LOC101974766 (S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1) - Rat Genome Database

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Gene: LOC101974766 (S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1) Ictidomys tridecemlineatus
Analyze
Symbol: LOC101974766
Name: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
RGD ID: 12476658
Description: ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); catalytic activity (inferred); FMN binding (inferred); INVOLVED IN tRNA processing (inferred); wybutosine biosynthetic process (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, transcript variant X1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, transcript variant X2; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog; Tyw1
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344126,712,462 - 126,820,989 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365437,217,265 - 7,324,083 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005328544   ⟹   XP_005328601
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344126,712,462 - 126,820,989 (+)NCBI
SpeTri2.0NW_0049365437,217,265 - 7,324,083 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013360085   ⟹   XP_013215539
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344126,712,462 - 126,820,989 (+)NCBI
SpeTri2.0NW_0049365437,217,265 - 7,324,083 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040278227   ⟹   XP_040134161
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344126,712,462 - 126,820,989 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005328601 (Get FASTA)   NCBI Sequence Viewer  
  XP_013215539 (Get FASTA)   NCBI Sequence Viewer  
  XP_040134161 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003654.3
GenBank Protein KAG3259745 (Get FASTA)   NCBI Sequence Viewer  
  KAG3259746 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_013215539   ⟸   XM_013360085
- Peptide Label: isoform X2
- UniProtKB: I3M3J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005328601   ⟸   XM_005328544
- Peptide Label: isoform X1
- UniProtKB: I3M3J7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040134161   ⟸   XM_040278227
- Peptide Label: isoform X3
- UniProtKB: I3M3J7 (UniProtKB/TrEMBL)
Protein Domains
Flavodoxin-like   Radical SAM core


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004067 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004074.3 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  3.40.50.360 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/TrEMBL
  rSAM UniProtKB/TrEMBL
  tRNA_wybutosine-synth UniProtKB/TrEMBL
  tRNA_wybutosine-synthase UniProtKB/TrEMBL
NCBI Gene LOC101974766 ENTREZGENE
PANTHER PTHR13930 UniProtKB/TrEMBL
  S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED UniProtKB/TrEMBL
Pfam Flavodoxin_1 UniProtKB/TrEMBL
  Radical_SAM UniProtKB/TrEMBL
  Wyosine_form UniProtKB/TrEMBL
PRINTS FLAVODOXIN UniProtKB/TrEMBL
PROSITE FLAVODOXIN_LIKE UniProtKB/TrEMBL
  RADICAL_SAM UniProtKB/TrEMBL
Superfamily-SCOP Radical SAM enzymes UniProtKB/TrEMBL
  SSF52218 UniProtKB/TrEMBL
UniProt I3M3J7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 LOC101974766  S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1  LOC101974766  S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase  Symbol and/or name change 5135510 APPROVED