Dnah8 (dynein axonemal heavy chain 8) - Rat Genome Database

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Gene: Dnah8 (dynein axonemal heavy chain 8) Ictidomys tridecemlineatus
Analyze
Symbol: Dnah8
Name: dynein axonemal heavy chain 8
RGD ID: 12461958
Description: ENCODES a protein that exhibits microtubule motor activity (ortholog); INVOLVED IN microtubule-based movement (inferred); ASSOCIATED WITH autistic disorder (ortholog); Ciliary Motility Disorders (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN sperm flagellum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein heavy chain 8, axonemal
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494643,060,279 - 43,367,749 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647620,592,440 - 20,888,779 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647620,592,440 - 20,888,692 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dnah8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494643,060,279 - 43,367,749 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647620,592,440 - 20,888,779 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647620,592,440 - 20,888,692 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38638,715,311 - 39,030,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl638,715,311 - 39,030,792 (+)EnsemblGRCh38hg38GRCh38
GRCh37638,683,087 - 38,998,568 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36638,798,530 - 39,106,545 (+)NCBINCBI36Build 36hg18NCBI36
Build 34638,798,875 - 39,106,279NCBI
Celera640,244,058 - 40,551,978 (+)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef638,400,956 - 38,716,941 (+)NCBIHuRef
CHM1_1638,685,221 - 39,001,286 (+)NCBICHM1_1
T2T-CHM13v2.0638,539,868 - 38,855,176 (+)NCBIT2T-CHM13v2.0
Dnah8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391730,845,909 - 31,094,736 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1730,843,328 - 31,096,339 (+)EnsemblGRCm39 Ensembl
GRCm381730,626,935 - 30,875,762 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1730,624,354 - 30,877,365 (+)EnsemblGRCm38mm10GRCm38
MGSCv371730,763,881 - 31,012,209 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361730,354,003 - 30,602,276 (+)NCBIMGSCv36mm8
MGSCv361729,838,877 - 30,090,362 (+)NCBIMGSCv36mm8
Celera1731,522,082 - 31,526,571 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.71NCBI
Dnah8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8208,694,371 - 8,948,849 (+)NCBIGRCr8
mRatBN7.2208,692,939 - 8,946,780 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl208,692,963 - 8,946,772 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0209,301,317 - 9,560,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl209,313,271 - 9,560,682 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02011,489,384 - 11,743,678 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4208,936,173 - 9,199,913 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1209,040,225 - 9,044,478 (+)NCBI
Celera2010,220,601 - 10,473,765 (+)NCBICelera
Cytogenetic Map20p12NCBI
Dnah8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554374,441,655 - 4,718,247 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554374,441,776 - 4,722,261 (-)NCBIChiLan1.0ChiLan1.0
DNAH8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2553,200,275 - 53,533,014 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1649,070,191 - 49,398,007 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0638,275,243 - 38,620,278 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1639,479,294 - 39,800,107 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl639,479,294 - 39,800,107 (+)Ensemblpanpan1.1panPan2
DNAH8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,617,638 - 7,972,842 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,617,592 - 7,972,842 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha127,633,513 - 7,996,722 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0128,087,226 - 8,450,952 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl128,087,202 - 8,450,923 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1127,621,355 - 7,978,214 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,698,858 - 8,056,005 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0127,804,404 - 8,161,427 (+)NCBIUU_Cfam_GSD_1.0
DNAH8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl734,188,145 - 34,479,623 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1734,197,185 - 34,479,640 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2739,271,575 - 39,569,428 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11733,110,149 - 33,427,553 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1733,110,289 - 33,419,519 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604438,678,484 - 39,033,129 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnah8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475419,260,168 - 19,522,032 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475419,260,042 - 19,528,071 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005318733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000005973   ⟹   ENSSTOP00000005341
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647620,592,440 - 20,888,779 (-)Ensembl
RefSeq Acc Id: XM_005318733   ⟹   XP_005318790
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494643,060,279 - 43,367,749 (+)NCBI
SpeTri2.0NW_00493647620,592,440 - 20,888,692 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005318790 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005341.3
GenBank Protein KAG3289390 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005318790   ⟸   XM_005318733
- UniProtKB: I3M718 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000005341   ⟸   ENSSTOT00000005973
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005829 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005973.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2620 UniProtKB/TrEMBL
  1.10.472.130 UniProtKB/TrEMBL
  1.10.8.1220 UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_6 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_fam UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/TrEMBL
  Dynein_heavy_linker UniProtKB/TrEMBL
  Dynein_heavy_tail UniProtKB/TrEMBL
  Dynein_linker_3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Dnah8 ENTREZGENE
PANTHER DYNEIN AXONEMAL HEAVY CHAIN 8 UniProtKB/TrEMBL
  MALE FERTILITY FACTOR KL5 UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/TrEMBL
  AAA_7 UniProtKB/TrEMBL
  AAA_8 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_1 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  DHC_N1 UniProtKB/TrEMBL
  DHC_N2 UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/TrEMBL
  PF12777 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3M718 ENTREZGENE, UniProtKB/TrEMBL