹   ENSP00000378363
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,332,830 - 72,355,149 (-)Ensembl
Ensembl Acc Id: ENST00000444643   ⟹   ENSP00000403313
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,332,863 - 72,354,919 (-)Ensembl
Ensembl Acc Id: ENST00000461919   ⟹   ENSP00000476453
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,334,081 - 72,354,380 (-)Ensembl
Ensembl Acc Id: ENST00000463786   ⟹   ENSP00000476941
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,334,523 - 72,344,961 (-)Ensembl
Ensembl Acc Id: ENST00000473051
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1072,335,557 - 72,336,865 (-)Ensembl
RefSeq Acc Id: NM_001002762   ⟹   NP_001002762
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,332,863 - 72,354,919 (-)NCBI
GRCh371074,092,588 - 74,114,907 (-)RGD
Build 361073,762,594 - 73,784,875 (-)NCBI Archive
Celera1067,379,461 - 67,399,258 (-)RGD
HuRef1068,086,789 - 68,109,106 (-)ENTREZGENE
CHM1_11074,374,374 - 74,396,719 (-)NCBI
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365080   ⟹   NP_001352009
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,332,863 - 72,354,919 (-)NCBI
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365081   ⟹   NP_001352010
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,332,863 - 72,354,919 (-)NCBI
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBI
Sequence:
RefSeq Acc Id: NM_017626   ⟹   NP_060096
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,332,863 - 72,354,919 (-)NCBI
GRCh371074,092,588 - 74,114,907 (-)RGD
Build 361073,762,594 - 73,784,875 (-)NCBI Archive
Celera1067,379,461 - 67,399,258 (-)RGD
HuRef1068,086,789 - 68,109,106 (-)ENTREZGENE
CHM1_11074,374,374 - 74,396,719 (-)NCBI
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBI
Sequence:
RefSeq Acc Id: NR_157570
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,332,863 - 72,354,919 (-)NCBI
T2T-CHM13v2.01073,203,895 - 73,225,949 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001002762   ⟸   NM_001002762
- Peptide Label: isoform 1
- UniProtKB: Q9NXW2 (UniProtKB/Swiss-Prot),   B7Z7I3 (UniProtKB/Swiss-Prot),   Q9H6H0 (UniProtKB/Swiss-Prot),   J3KPS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_060096   ⟸   NM_017626
- Peptide Label: isoform 1
- UniProtKB: Q9NXW2 (UniProtKB/Swiss-Prot),   B7Z7I3 (UniProtKB/Swiss-Prot),   Q9H6H0 (UniProtKB/Swiss-Prot),   J3KPS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001352009   ⟸   NM_001365080
- Peptide Label: isoform 2
- UniProtKB: J3KPS0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001352010   ⟸   NM_001365081
- Peptide Label: isoform 1
- UniProtKB: Q9NXW2 (UniProtKB/Swiss-Prot),   B7Z7I3 (UniProtKB/Swiss-Prot),   Q9H6H0 (UniProtKB/Swiss-Prot),   J3KPS0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000476941   ⟸   ENST00000463786
Ensembl Acc Id: ENSP00000345575   ⟸   ENST00000338820
Ensembl Acc Id: ENSP00000403313   ⟸   ENST00000444643
Ensembl Acc Id: ENSP00000378363   ⟸   ENST00000394903
Ensembl Acc Id: ENSP00000476453   ⟸   ENST00000461919
Protein Domains
DUF1977   J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NXW2-F1-model_v2 AlphaFold Q9NXW2 1-375 view protein structure

Promoters
RGD ID:7217813
Promoter ID:EPDNEW_H14652
Type:initiation region
Name:DNAJB12_2
Description:DnaJ heat shock protein family member B12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14653  EPDNEW_H14654  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,336,856 - 72,336,916EPDNEW
RGD ID:7217815
Promoter ID:EPDNEW_H14653
Type:initiation region
Name:DNAJB12_1
Description:DnaJ heat shock protein family member B12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14652  EPDNEW_H14654  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,354,919 - 72,354,979EPDNEW
RGD ID:7217817
Promoter ID:EPDNEW_H14654
Type:initiation region
Name:DNAJB12_3
Description:DnaJ heat shock protein family member B12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H14652  EPDNEW_H14653  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381072,355,129 - 72,355,189EPDNEW
RGD ID:6787507
Promoter ID:HG_KWN:9986
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000048584
Position:
Human AssemblyChrPosition (strand)Source
Build 361073,766,351 - 73,767,147 (-)MPROMDB
RGD ID:6787505
Promoter ID:HG_KWN:9987
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000048582
Position:
Human AssemblyChrPosition (strand)Source
Build 361073,773,006 - 73,773,506 (-)MPROMDB
RGD ID:6787513
Promoter ID:HG_KWN:9988
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001002762,   OTTHUMT00000048581,   UC001JSY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361073,784,376 - 73,784,876 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14891 AgrOrtholog
COSMIC DNAJB12 COSMIC
Ensembl Genes ENSG00000148719 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000338820 ENTREZGENE
  ENST00000338820.7 UniProtKB/TrEMBL
  ENST00000394903.6 UniProtKB/TrEMBL
  ENST00000444643 ENTREZGENE
  ENST00000444643.8 UniProtKB/Swiss-Prot
  ENST00000461919.5 UniProtKB/TrEMBL
  ENST00000463786.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000148719 GTEx
HGNC ID HGNC:14891 ENTREZGENE
Human Proteome Map DNAJB12 Human Proteome Map
InterPro DnaJ_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DnaJ_domain_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DnaJ_subfamily_B/C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1977_DnaJ-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  J_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:54788 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 54788 ENTREZGENE
OMIM 608376 OMIM
PANTHER AT29763P-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAJ HOMOLOG SUBFAMILY B MEMBER 12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1977 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA27414 PharmGKB
PRINTS JDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNAJ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAJ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B7Z7I3 ENTREZGENE
  DJB12_HUMAN UniProtKB/Swiss-Prot
  J3KPS0 ENTREZGENE, UniProtKB/TrEMBL
  Q9H6H0 ENTREZGENE
  Q9NXW2 ENTREZGENE
  V9GY70_HUMAN UniProtKB/TrEMBL
  V9GYN7_HUMAN UniProtKB/TrEMBL
UniProt Secondary B7Z7I3 UniProtKB/Swiss-Prot
  Q9H6H0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 DNAJB12  DnaJ heat shock protein family (Hsp40) member B12  DNAJB12  DnaJ (Hsp40) homolog, subfamily B, member 12  Symbol and/or name change 5135510 APPROVED