Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Agfg2 | Mouse | (+)-schisandrin B | multiple interactions | ISO | Agfg2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AGFG2 mRNA] | CTD | PMID:31150632 | Agfg2 | Mouse | 1,2-dimethylhydrazine | affects expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of AGFG2 mRNA | CTD | PMID:22206623 | Agfg2 | Mouse | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AGFG2 mRNA | CTD | PMID:17942748 | Agfg2 | Mouse | 17beta-estradiol | multiple interactions | ISO | AGFG2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of AGFG2 mRNA | CTD | PMID:30165855 | Agfg2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AGFG2 mRNA | CTD | PMID:17942748 | Agfg2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AGFG2 mRNA and Tetrachlorodibenzodioxin results in increased expression of CCZ1B mRNA | CTD | PMID:33387578 and PMID:34747641 | Agfg2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of AGFG2 mRNA | CTD | PMID:21215274 | Agfg2 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of AGFG2 mRNA | CTD | PMID:21570461 | Agfg2 | Mouse | 2-hydroxypropanoic acid | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AGFG2 mRNA | CTD | PMID:30851411 | Agfg2 | Mouse | 3-chloropropane-1,2-diol | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of CCZ1B protein | CTD | PMID:34915118 | Agfg2 | Mouse | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of AGFG2 mRNA | CTD | PMID:28973697 | Agfg2 | Mouse | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of AGFG2 mRNA | CTD | PMID:28973697 | Agfg2 | Mouse | acrylamide | affects expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Acrylamide affects the expression of AGFG2 mRNA | CTD | PMID:28959563 | Agfg2 | Mouse | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of AGFG2 mRNA | CTD | PMID:19770486 | Agfg2 | Mouse | aflatoxin B1 | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of AGFG2 mRNA | CTD | PMID:22100608 and PMID:27153756 | Agfg2 | Mouse | aristolochic acid A | increases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of AGFG2 mRNA | CTD | PMID:33212167 | Agfg2 | Mouse | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of AGFG2 mRNA | CTD | PMID:22228805 | Agfg2 | Mouse | benzo[a]pyrene | affects methylation | ISO | AGFG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of AGFG2 intron and Benzo(a)pyrene affects the methylation of AGFG2 promoter | CTD | PMID:27901495 and PMID:30157460 | Agfg2 | Mouse | benzo[a]pyrene | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of AGFG2 mRNA | CTD | PMID:20106945 and PMID:26238291 | Agfg2 | Mouse | benzo[e]pyrene | affects methylation | ISO | AGFG2 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of AGFG2 intron | CTD | PMID:30157460 | Agfg2 | Mouse | bisphenol A | affects expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of AGFG2 mRNA and bisphenol A affects the expression of CCZ1B mRNA | CTD | PMID:25181051 and PMID:30816183 | Agfg2 | Mouse | bisphenol A | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of AGFG2 mRNA | CTD | PMID:34947998 | Agfg2 | Mouse | bisphenol A | affects expression | ISO | AGFG2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of AGFG2 mRNA | CTD | PMID:30903817 | Agfg2 | Mouse | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of AGFG2 mRNA | CTD | PMID:38685157 | Agfg2 | Mouse | butanal | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of AGFG2 mRNA | CTD | PMID:26079696 | Agfg2 | Mouse | cadmium dichloride | multiple interactions | EXP | | 6480464 | MT3 affects the reaction [Cadmium Chloride affects the expression of AGFG2 mRNA] | CTD | PMID:20371981 | Agfg2 | Mouse | caffeine | increases phosphorylation | ISO | AGFG2 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of AGFG2 protein | CTD | PMID:35688186 | Agfg2 | Mouse | cantharidin | increases expression | EXP | | 6480464 | Cantharidin results in increased expression of AGFG2 mRNA | CTD | PMID:36907384 | Agfg2 | Mouse | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of AGFG2 mRNA | CTD | PMID:25554681 and PMID:25620056 | Agfg2 | Mouse | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of AGFG2 mRNA | CTD | PMID:37019170 | Agfg2 | Mouse | cisplatin | increases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of AGFG2 mRNA | CTD | PMID:27594783 | Agfg2 | Mouse | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of AGFG2 mRNA | CTD | PMID:23811191 | Agfg2 | Mouse | copper(II) sulfate | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of AGFG2 mRNA | CTD | PMID:19549813 | Agfg2 | Mouse | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of AGFG2 mRNA | CTD | PMID:29279043 | Agfg2 | Mouse | cyclosporin A | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of AGFG2 mRNA | CTD | PMID:20106945 and PMID:25562108 | Agfg2 | Mouse | DDE | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of AGFG2 mRNA | CTD | PMID:38568856 | Agfg2 | Mouse | dexamethasone | increases expression | EXP | | 6480464 | Dexamethasone results in increased expression of AGFG2 mRNA | CTD | PMID:22733784 | Agfg2 | Mouse | Dibutyl phosphate | affects expression | ISO | AGFG2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of AGFG2 mRNA | CTD | PMID:37042841 | Agfg2 | Mouse | doxorubicin | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of AGFG2 mRNA | CTD | PMID:29803840 | Agfg2 | Mouse | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of AGFG2 mRNA | CTD | PMID:35436446 | Agfg2 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of AGFG2 mRNA | CTD | PMID:30319688 | Agfg2 | Mouse | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of AGFG2 mRNA | CTD | PMID:34813904 | Agfg2 | Mouse | finasteride | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of CCZ1B mRNA | CTD | PMID:24136188 | Agfg2 | Mouse | furan | increases methylation | ISO | Agfg2 (Rattus norvegicus) | 6480464 | furan results in increased methylation of AGFG2 gene | CTD | PMID:22079235 | Agfg2 | Mouse | gentamycin | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of AGFG2 mRNA | CTD | PMID:33387578 | Agfg2 | Mouse | hydrogen peroxide | affects expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of AGFG2 mRNA | CTD | PMID:20044591 | Agfg2 | Mouse | iron dichloride | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of AGFG2 mRNA | CTD | PMID:35984750 | Agfg2 | Mouse | lipopolysaccharide | multiple interactions | ISO | AGFG2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of AGFG2 mRNA | CTD | PMID:35811015 | Agfg2 | Mouse | lipopolysaccharide | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of AGFG2 mRNA | CTD | PMID:35811015 | Agfg2 | Mouse | methapyrilene | affects methylation | ISO | AGFG2 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of AGFG2 intron | CTD | PMID:30157460 | Agfg2 | Mouse | nickel atom | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of AGFG2 mRNA | CTD | PMID:24768652 and PMID:25583101 | Agfg2 | Mouse | paracetamol | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of AGFG2 mRNA | CTD | PMID:21420995 and PMID:26690555 | Agfg2 | Mouse | paracetamol | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of CCZ1B mRNA | CTD | PMID:33387578 | Agfg2 | Mouse | paracetamol | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of AGFG2 mRNA | CTD | PMID:33387578 | Agfg2 | Mouse | paracetamol | increases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of AGFG2 mRNA | CTD | PMID:22230336 | Agfg2 | Mouse | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of AGFG2 mRNA | CTD | PMID:21463325 | Agfg2 | Mouse | pentanal | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | pentanal results in decreased expression of AGFG2 mRNA | CTD | PMID:26079696 | Agfg2 | Mouse | perfluorooctanoic acid | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of AGFG2 protein | CTD | PMID:26879310 | Agfg2 | Mouse | perfluorooctanoic acid | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in increased expression of CCZ1B protein | CTD | PMID:34958885 | Agfg2 | Mouse | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of AGFG2 mRNA | CTD | PMID:23091169 | Agfg2 | Mouse | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of AGFG2 mRNA | CTD | PMID:21278054 | Agfg2 | Mouse | rac-lactic acid | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AGFG2 mRNA | CTD | PMID:30851411 | Agfg2 | Mouse | resveratrol | multiple interactions | ISO | AGFG2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of AGFG2 mRNA | CTD | PMID:23557933 | Agfg2 | Mouse | rotenone | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of AGFG2 mRNA | CTD | PMID:28374803 | Agfg2 | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | AGFG2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of AGFG2 mRNA | CTD | PMID:35811015 | Agfg2 | Mouse | silicon dioxide | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of AGFG2 mRNA | CTD | PMID:25895662 | Agfg2 | Mouse | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of AGFG2 mRNA | CTD | PMID:19073995 | Agfg2 | Mouse | sodium arsenite | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of AGFG2 mRNA | CTD | PMID:38568856 | Agfg2 | Mouse | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of AGFG2 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of AGFG2 mRNA | CTD | PMID:21641980 and PMID:26378955 | Agfg2 | Mouse | sulfadimethoxine | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of AGFG2 mRNA | CTD | PMID:30047161 | Agfg2 | Mouse | sulforaphane | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of AGFG2 mRNA | CTD | PMID:31838189 | Agfg2 | Mouse | sulindac | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Sulindac results in increased expression of CCZ1B mRNA | CTD | PMID:24136188 | Agfg2 | Mouse | sunitinib | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of AGFG2 mRNA | CTD | PMID:31533062 | Agfg2 | Mouse | testosterone | increases expression | EXP | | 6480464 | Testosterone deficiency results in increased expression of AGFG2 mRNA | CTD | PMID:33848595 | Agfg2 | Mouse | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of AGFG2 mRNA | CTD | PMID:17484886 | Agfg2 | Mouse | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of AGFG2 mRNA | CTD | PMID:31919559 | Agfg2 | Mouse | tetrachloromethane | multiple interactions | ISO | Agfg2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AGFG2 mRNA] | CTD | PMID:31150632 | Agfg2 | Mouse | tetrachloromethane | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of AGFG2 mRNA | CTD | PMID:31150632 | Agfg2 | Mouse | thioacetamide | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of AGFG2 mRNA | CTD | PMID:34492290 | Agfg2 | Mouse | thiram | decreases expression | ISO | AGFG2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of AGFG2 mRNA | CTD | PMID:38568856 | Agfg2 | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of AGFG2 mRNA | CTD | PMID:29264374 | Agfg2 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of AGFG2 gene and titanium dioxide results in decreased methylation of AGFG2 promoter | CTD | PMID:35295148 | Agfg2 | Mouse | trichostatin A | affects expression | ISO | AGFG2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of AGFG2 mRNA | CTD | PMID:28542535 | Agfg2 | Mouse | vinclozolin | increases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of AGFG2 mRNA | CTD | PMID:22570695 | Agfg2 | Mouse | vinclozolin | decreases expression | ISO | Agfg2 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of AGFG2 mRNA | CTD | PMID:23034163 | Agfg2 | Mouse | zearalenone | increases expression | EXP | | 6480464 | Zearalenone results in increased expression of AGFG2 protein | CTD | PMID:36252740 | |