Hnf4g (hepatocyte nuclear factor 4 gamma)

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Gene: Hnf4g (hepatocyte nuclear factor 4 gamma) Ictidomys tridecemlineatus

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Symbol:

Hnf4g

Name:

hepatocyte nuclear factor 4 gamma

RGD ID:

12527449

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN cytosol (inferred); intercellular bridge (inferred); mitotic spindle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hepatocyte nuclear factor 4-gamma

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	55,478,667 - 55,609,805 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936648	3,943,626 - 3,968,622 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936648	3,943,632 - 3,968,550 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IEA)

steroid hormone receptor signaling pathway (IEA)

Cellular Component

cytosol (IEA)

intercellular bridge (IEA)

mitotic spindle (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

metal ion binding (IEA)

nuclear steroid receptor activity (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hnf4g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	55,478,667 - 55,609,805 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936648	3,943,626 - 3,968,622 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936648	3,943,632 - 3,968,550 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HNF4G
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	75,407,649 - 75,566,834 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	75,407,914 - 75,566,834 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	76,319,884 - 76,479,069 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	76,614,758 - 76,641,624 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	76,614,757 - 76,641,623	NCBI
Celera	8	72,447,027 - 72,473,891 (+)	NCBI		Celera
Cytogenetic Map	8	q21.13	NCBI
HuRef	8	71,939,833 - 71,966,703 (+)	NCBI		HuRef
CHM1_1	8	76,503,705 - 76,530,572 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	75,837,130 - 75,996,323 (+)	NCBI		T2T-CHM13v2.0

Hnf4g
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	3,573,090 - 3,724,863 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	3,573,084 - 3,724,860 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	3,508,030 - 3,659,800 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	3,508,030 - 3,658,052 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	3,508,030 - 3,659,800 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	3,493,753 - 3,643,025 (+)	NCBI		MGSCv36	mm8
Celera	3	3,597,238 - 3,748,931 (+)	NCBI		Celera
Cytogenetic Map	3	A1	NCBI
cM Map	3	1.82	NCBI

Hnf4g
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	99,792,942 - 99,943,811 (-)	NCBI		GRCr8
mRatBN7.2	2	97,885,773 - 98,036,650 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	97,887,432 - 98,036,592 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	104,468,305 - 104,616,180 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	102,589,371 - 102,737,257 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	97,617,327 - 97,765,461 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	100,225,880 - 100,372,710 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	100,225,888 - 100,372,252 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	119,961,786 - 120,108,045 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	100,367,290 - 100,518,496 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	100,312,845 - 100,331,225 (-)	NCBI
Celera	2	93,381,225 - 93,528,222 (-)	NCBI		Celera
Cytogenetic Map	2	q23	NCBI

Hnf4g
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	5,080,954 - 5,107,542 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955444	5,081,013 - 5,157,988 (-)	NCBI	ChiLan1.0	ChiLan1.0

HNF4G
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	91,157,513 - 91,312,414 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	66,785,277 - 66,940,105 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	71,947,924 - 72,102,934 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	73,666,576 - 73,743,437 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	73,716,604 - 73,743,865 (+)	Ensembl	panpan1.1		panPan2

HNF4G
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	23,683,380 - 23,801,799 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	23,732,339 - 23,801,519 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	23,943,412 - 24,064,667 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	23,789,896 - 23,912,012 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	23,841,379 - 23,910,074 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	23,850,614 - 23,972,215 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	23,884,966 - 24,006,588 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	24,237,724 - 24,359,110 (+)	NCBI		UU_Cfam_GSD_1.0

HNF4G
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	60,505,385 - 60,595,789 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	60,505,388 - 60,641,052 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

HNF4G
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	70,971,287 - 71,133,212 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	71,106,434 - 71,133,206 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	70,236,683 - 70,393,483 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hnf4g
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	15,648,466 - 15,683,973 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624744	15,648,463 - 15,797,403 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005335837	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000007182 ⟹ ENSSTOP00000006419

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936648	3,943,626 - 3,968,622 (+)	Ensembl

RefSeq Acc Id:

XM_005335837 ⟹ XP_005335894

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	55,478,667 - 55,505,007 (-)	NCBI
SpeTri2.0	NW_004936648	3,943,632 - 3,968,550 (+)	NCBI

Sequence:

show sequence

ATGAGGATATCAGAACCGATTCTGGACATGGACGTGGGAAATTACAGTGAAGTTTTGGACCCAA
ATTATACCACTTTGGAATTTGAAACGATGCAGATTTTATATAATTCAAATGATAGTTCTGCCCC
CGAGACAACAAGTATGAATACCACAGACAACGGTGTGGGTGTCAACTGTCTGTGTGCGATATGT
GGGGACAGAGCAACAGGAAAACACTATGGGGCATCGAGCTGTGACGGGTGCAAGGGCTTCTTTC
GACGCAGCATACGCAAGAGTCATGTTTATTCCTGCAGGTTCAGTCGCCAATGTGTTGTTGACAA
GGACAAAAGGAATCAATGTAGATACTGTCGATTAAGAAAGTGTTTTCGAGCAGGAATGAAAAAA
GAAGCTGTGCAAAATGAACGTGATAGAATAAGCACCAGAAGAAGCACATTCGATGGCAGCAATA
TCCCCTCCATAAACACACTGTCACAAGCTGAAATTCGGTCTCGCCAGATCTCAGCCTCAAGCCC
TGGGGTCAGCACTGACATAAATGTTAAGAAAATTGCAAGTATTGGTGATGTCTGCGAATCTATG
AAACAGCAGCTTTTAGTCTTGGTGGAATGGGCTAAATATATTCCTGCCTTCTGTGAGTTACCAC
TGGATGACCAGGTGGCCCTGTTGAGAGCTCATGCAGGGGAGCACTTACTGCTTGGAGCTACGAA
AAGATCCATGATGTATAAAGATATTTTGCTTTTGGGCAACAACTACGTCATTCACAGAAACAGC
TGTGAAGTCGAGATCAGCCGTGTGGCCAATCGGGTTCTCGATGAGCTTGTCCGACCATTTCAAG
AAATCCAGATTGATGACAATGAGTATGCTTGCTTGAAGGCAATTGTATTTTTTGACCCAGATGC
AAAAGGACTAAGTGACCCAGTAAAAATTAAGAACATGCGGTTCCAAGTGCAGATCAGTCTAGAG
GACTACATCAACGACAGGCAGTATGACTCCAGGGGCAGGTTTGGGGAGCTGCTCTTGCTCCTGC
CCACGCTGCAGAGCATCACCTGGCAAATGATCGAGCAAATACAATTTGTGAAGCTTTTTGGAAT
GGTTAAAATTGACAACCTGCTTCAGGAAATGCTACTGGGTGGTGCTTCCAATGATGGAAATCAT
CTTCATCATCCAATGCACCCACATTTGTCTCAAGACCCATTAACTGGACAAACTATACTTTTAA
GTCCCATGTCAACATTGGTTCATACGGACCAGATCTCAACTCCTGAAACCCCACTACCTTCACC
ACCACAAGGCTCTGGACAAGAACAGTACAAAATAGCTTCAAATCAAGCTTCAGTTATTTCACAC
CAGTCCCTCTCCAAACAAAAGCAATTGTGAGAATGTGTTTACTTCCGAATAGCACTGCACAAAT
GTGAAAGGCTTTTGGTCTTGAAATATCTCAGGATATAACTTTTGGCAAACTCTTAGCCAAGGCT
TCTTCATGGTGCTGTTATA

hide sequence

RefSeq Acc Id:

XM_040293929 ⟹ XP_040149863

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	55,480,058 - 55,609,805 (-)	NCBI

RefSeq Acc Id:

XM_040293930 ⟹ XP_040149864

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	55,480,058 - 55,562,196 (-)	NCBI

RefSeq Acc Id:

XM_040293931 ⟹ XP_040149865

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	55,480,058 - 55,600,494 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005335894	(Get FASTA)	NCBI Sequence Viewer
	XP_040149863	(Get FASTA)	NCBI Sequence Viewer
	XP_040149864	(Get FASTA)	NCBI Sequence Viewer
	XP_040149865	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006419.3
GenBank Protein	KAG3274000	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005335894 ⟸ XM_005335837

- Peptide Label:

isoform X1

- Sequence:

show sequence

MRISEPILDMDVGNYSEVLDPNYTTLEFETMQILYNSNDSSAPETTSMNTTDNGVGVNCLCAIC
GDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKK
EAVQNERDRISTRRSTFDGSNIPSINTLSQAEIRSRQISASSPGVSTDINVKKIASIGDVCESM
KQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNS
CEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQISLE
DYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGNH
LHHPMHPHLSQDPLTGQTILLSPMSTLVHTDQISTPETPLPSPPQGSGQEQYKIASNQASVISH
QSLSKQKQL

hide sequence

RefSeq Acc Id:	XP_040149863 ⟸ XM_040293929
- Peptide Label:	isoform X2
- UniProtKB:	I3M990 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040149865 ⟸ XM_040293931
- Peptide Label:	isoform X2
- UniProtKB:	I3M990 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040149864 ⟸ XM_040293930
- Peptide Label:	isoform X2
- UniProtKB:	I3M990 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000006419 ⟸ ENSSTOT00000007182

Protein Domains

NR LBD Nuclear receptor

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007181	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007182.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.565.10	UniProtKB/TrEMBL
	3.30.50.10	UniProtKB/TrEMBL
InterPro	HNF4-like_DBD	UniProtKB/TrEMBL
	HNF4_LBD	UniProtKB/TrEMBL
	NHR-like_dom_sf	UniProtKB/TrEMBL
	Nucl_hrmn_rcpt_lig-bd	UniProtKB/TrEMBL
	Nuclear_hormone_rcpt_NR2	UniProtKB/TrEMBL
	Nuclear_hrmn_rcpt	UniProtKB/TrEMBL
	Retinoid-X_rcpt/HNF4	UniProtKB/TrEMBL
	Znf_hrmn_rcpt	UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/TrEMBL
NCBI Gene	Hnf4g	ENTREZGENE
PANTHER	HEPATOCYTE NUCLEAR FACTOR 4-GAMMA	UniProtKB/TrEMBL
	NUCLEAR HORMONE RECEPTOR	UniProtKB/TrEMBL
Pfam	Hormone_recep	UniProtKB/TrEMBL
	zf-C4	UniProtKB/TrEMBL
PRINTS	RETINOIDXR	UniProtKB/TrEMBL
	STRDHORMONER	UniProtKB/TrEMBL
	STROIDFINGER	UniProtKB/TrEMBL
PROSITE	NR_LBD	UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_1	UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_2	UniProtKB/TrEMBL
SMART	HOLI	UniProtKB/TrEMBL
	ZnF_C4	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
	SSF48508	UniProtKB/TrEMBL
UniProt	I3M990	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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