SPACA4 (sperm acrosome associated 4)

Gene: SPACA4 (sperm acrosome associated 4) Canis lupus familiaris

Analyze

Symbol:

SPACA4

Name:

sperm acrosome associated 4

RGD ID:

12304394

Description:

INVOLVED IN sperm-egg recognition (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sperm acrosome membrane-associated protein 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,700,222 - 107,701,257 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,700,586 - 107,700,936 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	107,221,649 - 107,222,676 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	108,224,221 - 108,225,248 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	108,224,585 - 108,224,935 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,890,748 - 107,891,775 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	107,538,041 - 107,539,068 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	108,373,753 - 108,374,780 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

sperm-egg recognition (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

References

Genomics

Comparative Map Data

SPACA4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,700,222 - 107,701,257 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,700,586 - 107,700,936 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	107,221,649 - 107,222,676 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	108,224,221 - 108,225,248 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	108,224,585 - 108,224,935 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,890,748 - 107,891,775 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	107,538,041 - 107,539,068 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	108,373,753 - 108,374,780 (-)	NCBI		UU_Cfam_GSD_1.0

SPACA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	48,606,742 - 48,607,714 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	48,606,742 - 48,607,714 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	49,109,999 - 49,110,971 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	53,801,812 - 53,802,783 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	53,801,811 - 53,802,782	NCBI
Celera	19	45,974,868 - 45,975,839 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	45,489,184 - 45,490,155 (+)	NCBI		HuRef
CHM1_1	19	49,111,855 - 49,112,826 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	51,600,842 - 51,601,814 (+)	NCBI		T2T-CHM13v2.0

Spaca4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	45,374,531 - 45,375,240 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	45,374,531 - 45,375,237 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,725,107 - 45,725,816 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,725,107 - 45,725,813 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,980,477 - 52,981,186 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	45,593,150 - 45,593,849 (-)	NCBI		MGSCv36	mm8
Celera	7	41,187,663 - 41,188,372 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.46	NCBI

Spaca4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	105,331,973 - 105,332,646 (-)	NCBI		GRCr8
mRatBN7.2	1	96,195,514 - 96,196,187 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	96,195,315 - 96,196,237 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	101,580,949 - 101,581,622 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	110,053,647 - 110,054,320 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	103,344,024 - 103,344,697 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,707,613 - 101,708,286 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,707,613 - 101,708,286 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,786,445 - 102,787,118 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	96,193,256 - 96,193,929 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	90,448,713 - 90,449,386 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Spaca4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,937,919 - 1,938,302 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,937,747 - 1,938,789 (-)	NCBI	ChiLan1.0	ChiLan1.0

SPACA4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	54,711,307 - 54,715,840 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	56,638,104 - 56,639,097 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	45,607,816 - 45,609,081 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	54,199,611 - 54,200,582 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	54,199,847 - 54,200,221 (+)	Ensembl	panpan1.1		panPan2

Spaca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,040,677 - 21,041,899 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936664	2,659,366 - 2,659,743 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPACA4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	53,968,485 - 53,968,865 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	53,968,485 - 53,968,865 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	49,715,807 - 49,716,187 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPACA4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	41,859,541 - 41,860,988 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	41,860,218 - 41,860,601 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	21,725,563 - 21,726,938 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Spaca4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624832	5,262,862 - 5,264,908 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SPACA4
4 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	hemolymphoid system	reproductive system	adipose tissue
High
Medium		8
Low	1		1
Below cutoff			1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038467648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038592652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038656442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_846975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000045741 ⟹ ENSCAFP00000040384

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	107,700,586 - 107,700,936 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845001851 ⟹ ENSCAFP00845001460

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	108,224,585 - 108,224,935 (-)	Ensembl

RefSeq Acc Id:

XM_038467648 ⟹ XP_038323576

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	107,890,748 - 107,891,775 (-)	NCBI

RefSeq Acc Id:

XM_038528362 ⟹ XP_038384290

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	108,373,753 - 108,374,780 (-)	NCBI

RefSeq Acc Id:

XM_038592652 ⟹ XP_038448580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	1	107,538,041 - 107,539,068 (-)	NCBI

RefSeq Acc Id:

XM_038656442 ⟹ XP_038512370

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	108,224,221 - 108,225,248 (-)	NCBI

RefSeq Acc Id:

XM_846975 ⟹ XP_852068

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	107,700,222 - 107,701,257 (-)	NCBI
Dog10K_Boxer_Tasha	1	107,221,649 - 107,222,676 (-)	NCBI

Sequence:

show sequence

TCTGTGAGGTCACCCCATTCCGCTCCATATAGACTCCCATCAGGTAGTGGCCGCTGGCTTGTCT
CCGTCCTGGGGAAGCTTCTGAGACCCGAGGACTCTCAAGCAGTGGTCACAACGGAGTTCCCAAG
AGGGACGCGGAGCGTTGGGACCCGAGGACCCTCCAAGTGCTGACCCTGGGAGGCCAGACCAGGG
GCAAAAGTCTCGTGGGCCTCAGGAGCGTCATTCAGCAGTTCCGGGAGGCCCAGGAAGCCCACGG
CCTGGCTTGGGCACCGTCACCGCCGCCAGGCCACCATGGTCCTCGGCTGGCTGCTGCTTCTGGC
AATGGCTCTGCCCCCGGGCACCACAGGCGCCAAGGACTGTGTGTTCTGTGAGCTGACCGATTCC
AAGCAGTGTCCCGGCATCCACATGCAGTGTGGCGACGATGAGGACTGCTTCACAGGCCATGGGG
TGGCTCCAGGCCTCGGCCCTATCATCAACAAAGGTTGCCTGCTGTCCACTTCTTGCGGCCACGA
GGAGCCGGTCACCTACATGGGTGTCACCTACACGCTTACCACCACGTGCTGCTACGGCCACATG
TGTAACAGGGCCCCCAGTCCCGCCAGATGGGAGGGGCGGGCCGCCGGCCTGGCGCTGGGTGTGC
TGCTGCTGCTGCTGCTTCCACGTTTGCTGTGACCAACCTGAAGGGCAGGACCTGGGACTGGTGT
CCCGGCTCCGCTGCTCCCCGAGCCCCCCGCCTCCACCCCTTCTCCCCATTAAATGGCCAGAGGC
CCTGGACAACCTCTTGTGGCCCCGGCTTCATCCATTCTAGGGCTGTCCACCCGGAGCCCAGTGC
TCGGCGAAGCATCCTCAGGCCTTATTCAGTGGTGGGGAGCCATGCTTGGTGGGTTTGGCTGTAC
CCCTACTGTATTTCATTGGTTCTAAGACGCGTATCTTTTCACATTTCGATCAGGATGCTTCTTT
TCATTGGTGGCACCTCAGAGTCGATGAAATATGGTTAAAACGAACAATGACAATAATAAATGAC
AGCTGATGTTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038323576	(Get FASTA)	NCBI Sequence Viewer
	XP_038384290	(Get FASTA)	NCBI Sequence Viewer
	XP_038448580	(Get FASTA)	NCBI Sequence Viewer
	XP_038512370	(Get FASTA)	NCBI Sequence Viewer
	XP_852068	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000040384.2
	ENSCAFP00030019951.1
	ENSCAFP00040002073.1
	ENSCAFP00845001460
	ENSCAFP00845001460.1

RefSeq Acc Id:	XP_852068 ⟸ XM_846975
- UniProtKB:	A0A8C0LLZ8 (UniProtKB/TrEMBL), A0A8C0PPB1 (UniProtKB/TrEMBL), A0A8I3MHK2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLGWLLLLAMALPPGTTGAKDCVFCELTDSKQCPGIHMQCGDDEDCFTGHGVAPGLGPIINKG CLLSTSCGHEEPVTYMGVTYTLTTTCCYGHMCNRAPSPARWEGRAAGLALGVLLLLLLPRLL hide sequence

RefSeq Acc Id:

ENSCAFP00000040384 ⟸ ENSCAFT00000045741

RefSeq Acc Id:

XP_038323576 ⟸ XM_038467648

RefSeq Acc Id:

XP_038448580 ⟸ XM_038592652

RefSeq Acc Id:	XP_038512370 ⟸ XM_038656442
- UniProtKB:	A0A8C0LLZ8 (UniProtKB/TrEMBL), A0A8C0PPB1 (UniProtKB/TrEMBL), A0A8I3MHK2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384290 ⟸ XM_038528362
- UniProtKB:	A0A8C0LLZ8 (UniProtKB/TrEMBL), A0A8C0PPB1 (UniProtKB/TrEMBL), A0A8I3MHK2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845001460 ⟸ ENSCAFT00845001851

Protein Domains

UPAR/Ly6

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000030190	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030012356	UniProtKB/TrEMBL
	ENSCAFG00040001292	UniProtKB/TrEMBL
	ENSCAFG00845001076	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000045741.3	UniProtKB/TrEMBL
	ENSCAFT00030022868.1	UniProtKB/TrEMBL
	ENSCAFT00040002422.1	UniProtKB/TrEMBL
	ENSCAFT00845001851	ENTREZGENE
	ENSCAFT00845001851.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.60.10	UniProtKB/TrEMBL
InterPro	LY6_UPA_recep-like	UniProtKB/TrEMBL
	Snake_toxin-like_sf	UniProtKB/TrEMBL
	SPACA4/Bouncer	UniProtKB/TrEMBL
NCBI Gene	SPACA4	ENTREZGENE
PANTHER	PTHR47613	UniProtKB/TrEMBL
	SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 4	UniProtKB/TrEMBL
Pfam	UPAR_LY6	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57302	UniProtKB/TrEMBL
UniProt	A0A8C0LLZ8	ENTREZGENE
	A0A8C0PPB1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MHK2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:53989	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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