Wfikkn1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1) - Rat Genome Database

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Gene: Wfikkn1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1) Ictidomys tridecemlineatus
Analyze
Symbol: Wfikkn1
Name: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
RGD ID: 12437694
Description: ENCODES a protein that exhibits receptor antagonist activity (inferred); serine-type endopeptidase inhibitor activity (inferred); transforming growth factor beta binding (inferred); INVOLVED IN muscle cell development (ortholog); roof of mouth development (ortholog); skeletal system development (ortholog); ASSOCIATED WITH epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); short-rib thoracic dysplasia 9 with or without polydactyly (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,273,468 - 112,277,650 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501371,384 - 373,859 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501371,328 - 375,271 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Wfikkn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,273,468 - 112,277,650 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501371,384 - 373,859 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501371,328 - 375,271 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WFIKKN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816630,985 - 634,117 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16629,239 - 634,117 (+)EnsemblGRCh38hg38GRCh38
GRCh3716680,985 - 684,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616621,013 - 624,117 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416621,012 - 624,117NCBI
Celera16881,146 - 884,250 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16602,311 - 605,379 (+)NCBIHuRef
CHM1_116680,850 - 683,953 (+)NCBICHM1_1
T2T-CHM13v2.016635,019 - 638,150 (+)NCBIT2T-CHM13v2.0
Wfikkn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,096,602 - 26,099,832 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,096,602 - 26,099,832 (-)EnsemblGRCm39 Ensembl
GRCm381725,877,628 - 25,880,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,877,628 - 25,880,858 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,014,573 - 26,017,803 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,605,228 - 25,608,458 (-)NCBIMGSCv36mm8
Celera1726,410,684 - 26,413,914 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.97NCBI
Wfikkn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,400,953 - 15,403,280 (-)NCBIGRCr8
mRatBN7.21014,896,442 - 14,898,770 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,896,378 - 14,899,863 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,635,433 - 19,637,760 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,124,311 - 19,126,638 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,624,649 - 14,626,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,243,429 - 15,245,757 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,243,429 - 15,245,757 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,056,372 - 15,058,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,141,826 - 15,144,154 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1014,565,306 - 14,567,634 (-)NCBICelera
Cytogenetic Map10q12NCBI
Wfikkn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,569,046 - 16,577,650 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,573,094 - 16,577,650 (-)NCBIChiLan1.0ChiLan1.0
WFIKKN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218869,496 - 874,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,653,362 - 4,658,288 (+)NCBINHGRI_mPanPan1
PanPan1.116643,764 - 647,044 (+)NCBIpanpan1.1PanPan1.1panPan2
WFIKKN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,934,105 - 39,937,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,934,068 - 39,936,628 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,197,722 - 41,201,278 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,276,276 - 40,279,832 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,276,277 - 40,278,783 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,964,800 - 39,968,355 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,924,986 - 39,928,542 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,404,167 - 40,407,723 (-)NCBIUU_Cfam_GSD_1.0
WFIKKN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,136,202 - 41,138,785 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,136,200 - 41,139,986 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
WFIKKN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15547,499 - 554,080 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5547,795 - 554,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,584,546 - 30,588,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wfikkn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,443,399 - 1,448,669 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,442,351 - 1,446,249 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005323650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000029401   ⟹   ENSSTOP00000017383
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936501371,384 - 373,859 (-)Ensembl
RefSeq Acc Id: XM_005323650   ⟹   XP_005323707
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344112,273,468 - 112,277,650 (-)NCBI
SpeTri2.0NW_004936501371,328 - 375,271 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005323707 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017383.1
GenBank Protein KAG3259283 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005323707   ⟸   XM_005323650
- UniProtKB: I3MZ37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000017383   ⟸   ENSSTOT00000029401
Protein Domains
BPTI/Kunitz inhibitor   Ig-like   Kazal-like   NTR   WAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028457 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029401.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.120 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.30.60.30 UniProtKB/TrEMBL
  4.10.410.10 UniProtKB/TrEMBL
  4.10.75.10 UniProtKB/TrEMBL
InterPro Elafin-like_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  Kunitz_BPTI UniProtKB/TrEMBL
  Kunitz_BPTI_sf UniProtKB/TrEMBL
  Netrin_domain UniProtKB/TrEMBL
  Prtase_inh_Kunz-CS UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
  WAP_dom UniProtKB/TrEMBL
NCBI Gene Wfikkn1 ENTREZGENE
PANTHER ACP24A4-RELATED UniProtKB/TrEMBL
  PTHR45938:SF6 UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  Kunitz_BPTI UniProtKB/TrEMBL
  WAP UniProtKB/TrEMBL
PRINTS BASICPTASE UniProtKB/TrEMBL
PROSITE BPTI_KUNITZ_1 UniProtKB/TrEMBL
  BPTI_KUNITZ_2 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  NTR UniProtKB/TrEMBL
  WAP UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00131 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  WAP UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF50242 UniProtKB/TrEMBL
  SSF57256 UniProtKB/TrEMBL
  SSF57362 UniProtKB/TrEMBL
UniProt I3MZ37 ENTREZGENE, UniProtKB/TrEMBL