Tagap1 (T cell activation GTPase activating protein 1) - Rat Genome Database

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Gene: Tagap1 (T cell activation GTPase activating protein 1) Mus musculus
Analyze
No known orthologs.
Symbol: Tagap1
Name: T cell activation GTPase activating protein 1
RGD ID: 1318497
MGI Page MGI
Description: Orthologous to human TAGAP (T cell activation RhoGTPase activating protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610315E15Rik; AA415005; FKSG15; T-cell activation GTPase activating protein 1; T-cell activation GTPase-activating protein 1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39177,222,364 - 7,246,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl177,222,410 - 7,228,555 (-)EnsemblGRCm39 Ensembl
GRCm38176,954,965 - 6,961,565 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,955,011 - 6,961,156 (-)EnsemblGRCm38mm10GRCm38
MGSCv37177,159,314 - 7,165,505 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36176,805,155 - 6,810,814 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map174.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466305   PMID:12466851   PMID:12477932   PMID:16116428   PMID:16141072   PMID:16141073   PMID:18363199  
PMID:19468303   PMID:21873635   PMID:38355793  


Genomics

Variants

.
Variants in Tagap1
676 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:271
Count of miRNA genes:231
Interacting mature miRNAs:245
Transcripts:ENSMUST00000063683
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse

Markers in Region
RH124372  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38177,933,376 - 7,933,606UniSTSGRCm38
GRCm38176,956,301 - 6,956,531UniSTSGRCm38
MGSCv37178,126,241 - 8,126,471UniSTSGRCm37
MGSCv371740,968 - 41,198UniSTSGRCm37
MGSCv37177,160,650 - 7,160,880UniSTSGRCm37
Celera177,486,866 - 7,487,096UniSTS
Cytogenetic Map17A1UniSTS
UniSTS:237565  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38177,934,475 - 7,934,608UniSTSGRCm38
GRCm38176,955,300 - 6,955,433UniSTSGRCm38
MGSCv37178,127,340 - 8,127,473UniSTSGRCm37
MGSCv371739,966 - 40,099UniSTSGRCm37
MGSCv37177,159,649 - 7,159,782UniSTSGRCm37
Celera177,485,864 - 7,485,997UniSTS
Cytogenetic Map17A1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000063683   ⟹   ENSMUSP00000070466
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl177,222,410 - 7,228,555 (-)Ensembl
GRCm38.p6 Ensembl176,955,011 - 6,961,156 (-)Ensembl
RefSeq Acc Id: NM_147155   ⟹   NP_671511
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39177,222,364 - 7,228,555 (-)NCBI
GRCm38176,954,965 - 6,961,156 (-)NCBI
MGSCv37177,159,314 - 7,165,505 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011246178   ⟹   XP_011244480
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39177,222,404 - 7,228,961 (-)NCBI
GRCm38176,955,005 - 6,961,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160658   ⟹   XP_036016551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39177,222,404 - 7,246,122 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_671511 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244480 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016551 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL16686 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000070466
  ENSMUSP00000070466.7
GenBank Protein P0CAX8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_671511   ⟸   NM_147155
- UniProtKB: P0CAX8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011244480   ⟸   XM_011246178
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000070466   ⟸   ENSMUST00000063683
RefSeq Acc Id: XP_036016551   ⟸   XM_036160658
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0CAX8-F1-model_v2 AlphaFold P0CAX8 1-505 view protein structure

Promoters
RGD ID:13674676
Promoter ID:EPDNEW_M21487
Type:multiple initiation site
Name:Tagap1_1
Description:Mus musculus T cell activation GTPase activating protein 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38176,961,145 - 6,961,205EPDNEW
RGD ID:6828743
Promoter ID:MM_KWN:22026
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell
Transcripts:NM_147155
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36177,165,466 - 7,166,132 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919786 AgrOrtholog
Ensembl Genes ENSMUSG00000052031 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000063683 ENTREZGENE
  ENSMUST00000063683.8 UniProtKB/Swiss-Prot
KEGG Report mmu:380608 UniProtKB/Swiss-Prot
MGD MGI:1919786 ENTREZGENE
NCBI Gene 380608 ENTREZGENE
PANTHER T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED UniProtKB/Swiss-Prot
  T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot
PhenoGen Tagap1 PhenoGen
UniProt P0CAX8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8K2L9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-02-07 Tagap1  T cell activation GTPase activating protein 1  Tagap1  T-cell activation GTPase activating protein 1  Symbol and/or name change 5135510 APPROVED