SRP68 (signal recognition particle 68) - Rat Genome Database

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Gene: SRP68 (signal recognition particle 68) Canis lupus familiaris
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Symbol: SRP68
Name: signal recognition particle 68
RGD ID: 12350578
Description: ENCODES a protein that exhibits ribosome binding (ortholog); INVOLVED IN response to xenobiotic stimulus (inferred); SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Arsenic Poisoning (ortholog); Craniofacial Abnormalities (ortholog); Severe Congenital Neutropenia 10 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 68kDA subunit of signal recognition particle; Signal recognition particle 68 kDa protein; signal recognition particle subunit SRP68
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,567,613 - 4,604,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,237,938 - 5,274,617 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1702390   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SRP68
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,567,613 - 4,604,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,237,938 - 5,274,617 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBIUU_Cfam_GSD_1.0
SRP68
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381776,038,785 - 76,072,517 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1776,038,775 - 76,072,517 (-)EnsemblGRCh38hg38GRCh38
GRCh371774,034,866 - 74,068,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,546,786 - 71,580,202 (-)NCBINCBI36Build 36hg18NCBI36
Build 341771,546,785 - 71,580,202NCBI
Celera1770,625,234 - 70,658,709 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,460,472 - 69,494,337 (-)NCBIHuRef
CHM1_11774,099,778 - 74,133,532 (-)NCBICHM1_1
T2T-CHM13v2.01776,931,916 - 76,965,649 (-)NCBIT2T-CHM13v2.0
Srp68
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,135,992 - 116,165,043 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11116,135,992 - 116,165,043 (-)EnsemblGRCm39 Ensembl
GRCm3811116,245,166 - 116,274,217 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,245,166 - 116,274,217 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711116,106,480 - 116,135,531 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,061,256 - 116,090,307 (-)NCBIMGSCv36mm8
Celera11128,009,838 - 128,038,857 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.06NCBI
Srp68
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,980,089 - 102,006,913 (-)NCBIGRCr8
mRatBN7.210101,481,213 - 101,508,035 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,481,212 - 101,508,035 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,537,988 - 106,564,817 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,001,083 - 106,027,907 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,402,126 - 101,428,953 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010105,123,324 - 105,150,080 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,123,327 - 105,228,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,880,932 - 104,893,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.010104,791,132 - 104,818,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,359,742 - 106,387,284 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,374,244 - 106,401,790 (-)NCBI
Celera10100,054,016 - 100,080,844 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Srp68
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,178,184 - 6,222,388 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,178,184 - 6,220,255 (+)NCBIChiLan1.0ChiLan1.0
SRP68
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21992,080,303 - 92,114,306 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,905,515 - 96,939,413 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,985,207 - 70,019,313 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,539,484 - 75,572,358 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,539,484 - 75,573,436 (-)Ensemblpanpan1.1panPan2
Srp68
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,181,208 - 5,222,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,189,251 - 1,231,014 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,189,245 - 1,230,747 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRP68
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,367,863 - 5,406,347 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,368,354 - 5,402,491 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,346,094 - 5,357,765 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRP68
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,607,216 - 45,649,357 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,607,329 - 45,651,086 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,354,484 - 16,397,153 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srp68
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,928,628 - 5,978,879 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,931,332 - 5,978,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SRP68
369 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000008082   ⟹   ENSCAFP00000007483
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000063990   ⟹   ENSCAFP00000052812
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000078249   ⟹   ENSCAFP00000044915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845036168   ⟹   ENSCAFP00845028300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl95,237,938 - 5,274,617 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845036295   ⟹   ENSCAFP00845028405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl95,237,938 - 5,274,617 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845036394   ⟹   ENSCAFP00845028488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl95,237,961 - 5,274,613 (+)Ensembl
RefSeq Acc Id: NM_001003271   ⟹   NP_001003271
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,567,628 - 4,604,229 (+)NCBI
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBI
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBI
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBI
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBI
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001003271   ⟸   NM_001003271
- UniProtKB: A0A8C0LWP4 (UniProtKB/TrEMBL),   A0A8C0JZI7 (UniProtKB/TrEMBL),   A0A8P0SAL1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000044915   ⟸   ENSCAFT00000078249
Ensembl Acc Id: ENSCAFP00000052812   ⟸   ENSCAFT00000063990
Ensembl Acc Id: ENSCAFP00000007483   ⟸   ENSCAFT00000008082
Ensembl Acc Id: ENSCAFP00845028405   ⟸   ENSCAFT00845036295
Ensembl Acc Id: ENSCAFP00845028300   ⟸   ENSCAFT00845036168
Ensembl Acc Id: ENSCAFP00845028488   ⟸   ENSCAFT00845036394

Promoters
RGD ID:13684412
Promoter ID:EPDNEW_C2482
Type:initiation region
Name:SRP68_1
Description:signal recognition particle 68
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,567,608 - 4,567,668EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005027 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000966 UniProtKB/TrEMBL
  ENSCAFG00040001082 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00845020322 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008082.5 UniProtKB/TrEMBL
  ENSCAFT00000063990.2 UniProtKB/TrEMBL
  ENSCAFT00000078249.2 UniProtKB/TrEMBL
  ENSCAFT00030001690.1 UniProtKB/TrEMBL
  ENSCAFT00030001721.1 UniProtKB/TrEMBL
  ENSCAFT00040002094.1 UniProtKB/Swiss-Prot
  ENSCAFT00040002110.1 UniProtKB/TrEMBL
  ENSCAFT00845036168 ENTREZGENE
  ENSCAFT00845036168.1 UniProtKB/TrEMBL
  ENSCAFT00845036295.1 UniProtKB/TrEMBL
  ENSCAFT00845036394.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3450.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro SRP68 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRP68-RBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRP68_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403952 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene SRP68 ENTREZGENE
PANTHER PTHR12860 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SRP68 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF SRP68 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0JZI7 ENTREZGENE
  A0A8C0LWP4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0LYW2_CANLF UniProtKB/TrEMBL
  A0A8C0PQ16_CANLF UniProtKB/TrEMBL
  A0A8I3P5C8_CANLF UniProtKB/TrEMBL
  A0A8I3P8A8_CANLF UniProtKB/TrEMBL
  A0A8I3PK44_CANLF UniProtKB/TrEMBL
  A0A8P0P2H7_CANLF UniProtKB/TrEMBL
  A0A8P0SAL1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SY89_CANLF UniProtKB/TrEMBL
  Q00004 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:46808 ENTREZGENE