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Gene: LOC101966789 (V-type proton ATPase catalytic subunit A-like) Ictidomys tridecemlineatus

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Symbol:

LOC101966789 (Ensembl: ATP6V1A)

Name:

V-type proton ATPase catalytic subunit A-like (Ensembl:ATPase H+ transporting V1 subunit A)

RGD ID:

12532612

Description:

ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN ATP metabolic process (inferred); cellular response to increased oxygen levels (inferred); intracellular iron ion homeostasis (inferred); FOUND IN apical plasma membrane (inferred); ATPase complex (inferred); clathrin-coated vesicle membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	14,844,237 - 14,845,778 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936536	1,257,990 - 1,312,530 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	17,223,190 - 17,224,731 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC101966789	Squirrel	ATP metabolic process	involved_in	IEA	InterPro:IPR004100\|InterPro:IPR022878\|InterPro:IPR036121	150520179		InterPro	GO_REF:0000002
LOC101966789	Squirrel	cellular response to increased oxygen levels	involved_in	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	intracellular iron ion homeostasis	involved_in	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	monoatomic ion transport	involved_in	IEA	UniProtKB-KW:KW-0406	150520179		UniProt	GO_REF:0000043
LOC101966789	Squirrel	proton transmembrane transport	involved_in	IEA	PANTHER:PTN000389826	150520179		TreeGrafter	GO_REF:0000118
LOC101966789	Squirrel	proton transmembrane transport	involved_in	IEA	UniProtKB-KW:KW-0375	150520179		UniProt	GO_REF:0000043
LOC101966789	Squirrel	proton transmembrane transport	involved_in	IEA	InterPro:IPR004100\|InterPro:IPR005725\|InterPro:IPR036121	150520179		InterPro	GO_REF:0000002
LOC101966789	Squirrel	synaptic vesicle lumen acidification	involved_in	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC101966789	Squirrel	apical plasma membrane	located_in	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	ATPase complex	part_of	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	clathrin-coated vesicle membrane	located_in	IEA	UniProtKB-SubCell:SL-0071	150520179		UniProt	GO_REF:0000044
LOC101966789	Squirrel	cytoplasm	located_in	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	cytoplasm	located_in	IEA	ARBA:ARBA00026971	150520179		UniProt	GO_REF:0000117
LOC101966789	Squirrel	cytosol	located_in	IEA	UniProtKB:P38606\|UniProtKB:P50516\|ensembl:ENSMUSP00000110314\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	lysosomal membrane	located_in	IEA	PANTHER:PTN000389826	150520179		TreeGrafter	GO_REF:0000118
LOC101966789	Squirrel	membrane	located_in	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	microvillus	located_in	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	nucleoplasm	located_in	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	plasma membrane	located_in	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	presynapse	located_in	IEA	GO:0097401	150520179		GOC	GO_REF:0000108
LOC101966789	Squirrel	proton-transporting V-type ATPase complex	part_of	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	proton-transporting V-type ATPase, V1 domain	part_of	IEA	InterPro:IPR005725	150520179		InterPro	GO_REF:0000002
LOC101966789	Squirrel	proton-transporting V-type ATPase, V1 domain	part_of	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	secretory granule	located_in	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	vacuolar proton-transporting V-type ATPase, V1 domain	part_of	IEA	UniProtKB:P38606\|ensembl:ENSP00000273398	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
LOC101966789	Squirrel	ATP binding	enables	IEA	InterPro:IPR000194\|InterPro:IPR020003	150520179		InterPro	GO_REF:0000002
LOC101966789	Squirrel	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	150520179		UniProt	GO_REF:0000043
LOC101966789	Squirrel	ATP hydrolysis activity	enables	IEA	InterPro:IPR005725	150520179		InterPro	GO_REF:0000002
LOC101966789	Squirrel	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	150520179		UniProt	GO_REF:0000043
LOC101966789	Squirrel	proton-transporting ATPase activity, rotational mechanism	enables	IEA	PANTHER:PTN000389826	150520179		TreeGrafter	GO_REF:0000118
LOC101966789	Squirrel	proton-transporting ATPase activity, rotational mechanism	enables	IEA	UniProtKB:P50516\|ensembl:ENSMUSP00000110314	150520179		Ensembl	GO_REF:0000107
LOC101966789	Squirrel	proton-transporting ATPase activity, rotational mechanism	enables	IEA	InterPro:IPR005725\|InterPro:IPR022878	150520179		InterPro	GO_REF:0000002

PMID:22301074	PMID:30032202

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_013356796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_013356796 ⟹ XP_013212250

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	14,844,237 - 14,845,778 (+)	NCBI
SpeTri2.0	NW_004936488	17,223,190 - 17,224,731 (-)	NCBI

Sequence:

show sequence

GGTTGTTGACATTGGAAGAAGAAAATAAACAGAAAAGGAAGGAGAAAGAAAGGGAGGAAGAAAAGGTAAATTAACATGATGGATTTCTCCAAGCTACCCAAAATAATCGATGAAGATAAAGAAAGCAC
ATTTGGTTATGTTCATGGGGTCTCAGGGCCTGTGGTTACAGCCTGTGACATGGCAGGTGCAGCCATGTATGAGCTGGTAAGAGTGGGTCACAGTGAGTTGGTTGGAGAGATTATTTGATTGGAAGGTG
ACATGGCTACTATTCAGGTGTATGAAGAAACTTCTGGTGTATCTGTTGGAGACCCTGTACTCCGAACTGGAAAACCTCTCTCCGTTGAGCTTGGTCCTGGCATTATGGGAGCCATTTTTGATGGTATT
CAAAGACCTTTGTCAGATATCAGCAGTCAGACCCAAAGTATCTACATCCCCAGAGGAGTAAATGTGTCTGCTCTTAGCAGAGCTGTTAAATGGGATTTTACACCATGCAAAAACCTACGGGTTGGTAG
CCATATCACTGGTGGAGATATTTATGCAATTGTCAATGAGAACTCACTCATCAAACACAAAATCATGTTACCCCCACGAAATGGAGGAACTGTCACTTGTATTGCCCCACCTGGGAATTATGATACCT
CTGATGTTGTCTTGGAGCTTGAATTTGAAGGTATAAAGGAGAAGTTCAGCGTGGTCCAGGTATGGCCTGTTCGTCAAGTTCGTCCTGTCACTGAGAAGCTGCCAGCCAATCATCCTTTGCTGACTGGC
CAGAGAGTCCTTGGTGCCCTTTTTCTGTGTGTACAAGGTGGAACTACTGCTATCCCTGGAGCTTTTGGCTGTGGAAAGACGGTGATATCACAGTCTCTCTCCAAGTATTCCAGTAGTGATGTGATCAT
TTATGTAGGATGTGGTGAAAGGGGAAACGAGATGTCTGAAGTCCTCCGAGACTTCCCAGAGCTCACTATGGAAGTTGATGGTAAGGTAGAGTCAATCATGAAGAGGACAGCTTTAGTAGCCAATACCT
CCAATATGCCTGTTGCTGCTGGAGAAGCCTCTATTTATACTGGCATTACACTATCAGAATATTTCCGTGACATGGGCTACCATGTCAGTATGATGGCTGACTCTACCTCGAGATGGGCCGAGGCCCTT
AGAGAAATCTCAGGTCGCTTAGCTGAAATGCCTGCAGATAGTGGATATCCTGCATATCTTGGTGCACGTCTGGCTTCTTTCTATGAGCGAGCAGGCAGAGTGAAATGTCTTGGAAATCCTGAAAGAGA
AGGAAGTGTCAGCATTGTAGGAGCAGTTTCTCCACCTGGTGGTGATTTTTCTGATCCAGTTACATCTGCTACTCTTGGTATTGTTCAGGTGTTTTGGGGATTAGATAAGAAACTAGCCCAACGTAAGC
ATTTCCCCTCTGTCAACTGGCTCATCAGCTACAGCAAGTACATGCGTGCATTGGACGAGTACTATGACAAACATTTCACAGAGTTTGTTCCTCTGAGGACCAAAGCTAAGGAAATTCTTCAGGAAGAA
GAAGAC

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Protein RefSeqs	XP_013212250	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008478.3
	ENSSTOP00000028310.1

RefSeq Acc Id:

XP_013212250 ⟸ XM_013356796

- UniProtKB:

I3MDK8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MMDFSKLPKIIDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIXLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSAL
SRAVKWDFTPCKNLRVGSHITGGDIYAIVNENSLIKHKIMLPPRNGGTVTCIAPPGNYDTSDVVLELEFEGIKEKFSVVQVWPVRQVRPVTEKLPANHPLLTGQRVLGALFLCVQGGTTAIPGAFGCG
KTVISQSLSKYSSSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAGEASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLA
SFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEED

hide sequence

Protein Domains

ATP synthase A/B type C-terminal ATPase F1/V1/A1 complex alpha/beta subunit ATPase F1/V1/A1 complex alpha/beta subunit N- ATPsynthase alpha/beta subunit N-terminal extension

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009445	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009452.3	UniProtKB/TrEMBL
	ENSSTOT00000033763.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.30.20	UniProtKB/TrEMBL
	2.40.50.100	UniProtKB/TrEMBL
	Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3	UniProtKB/TrEMBL
	P-loop containing nucleotide triphosphate hydrolases	UniProtKB/TrEMBL
InterPro	ATP-synt_VA_C	UniProtKB/TrEMBL
	ATP-synth_a_Xtn	UniProtKB/TrEMBL
	ATP_synth_asu-like_sf	UniProtKB/TrEMBL
	ATPase_a/bsu_AS	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_N	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_N_sf	UniProtKB/TrEMBL
	ATPase_F1/V1/A1_a/bsu_nucl-bd	UniProtKB/TrEMBL
	ATPase_F1/V1_b/a_C	UniProtKB/TrEMBL
	ATPase_V1-cplx_asu	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	V-ATPase_asu	UniProtKB/TrEMBL
NCBI Gene	LOC101966789	ENTREZGENE
PANTHER	V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A	UniProtKB/TrEMBL
	V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A	UniProtKB/TrEMBL
Pfam	ATP-synt_ab	UniProtKB/TrEMBL
	ATP-synt_ab_N	UniProtKB/TrEMBL
	ATP-synt_ab_Xtn	UniProtKB/TrEMBL
	ATP-synt_VA_C	UniProtKB/TrEMBL
PROSITE	ATPASE_ALPHA_BETA	UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
Superfamily-SCOP	C-terminal domain of alpha and beta subunits of F1 ATP synthase	UniProtKB/TrEMBL
	N-terminal domain of alpha and beta subunits of F1 ATP synthase	UniProtKB/TrEMBL
	P-loop containing nucleoside triphosphate hydrolases	UniProtKB/TrEMBL
UniProt	A0A287D470_ICTTR	UniProtKB/TrEMBL
	I3MDK8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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