Zfr2 (zinc finger RNA binding protein 2) - Rat Genome Database

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Gene: Zfr2 (zinc finger RNA binding protein 2) Ictidomys tridecemlineatus
Analyze
Symbol: Zfr2
Name: zinc finger RNA binding protein 2
RGD ID: 12650608
Description: ENCODES a protein that exhibits double-stranded RNA binding (inferred); nucleic acid binding (inferred); single-stranded RNA binding (inferred); ASSOCIATED WITH amenorrhea (ortholog); obesity (ortholog); RASopathy (ortholog); FOUND IN nucleus (inferred); precatalytic spliceosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC106145104; uncharacterized LOC106145104; zinc finger RNA binding protein 2, transcript variant X1; zinc finger RNA binding protein 2, transcript variant X2; zinc finger RNA-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,642,440 - 215,680,506 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,154,247 - 2,192,363 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,154,277 - 2,175,308 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)
obesity  (ISO)
RASopathy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zfr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,642,440 - 215,680,506 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,154,247 - 2,192,363 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,154,277 - 2,175,308 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,804,024 - 3,869,038 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,804,024 - 3,869,038 (-)EnsemblGRCh38hg38GRCh38
GRCh37193,804,022 - 3,869,036 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,755,022 - 3,820,027 (-)NCBINCBI36Build 36hg18NCBI36
Celera193,741,663 - 3,806,609 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,568,828 - 3,633,347 (-)NCBIHuRef
CHM1_1193,803,683 - 3,868,635 (-)NCBICHM1_1
T2T-CHM13v2.0193,783,293 - 3,848,231 (-)NCBIT2T-CHM13v2.0
Zfr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,068,967 - 81,087,957 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,068,989 - 81,087,957 (+)EnsemblGRCm39 Ensembl
GRCm381081,233,133 - 81,252,123 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,233,155 - 81,252,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,695,908 - 80,714,868 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,636,305 - 80,645,546 (+)NCBIMGSCv36mm8
Celera1082,253,516 - 82,272,470 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Zfr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,117,490 - 9,136,315 (-)NCBIGRCr8
mRatBN7.278,466,768 - 8,485,593 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,466,753 - 8,485,538 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0711,335,024 - 11,353,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,335,478 - 11,353,713 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,502,430 - 11,521,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,950,953 - 9,969,249 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,950,571 - 9,957,299 (-)NCBI
Celera76,655,092 - 6,673,732 (-)NCBICelera
Cytogenetic Map7q11NCBI
Zfr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,678,007 - 5,712,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,680,107 - 5,712,367 (-)NCBIChiLan1.0ChiLan1.0
ZFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,199,612 - 8,266,197 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,431,242 - 7,497,818 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,827,501 - 2,894,084 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,777,494 - 3,842,458 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,777,714 - 3,842,444 (-)Ensemblpanpan1.1panPan2
ZFR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,648,604 - 55,693,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,648,648 - 55,684,936 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,367,494 - 55,420,244 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,302,123 - 56,354,888 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,308,736 - 56,350,086 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,357,961 - 55,410,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,839,774 - 55,892,748 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,038,574 - 56,091,496 (+)NCBIUU_Cfam_GSD_1.0
ZFR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,845,921 - 74,900,054 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,845,912 - 74,899,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,461,614 - 75,510,443 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZFR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,560,845 - 3,626,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,560,961 - 3,591,183 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,622,003 - 4,688,344 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248286,432,167 - 6,464,781 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000021065   ⟹   ENSSTOP00000021162
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365882,154,247 - 2,192,363 (-)Ensembl
RefSeq Acc Id: XM_013361421   ⟹   XP_013216875
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118215,642,440 - 215,680,506 (+)NCBI
SpeTri2.0NW_0049365882,154,277 - 2,175,308 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013216875 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000021162.2
GenBank Protein KAG3280712 (Get FASTA)   NCBI Sequence Viewer  
  KAG3280713 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_013216875   ⟸   XM_013361421
- UniProtKB: I3N9W5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000021162   ⟸   ENSSTOT00000021065
Protein Domains
DZF


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025821 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000021065.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
  3.30.460.10 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro DZF_dom UniProtKB/TrEMBL
  DZF_dom_C UniProtKB/TrEMBL
  DZF_dom_N UniProtKB/TrEMBL
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/TrEMBL
  NT_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Zfr2 ENTREZGENE
PANTHER ZINC FINGER RNA-BINDING PROTEIN UniProtKB/TrEMBL
  ZINC FINGER RNA-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam DZF UniProtKB/TrEMBL
  DZF_C UniProtKB/TrEMBL
  zf-met UniProtKB/TrEMBL
PROSITE DZF UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
SMART DZF UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
  ZnF_U1 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt I3N9W5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-25 Zfr2  zinc finger RNA binding protein 2  LOC106145104  uncharacterized LOC106145104  Data merged from RGD:12600561 737654 PROVISIONAL