Rhobtb3 (Rho related BTB domain containing 3) - Rat Genome Database

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Gene: Rhobtb3 (Rho related BTB domain containing 3) Ictidomys tridecemlineatus
Analyze
Symbol: Rhobtb3
Name: Rho related BTB domain containing 3
RGD ID: 12692428
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); GTP binding (inferred); INVOLVED IN male gonad development (ortholog); ASSOCIATED WITH COVID-19 (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Rho related BTB domain containing 3, transcript variant X1; Rho related BTB domain containing 3, transcript variant X2; rho-related BTB domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,374,619 - 169,432,780 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365237,559,335 - 7,617,786 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365237,562,054 - 7,618,380 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rhobtb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,374,619 - 169,432,780 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365237,559,335 - 7,617,786 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365237,562,054 - 7,618,380 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHOBTB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38595,717,624 - 95,796,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl595,713,522 - 95,824,383 (+)EnsemblGRCh38hg38GRCh38
GRCh37595,067,040 - 95,132,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36595,092,606 - 95,157,827 (+)NCBINCBI36Build 36hg18NCBI36
Build 34595,092,798 - 95,156,560NCBI
Celera590,945,592 - 91,010,810 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef590,257,253 - 90,322,380 (+)NCBIHuRef
CHM1_1594,499,513 - 94,564,723 (+)NCBICHM1_1
T2T-CHM13v2.0596,232,572 - 96,297,590 (+)NCBIT2T-CHM13v2.0
Rhobtb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391376,017,656 - 76,092,054 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1376,017,656 - 76,092,044 (-)EnsemblGRCm39 Ensembl
GRCm381375,869,537 - 75,943,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1375,869,537 - 75,943,925 (-)EnsemblGRCm38mm10GRCm38
MGSCv371376,006,985 - 76,081,272 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361376,335,539 - 76,409,826 (-)NCBIMGSCv36mm8
Celera1378,189,914 - 78,265,316 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.95NCBI
Rhobtb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,094,972 - 7,201,507 (-)NCBIGRCr8
mRatBN7.225,363,388 - 5,419,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl25,363,388 - 5,419,041 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx212,470,299 - 12,525,964 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0210,569,530 - 10,625,193 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,205,925 - 5,261,578 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.022,627,655 - 2,683,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl22,627,393 - 2,683,116 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.022,626,102 - 2,681,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.422,911,820 - 2,967,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.122,933,865 - 3,007,464 (-)NCBI
Celera21,833,192 - 1,888,641 (-)NCBICelera
Cytogenetic Map2q11NCBI
Rhobtb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541816,772,363 - 16,839,347 (-)NCBIChiLan1.0ChiLan1.0
RHOBTB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2419,582,719 - 19,648,269 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1517,736,325 - 17,801,657 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0519,552,740 - 19,618,055 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1519,698,304 - 19,763,363 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl519,698,304 - 19,763,363 (-)Ensemblpanpan1.1panPan2
RHOBTB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1313,823,607 - 13,879,663 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl313,825,040 - 13,877,456 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha315,161,683 - 15,216,345 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0313,702,408 - 13,757,171 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl313,702,203 - 13,757,142 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1313,665,317 - 13,719,938 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0313,662,275 - 13,717,986 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0313,862,251 - 13,916,923 (-)NCBIUU_Cfam_GSD_1.0
RHOBTB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2102,334,741 - 102,394,882 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12102,334,747 - 102,395,134 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22106,219,692 - 106,280,134 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RHOBTB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1489,605,801 - 89,670,433 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl489,606,204 - 89,670,669 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604938,251,332 - 38,316,159 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rhobtb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474314,361,573 - 14,424,063 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000016558   ⟹   ENSSTOP00000014818
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365237,559,335 - 7,617,786 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000039074   ⟹   ENSSTOP00000032419
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365237,600,102 - 7,617,363 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000041947   ⟹   ENSSTOP00000028751
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365237,562,806 - 7,617,363 (-)Ensembl
RefSeq Acc Id: XM_005326149   ⟹   XP_005326206
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213169,374,619 - 169,432,762 (-)NCBI
SpeTri2.0NW_0049365237,562,054 - 7,618,372 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013359012   ⟹   XP_013214466
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213169,374,619 - 169,432,773 (-)NCBI
SpeTri2.0NW_0049365237,562,054 - 7,618,380 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040271939   ⟹   XP_040127873
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213169,374,619 - 169,432,780 (-)NCBI
RefSeq Acc Id: XP_013214466   ⟸   XM_013359012
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005326206   ⟸   XM_005326149
- Peptide Label: isoform X1
- UniProtKB: I3MRS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040127873   ⟸   XM_040271939
- Peptide Label: isoform X3
Ensembl Acc Id: ENSSTOP00000028751   ⟸   ENSSTOT00000041947
Ensembl Acc Id: ENSSTOP00000032419   ⟸   ENSSTOT00000039074
Ensembl Acc Id: ENSSTOP00000014818   ⟸   ENSSTOT00000016558
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016555 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016558.3 UniProtKB/TrEMBL
  ENSSTOT00000039074.1 UniProtKB/TrEMBL
  ENSSTOT00000041947.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rhobtb3 ENTREZGENE
PANTHER RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  SPECKLE-TYPE POZ PROTEIN UniProtKB/TrEMBL
Pfam BTB UniProtKB/TrEMBL
  Ras UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A287DFU7_ICTTR UniProtKB/TrEMBL
  I3MRS5 ENTREZGENE, UniProtKB/TrEMBL