Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | LIMD1 | Human | (+)-schisandrin B | multiple interactions | ISO | Limd1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of LIMD1 mRNA] | CTD | PMID:31150632 | LIMD1 | Human | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LIMD1 mRNA | CTD | PMID:22079256 | LIMD1 | Human | 1,2-dimethylhydrazine | multiple interactions | ISO | Limd1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LIMD1 mRNA | CTD | PMID:22206623 | LIMD1 | Human | 2,3',4,4',5-Pentachlorobiphenyl | decreases expression | ISO | Limd1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | LIMD1 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LIMD1 mRNA | CTD | PMID:22298810 | LIMD1 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Limd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LIMD1 mRNA | CTD | PMID:21570461 | LIMD1 | Human | 2,4-dinitrotoluene | affects expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of LIMD1 mRNA | CTD | PMID:21346803 | LIMD1 | Human | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of LIMD1 mRNA | CTD | PMID:37199045 | LIMD1 | Human | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of LIMD1 gene | CTD | PMID:31601247 | LIMD1 | Human | 4,4'-sulfonyldiphenol | affects methylation | ISO | Limd1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of LIMD1 gene | CTD | PMID:31683443 | LIMD1 | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of LIMD1 mRNA | CTD | PMID:24780913 | LIMD1 | Human | 7,12-dimethyltetraphene | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | 9 more ... | CTD | PMID:19480007 | LIMD1 | Human | amphetamine | decreases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of LIMD1 mRNA | CTD | PMID:30779732 | LIMD1 | Human | arsane | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of LIMD1 gene | CTD | PMID:25304211 | LIMD1 | Human | arsenic atom | affects methylation | EXP | | 6480464 | Arsenic affects the methylation of LIMD1 gene | CTD | PMID:25304211 | LIMD1 | Human | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LIMD1 mRNA] | CTD | PMID:32406909 | LIMD1 | Human | arsenous acid | multiple interactions | EXP | | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LIMD1 protein] | CTD | PMID:26598702 | LIMD1 | Human | atrazine | affects methylation | ISO | Limd1 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of LIMD1 gene | CTD | PMID:35440735 | LIMD1 | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of LIMD1 exon and Benzo(a)pyrene results in increased methylation of LIMD1 promoter | CTD | PMID:27901495 | LIMD1 | Human | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of LIMD1 3' UTR | CTD | PMID:27901495 | LIMD1 | Human | bisphenol A | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of LIMD1 mRNA | CTD | PMID:25181051 and PMID:27178563 | LIMD1 | Human | bisphenol A | decreases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of LIMD1 mRNA | CTD | PMID:34947998 | LIMD1 | Human | bisphenol A | increases expression | ISO | Limd1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LIMD1 mRNA | CTD | PMID:33221593 | LIMD1 | Human | bortezomib | increases expression | EXP | | 6480464 | Bortezomib results in increased expression of LIMD1 mRNA | CTD | PMID:20977926 | LIMD1 | Human | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of LIMD1 mRNA | CTD | PMID:26079696 | LIMD1 | Human | cadmium dichloride | decreases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of LIMD1 mRNA | CTD | PMID:33453195 | LIMD1 | Human | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of LIMD1 protein | CTD | PMID:35688186 | LIMD1 | Human | coumarin | increases phosphorylation | EXP | | 6480464 | coumarin results in increased phosphorylation of LIMD1 protein | CTD | PMID:35688186 | LIMD1 | Human | cyclophosphamide | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Cyclophosphamide results in increased expression of LIMD1 mRNA | CTD | PMID:27281708 | LIMD1 | Human | dexamethasone | increases expression | ISO | Limd1 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of LIMD1 mRNA | CTD | PMID:22733784 | LIMD1 | Human | diarsenic trioxide | multiple interactions | EXP | | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to LIMD1 protein] | CTD | PMID:26598702 | LIMD1 | Human | dicrotophos | increases expression | EXP | | 6480464 | dicrotophos results in increased expression of LIMD1 mRNA | CTD | PMID:28302478 | LIMD1 | Human | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of LIMD1 protein | CTD | PMID:23301498 | LIMD1 | Human | ethanol | increases expression | ISO | Limd1 (Mus musculus) | 6480464 | Ethanol results in increased expression of LIMD1 mRNA | CTD | PMID:30319688 | LIMD1 | Human | fenvalerate | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of LIMD1 mRNA | CTD | PMID:30307764 | LIMD1 | Human | folic acid | multiple interactions | ISO | Limd1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LIMD1 mRNA | CTD | PMID:22206623 | LIMD1 | Human | gentamycin | decreases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of LIMD1 mRNA | CTD | PMID:33387578 | LIMD1 | Human | isoprenaline | increases expression | ISO | Limd1 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of LIMD1 mRNA | CTD | PMID:20003209 | LIMD1 | Human | ivermectin | increases expression | EXP | | 6480464 | Ivermectin results in increased expression of LIMD1 protein | CTD | PMID:32959892 | LIMD1 | Human | levonorgestrel | multiple interactions | EXP | | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LIMD1 mRNA | CTD | PMID:19074003 | LIMD1 | Human | mercury atom | decreases expression | ISO | Limd1 (Mus musculus) | 6480464 | Mercury analog results in decreased expression of LIMD1 mRNA | CTD | PMID:25056781 | LIMD1 | Human | mercury(0) | decreases expression | ISO | Limd1 (Mus musculus) | 6480464 | Mercury analog results in decreased expression of LIMD1 mRNA | CTD | PMID:25056781 | LIMD1 | Human | methotrexate | decreases expression | EXP | | 6480464 | Methotrexate results in decreased expression of LIMD1 mRNA | CTD | PMID:24449571 | LIMD1 | Human | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of LIMD1 mRNA | CTD | PMID:21420995 | LIMD1 | Human | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of LIMD1 mRNA | CTD | PMID:22079256 | LIMD1 | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of LIMD1 mRNA | CTD | PMID:22079256 | LIMD1 | Human | sodium arsenite | multiple interactions | EXP | | 6480464 | sodium arsenite results in increased expression of and affects the splicing of LIMD1 mRNA | CTD | PMID:25879800 | LIMD1 | Human | Soman | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Soman results in increased expression of LIMD1 mRNA | CTD | PMID:19281266 | LIMD1 | Human | testosterone undecanoate | multiple interactions | EXP | | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LIMD1 mRNA | CTD | PMID:19074003 | LIMD1 | Human | tetrachloromethane | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of LIMD1 mRNA | CTD | PMID:31150632 | LIMD1 | Human | tetrachloromethane | multiple interactions | ISO | Limd1 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of LIMD1 mRNA] | CTD | PMID:31150632 | LIMD1 | Human | thioacetamide | increases expression | ISO | Limd1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of LIMD1 mRNA | CTD | PMID:34492290 | LIMD1 | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of LIMD1 mRNA | CTD | PMID:37042841 | LIMD1 | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of LIMD1 mRNA | CTD | PMID:23179753 | LIMD1 | Human | valproic acid | decreases methylation | EXP | | 6480464 | Valproic Acid results in decreased methylation of LIMD1 gene | CTD | PMID:29154799 | LIMD1 | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of LIMD1 mRNA | CTD | PMID:25979313 | |