Cdr2l (cerebellar degeneration-related protein 2-like) - Rat Genome Database

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Gene: Cdr2l (cerebellar degeneration-related protein 2-like) Mus musculus
Analyze
Symbol: Cdr2l
Name: cerebellar degeneration-related protein 2-like
RGD ID: 1315750
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Orthologous to human CDR2L (cerebellar degeneration related protein 2 like).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D030068L24Rik; Gm21
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,272,700 - 115,286,961 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,272,742 - 115,286,958 (+)EnsemblGRCm39 Ensembl
GRCm3811115,381,871 - 115,396,135 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,381,916 - 115,396,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,243,230 - 115,257,446 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,198,431 - 115,212,220 (+)NCBIMGSCv36mm8
Celera11127,147,762 - 127,162,094 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15782199   PMID:16141072   PMID:16141073   PMID:21267068  


Genomics

Comparative Map Data
Cdr2l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,272,700 - 115,286,961 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,272,742 - 115,286,958 (+)EnsemblGRCm39 Ensembl
GRCm3811115,381,871 - 115,396,135 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,381,916 - 115,396,132 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,243,230 - 115,257,446 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,198,431 - 115,212,220 (+)NCBIMGSCv36mm8
Celera11127,147,762 - 127,162,094 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.84NCBI
CDR2L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381774,987,632 - 75,005,800 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1774,987,632 - 75,005,800 (+)EnsemblGRCh38hg38GRCh38
GRCh371772,983,727 - 73,001,895 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,495,322 - 70,513,490 (+)NCBINCBI36Build 36hg18NCBI36
Celera1769,576,957 - 69,595,142 (+)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1768,394,072 - 68,412,255 (+)NCBIHuRef
CHM1_11773,048,534 - 73,066,701 (+)NCBICHM1_1
T2T-CHM13v2.01775,879,422 - 75,897,596 (+)NCBIT2T-CHM13v2.0
Cdr2l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,123,777 - 101,137,634 (+)NCBIGRCr8
mRatBN7.210100,625,150 - 100,638,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10100,624,607 - 100,638,666 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.010103,934,364 - 103,948,318 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10103,934,797 - 103,948,322 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,330,246 - 104,358,063 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,460,482 - 105,472,167 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110105,462,808 - 105,486,792 (+)NCBI
Celera1099,200,004 - 99,213,864 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Cdr2l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555531,851,810 - 1,866,521 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555531,851,338 - 1,863,772 (+)NCBIChiLan1.0ChiLan1.0
CDR2L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,024,776 - 91,042,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11795,847,723 - 95,867,762 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01768,933,141 - 68,951,297 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11774,488,503 - 74,506,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1774,488,503 - 74,506,589 (+)Ensemblpanpan1.1panPan2
CDR2L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,459,723 - 5,472,478 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl95,459,726 - 5,473,053 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha96,137,843 - 6,150,605 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.096,129,554 - 6,142,823 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl96,129,571 - 6,143,337 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.196,167,166 - 6,179,993 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.096,277,506 - 6,290,315 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.096,337,912 - 6,350,743 (-)NCBIUU_Cfam_GSD_1.0
Cdr2l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056026,082,630 - 6,095,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594316,329 - 329,899 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594316,339 - 329,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDR2L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl126,270,575 - 6,282,422 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1126,270,566 - 6,282,471 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,255,244 - 6,267,134 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDR2L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,672,061 - 46,689,495 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,672,063 - 46,689,458 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607717,458,206 - 17,475,550 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdr2l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248014,817,799 - 4,830,078 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248014,817,765 - 4,830,500 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdr2l
451 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:772
Count of miRNA genes:459
Interacting mature miRNAs:517
Transcripts:ENSMUST00000053288
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000053288   ⟹   ENSMUSP00000052096
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,272,742 - 115,286,958 (+)Ensembl
GRCm38.p6 Ensembl11115,381,916 - 115,396,132 (+)Ensembl
RefSeq Acc Id: NM_001080929   ⟹   NP_001074398
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,272,742 - 115,286,958 (+)NCBI
GRCm3811115,381,916 - 115,396,132 (+)ENTREZGENE
MGSCv3711115,243,230 - 115,257,446 (+)RGD
Celera11127,147,762 - 127,162,094 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011249000   ⟹   XP_011247302
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,272,700 - 115,286,961 (+)NCBI
GRCm3811115,381,871 - 115,396,135 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245980   ⟹   XP_030101840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,272,702 - 115,286,961 (+)NCBI
GRCm3811115,382,324 - 115,396,135 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074398 (Get FASTA)   NCBI Sequence Viewer  
  XP_011247302 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101840 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A2A6T1 (Get FASTA)   NCBI Sequence Viewer  
  AAI44824 (Get FASTA)   NCBI Sequence Viewer  
  AAI50669 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000052096
  ENSMUSP00000052096.6
RefSeq Acc Id: NP_001074398   ⟸   NM_001080929
- UniProtKB: A2A6T1 (UniProtKB/Swiss-Prot),   B2RWR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247302   ⟸   XM_011249000
- Peptide Label: isoform X1
- UniProtKB: B2RWR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101840   ⟸   XM_030245980
- Peptide Label: isoform X1
- UniProtKB: B2RWR4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000052096   ⟸   ENSMUST00000053288

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2A6T1-F1-model_v2 AlphaFold A2A6T1 1-465 view protein structure

Promoters
RGD ID:6820603
Promoter ID:MM_KWN:10520
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001080929
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611115,242,989 - 115,243,489 (+)MPROMDB
RGD ID:8677334
Promoter ID:EPDNEW_M16698
Type:initiation region
Name:Cdr2l_1
Description:Mus musculus cerebellar degeneration-related protein 2-like ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811115,381,914 - 115,381,974EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684867 AgrOrtholog
Ensembl Genes ENSMUSG00000050910 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000053288 ENTREZGENE
  ENSMUST00000053288.6 UniProtKB/Swiss-Prot
InterPro CDR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:237988 UniProtKB/Swiss-Prot
MGD MGI:2684867 ENTREZGENE
NCBI Gene 237988 ENTREZGENE
PANTHER CEREBELLAR DEGENERATION-RELATED PROTEIN 2-LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19232 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdr2l PhenoGen
UniProt A2A6T1 ENTREZGENE
  B2RWR4 ENTREZGENE, UniProtKB/TrEMBL
  B7ZMV4_MOUSE UniProtKB/TrEMBL
  CDR2L_MOUSE UniProtKB/Swiss-Prot