Slco1a2 (solute carrier organic anion transporter family member 1A2) - Rat Genome Database

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Gene: Slco1a2 (solute carrier organic anion transporter family member 1A2) Ictidomys tridecemlineatus
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Symbol: Slco1a2
Name: solute carrier organic anion transporter family member 1A2
RGD ID: 12449883
Description: ENCODES a protein that exhibits bile acid transmembrane transporter activity (ortholog); organic anion transmembrane transporter activity (ortholog); INVOLVED IN cellular response to xenobiotic stimulus (ortholog); response to estrogen (ortholog); sodium-independent organic anion transport (ortholog); ASSOCIATED WITH cholestasis (ortholog); Dubin-Johnson syndrome (ortholog); steatotic liver disease (ortholog); FOUND IN basal plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,520,070 - 87,639,751 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365485,507,085 - 5,562,624 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slco1a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,520,070 - 87,639,751 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365485,507,085 - 5,562,624 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLCO1A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,264,600 - 21,419,634 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,264,600 - 21,419,594 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,417,534 - 21,572,568 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,311,651 - 21,439,638 (-)NCBINCBI36Build 36hg18NCBI36
Celera1226,572,933 - 26,703,770 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,191,506 - 21,322,480 (-)NCBIHuRef
CHM1_11221,383,004 - 21,513,840 (-)NCBICHM1_1
T2T-CHM13v2.01221,143,252 - 21,298,332 (-)NCBIT2T-CHM13v2.0
Slco1a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396141,751,164 - 141,802,011 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6141,751,166 - 141,801,925 (-)EnsemblGRCm39 Ensembl
GRCm386141,805,438 - 141,856,284 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6141,805,440 - 141,856,199 (-)EnsemblGRCm38mm10GRCm38
MGSCv376141,753,961 - 141,804,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366141,767,846 - 141,818,577 (-)NCBIMGSCv36mm8
Celera6144,866,113 - 144,916,846 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map672.9NCBI
Slco1a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84176,441,104 - 176,495,846 (-)NCBIGRCr8
mRatBN7.24174,710,004 - 174,764,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4174,710,004 - 175,254,573 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4181,004,901 - 181,059,637 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04176,789,179 - 176,843,919 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04175,409,707 - 175,464,446 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04175,969,549 - 176,026,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4175,969,549 - 176,026,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,194,947 - 240,251,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4163,247,039 - 163,301,862 (-)NCBICelera
Cytogenetic Map4q44NCBI
Slco1a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541316,821,791 - 16,912,903 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541316,821,808 - 16,910,511 (+)NCBIChiLan1.0ChiLan1.0
SLCO1A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21075,401,236 - 75,536,815 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11275,397,631 - 75,533,213 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01264,963,090 - 65,029,673 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11267,566,060 - 67,632,608 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1267,566,066 - 67,632,608 (+)Ensemblpanpan1.1panPan2
SLCO1A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12726,279,654 - 26,398,000 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2726,279,547 - 26,425,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2720,058,574 - 20,176,858 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02726,605,157 - 26,724,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2726,605,242 - 26,759,510 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12726,468,383 - 26,586,911 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02726,446,981 - 26,565,625 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02719,763,081 - 19,881,755 (-)NCBIUU_Cfam_GSD_1.0
SLCO1A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl552,049,443 - 52,129,730 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1552,020,303 - 52,133,132 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2555,357,986 - 55,403,096 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLCO1A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,125,711 - 21,283,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,128,062 - 21,283,796 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606913,956,025 - 14,016,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slco1a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475217,495,717 - 17,606,838 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475217,496,923 - 17,606,726 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005328909   ⟹   XP_005328966
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,639,751 (+)NCBI
SpeTri2.0NW_0049365485,507,085 - 5,562,624 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280930   ⟹   XP_040136864
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,638,804 (+)NCBI
RefSeq Acc Id: XM_040280931   ⟹   XP_040136865
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,520,070 - 87,638,804 (+)NCBI
RefSeq Acc Id: XM_040280932   ⟹   XP_040136866
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,583,355 - 87,638,804 (+)NCBI
RefSeq Acc Id: XM_040280933   ⟹   XP_040136867
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,551,737 - 87,638,804 (+)NCBI
RefSeq Acc Id: XM_040280934   ⟹   XP_040136868
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,638,804 (+)NCBI
RefSeq Acc Id: XM_040280935   ⟹   XP_040136869
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,639,751 (+)NCBI
RefSeq Acc Id: XM_040280936   ⟹   XP_040136870
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,597,055 - 87,639,751 (+)NCBI
RefSeq Acc Id: XM_040280937   ⟹   XP_040136871
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,639,751 (+)NCBI
RefSeq Acc Id: XM_040280938   ⟹   XP_040136872
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,592,500 - 87,639,751 (+)NCBI
RefSeq Acc Id: XR_005731897
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,628,990 (+)NCBI
RefSeq Acc Id: XR_005731898
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,628,980 (+)NCBI
RefSeq Acc Id: XR_005731899
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,628,965 (+)NCBI
RefSeq Acc Id: XR_005731900
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494587,584,120 - 87,628,971 (+)NCBI
RefSeq Acc Id: XP_005328966   ⟸   XM_005328909
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040136865   ⟸   XM_040280931
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040136867   ⟸   XM_040280933
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040136866   ⟸   XM_040280932
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040136869   ⟸   XM_040280935
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040136871   ⟸   XM_040280937
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040136868   ⟸   XM_040280934
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040136864   ⟸   XM_040280930
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040136872   ⟸   XM_040280938
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040136870   ⟸   XM_040280936
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003535 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003543.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  OATP UniProtKB/TrEMBL
NCBI Gene Slco1a2 ENTREZGENE
PANTHER PTHR11388 UniProtKB/TrEMBL
  SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 UniProtKB/TrEMBL
Pfam OATP UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt I3M2H0_ICTTR UniProtKB/TrEMBL