Tmem178b (transmembrane protein 178B) - Rat Genome Database

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Gene: Tmem178b (transmembrane protein 178B) Ictidomys tridecemlineatus
Analyze
Symbol: Tmem178b
Name: transmembrane protein 178B
RGD ID: 12713071
Description: ASSOCIATED WITH genetic disease (ortholog); RASopathy (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511813,841,443 - 14,182,165 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365925,037,632 - 5,375,963 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365925,037,638 - 5,380,865 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tmem178b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511813,841,443 - 14,182,165 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365925,037,632 - 5,375,963 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365925,037,638 - 5,380,865 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM178B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387141,074,064 - 141,511,296 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7141,074,064 - 141,480,380 (+)EnsemblGRCh38hg38GRCh38
GRCh377140,773,864 - 141,180,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera7135,495,856 - 135,892,222 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7135,070,061 - 135,476,176 (+)NCBIHuRef
CHM1_17140,708,635 - 141,114,459 (+)NCBICHM1_1
T2T-CHM13v2.07142,388,269 - 142,827,078 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27140,112,364 - 140,517,904 (+)NCBI
Tmem178b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39639,848,164 - 40,232,084 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl639,848,395 - 40,232,084 (+)EnsemblGRCm39 Ensembl
GRCm38639,871,230 - 40,255,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl639,871,461 - 40,255,150 (+)EnsemblGRCm38mm10GRCm38
MGSCv37640,060,252 - 40,198,352 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36640,039,860 - 40,177,960 (+)NCBIMGSCv36mm8
Celera640,097,548 - 40,235,798 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.82NCBI
Tmem178b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8469,626,188 - 70,002,400 (+)NCBIGRCr8
mRatBN7.2468,659,425 - 69,035,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl468,657,343 - 69,035,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx473,587,885 - 73,964,173 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0469,508,998 - 69,885,295 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0467,920,067 - 68,296,772 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0467,669,266 - 68,059,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl468,011,932 - 68,059,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0467,476,252 - 67,864,206 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4467,516,104 - 67,790,853 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera463,663,282 - 64,038,672 (+)NCBICelera
Cytogenetic Map4q23NCBI
Tmem178b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554942,081,953 - 2,442,845 (-)NCBIChiLan1.0ChiLan1.0
TMEM178B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26177,855,197 - 178,261,943 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1729,865,451 - 30,272,198 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07132,997,828 - 133,404,714 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17145,468,670 - 145,875,281 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7145,469,580 - 145,865,699 (+)Ensemblpanpan1.1panPan2
TMEM178B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,698,154 - 8,042,210 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl167,707,656 - 8,042,085 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha168,542,269 - 8,885,924 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0167,618,659 - 7,961,428 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl167,628,188 - 7,961,340 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1167,571,577 - 7,913,457 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0167,414,292 - 7,757,515 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,482,669 - 7,825,184 (-)NCBIUU_Cfam_GSD_1.0
TMEM178B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl188,448,887 - 8,843,542 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1188,440,037 - 8,843,480 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2189,364,613 - 9,365,051 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM178B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121109,821,547 - 110,219,623 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660726,496,390 - 6,905,997 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem178b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476521,104,224 - 21,501,628 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005332437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000020535   ⟹   ENSSTOP00000019115
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365925,037,632 - 5,375,963 (+)Ensembl
RefSeq Acc Id: XM_005332437   ⟹   XP_005332494
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511813,841,443 - 14,182,165 (-)NCBI
SpeTri2.0NW_0049365925,037,638 - 5,380,865 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005332494 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019115.2
GenBank Protein KAG3277354 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005332494   ⟸   XM_005332437
- UniProtKB: I3N419 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000019115   ⟸   ENSSTOT00000020535


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000023428 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020535.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
  T178A/B UniProtKB/TrEMBL
NCBI Gene Tmem178b ENTREZGENE
PANTHER PTHR32005 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 178B UniProtKB/TrEMBL
Pfam Claudin_2 UniProtKB/TrEMBL
UniProt I3N419 ENTREZGENE, UniProtKB/TrEMBL