SRP68 (signal recognition particle 68) - Rat Genome Database

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Gene: SRP68 (signal recognition particle 68) Canis lupus familiaris
Analyze
Symbol: SRP68
Name: signal recognition particle 68
RGD ID: 12350578
Description: ENCODES a protein that exhibits ribosome binding (ortholog); INVOLVED IN response to xenobiotic stimulus (inferred); SRP-dependent cotranslational protein targeting to membrane (inferred); ASSOCIATED WITH Arsenic Poisoning (ortholog); Craniofacial Abnormalities (ortholog); skin disease (ortholog); FOUND IN signal recognition particle (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 68kDA subunit of signal recognition particle; Signal recognition particle 68 kDa protein; signal recognition particle subunit SRP68
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,567,613 - 4,604,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBI
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBI
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBI
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBI
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1702390  


Genomics

Comparative Map Data
SRP68
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,567,613 - 4,604,230 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBI
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBI
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBI
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBI
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBI
SRP68
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1776,038,775 - 76,072,517 (-)EnsemblGRCh38hg38GRCh38
GRCh381776,038,785 - 76,072,517 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371774,034,866 - 74,068,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,546,786 - 71,580,202 (-)NCBINCBI36hg18NCBI36
Build 341771,546,785 - 71,580,202NCBI
Celera1770,625,234 - 70,658,709 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1769,460,472 - 69,494,337 (-)NCBIHuRef
CHM1_11774,099,778 - 74,133,532 (-)NCBICHM1_1
Srp68
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,135,992 - 116,165,043 (-)NCBIGRCm39mm39
GRCm39 Ensembl11116,135,992 - 116,165,043 (-)Ensembl
GRCm3811116,245,166 - 116,274,217 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,245,166 - 116,274,217 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711116,106,480 - 116,135,531 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611116,061,256 - 116,090,307 (-)NCBImm8
Celera11128,009,838 - 128,038,857 (-)NCBICelera
Cytogenetic Map11E2NCBI
Srp68
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210101,481,213 - 101,508,035 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl10101,481,212 - 101,508,035 (-)Ensembl
Rnor_6.010105,123,324 - 105,150,080 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,123,327 - 105,228,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,880,932 - 104,893,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.010104,791,132 - 104,818,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,359,742 - 106,387,284 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,374,244 - 106,401,790 (-)NCBI
Celera10100,054,016 - 100,080,844 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Srp68
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,178,184 - 6,222,388 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,178,184 - 6,220,255 (+)NCBIChiLan1.0ChiLan1.0
SRP68
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11775,539,484 - 75,572,358 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,539,484 - 75,573,436 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01769,985,207 - 70,019,313 (-)NCBIMhudiblu_PPA_v0panPan3
Srp68
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,181,208 - 5,222,708 (+)NCBI
SpeTri2.0NW_0049365941,189,245 - 1,230,747 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRP68
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,367,863 - 5,406,347 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,368,354 - 5,402,491 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,346,094 - 5,357,765 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRP68
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,607,216 - 45,649,357 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,607,329 - 45,651,086 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607716,354,484 - 16,397,153 (+)NCBIVero_WHO_p1.0
Srp68
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248015,931,332 - 5,978,656 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 1 4
Low 5 5 18 6 6 6 5 6 12 8 6 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000008082   ⟹   ENSCAFP00000007483
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000063990   ⟹   ENSCAFP00000052812
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000078249   ⟹   ENSCAFP00000044915
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,567,628 - 4,604,229 (+)Ensembl
RefSeq Acc Id: NM_001003271   ⟹   NP_001003271
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,567,628 - 4,604,229 (+)NCBI
Dog10K_Boxer_Tasha95,248,155 - 5,284,753 (+)NCBI
ROS_Cfam_1.095,237,963 - 5,274,616 (+)NCBI
UMICH_Zoey_3.195,277,889 - 5,314,511 (+)NCBI
UNSW_CanFamBas_1.095,387,171 - 5,423,963 (+)NCBI
UU_Cfam_GSD_1.095,447,876 - 5,484,483 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003271 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA37773 (Get FASTA)   NCBI Sequence Viewer  
  Q00004 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003271   ⟸   NM_001003271
- UniProtKB: Q00004 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000044915   ⟸   ENSCAFT00000078249
RefSeq Acc Id: ENSCAFP00000052812   ⟸   ENSCAFT00000063990
RefSeq Acc Id: ENSCAFP00000007483   ⟸   ENSCAFT00000008082

Promoters
RGD ID:13684412
Promoter ID:EPDNEW_C2482
Type:initiation region
Name:SRP68_1
Description:signal recognition particle 68
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,567,608 - 4,567,668EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005027 Ensembl
NCBI Gene SRP68 ENTREZGENE
UniProt Q00004 ENTREZGENE
VGNC ID VGNC:46808 ENTREZGENE