MRNIP (MRN complex interacting protein)

Gene: MRNIP (MRN complex interacting protein) Canis lupus familiaris

Analyze

Symbol:

MRNIP

Name:

MRN complex interacting protein

RGD ID:

12304277

Description:

ENCODES a protein that exhibits chromatin binding (inferred); INVOLVED IN DNA damage response (ortholog); positive regulation of double-strand break repair via homologous recombination (ortholog); protein localization to chromatin (ortholog); ASSOCIATED WITH neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset (ortholog); Paget's disease of bone (ortholog); Paget's disease of bone 3 (ortholog); FOUND IN Mre11 complex (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

C11H5orf45; UPF0544 protein C5orf45 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	1,834,148 - 1,859,601 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	1,833,967 - 1,859,347 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	1,958,309 - 1,982,890 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	1,808,699 - 1,833,761 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	1,808,699 - 1,833,922 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	1,780,325 - 1,805,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	1,859,614 - 1,884,635 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	2,099,778 - 2,124,819 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset (ISO)

Paget's disease of bone (ISO)

Paget's disease of bone 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (ISO)

mitotic G2 DNA damage checkpoint signaling (IEA)

positive regulation of double-strand break repair via homologous recombination (ISO)

protein localization to chromatin (ISO)

regulation of double-strand break repair via nonhomologous end joining (ISO)

response to ionizing radiation (ISO)

Cellular Component

Mre11 complex (ISO)

nucleoplasm (ISO)

nucleus (IEA)

Molecular Function

chromatin binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

MRNIP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	1,834,148 - 1,859,601 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	1,833,967 - 1,859,347 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	1,958,309 - 1,982,890 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	1,808,699 - 1,833,761 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	1,808,699 - 1,833,922 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	1,780,325 - 1,805,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	1,859,614 - 1,884,635 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	2,099,778 - 2,124,819 (+)	NCBI		UU_Cfam_GSD_1.0

MRNIP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	179,837,276 - 179,858,817 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	179,835,133 - 179,862,173 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	179,264,276 - 179,285,817 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	179,196,872 - 179,218,446 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	174,889,422 - 174,910,994 (-)	NCBI		Celera
Cytogenetic Map	5	q35.3	NCBI
HuRef	5	173,989,434 - 174,010,598 (-)	NCBI		HuRef
CHM1_1	5	178,696,682 - 178,718,180 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	180,392,487 - 180,413,966 (-)	NCBI		T2T-CHM13v2.0

Mrnip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	50,065,678 - 50,090,943 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	50,065,271 - 50,090,942 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	50,174,851 - 50,200,116 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	50,174,444 - 50,200,115 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	49,988,353 - 50,013,617 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	50,018,274 - 50,043,532 (+)	NCBI		MGSCv36	mm8
Celera	11	54,735,207 - 54,760,524 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	30.33	NCBI

Mrnip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	35,002,440 - 35,026,555 (+)	NCBI		GRCr8
mRatBN7.2	10	34,501,359 - 34,525,474 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	34,501,384 - 34,525,469 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	39,176,664 - 39,200,837 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	7,715,913 - 7,740,090 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	34,170,346 - 34,194,510 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	35,680,687 - 35,704,685 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	35,680,658 - 35,704,776 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	35,439,501 - 35,463,129 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	35,724,312 - 35,751,257 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	33,850,558 - 33,874,637 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Mrnip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955408	726,124 - 758,851 (+)	NCBI	ChiLan1.0	ChiLan1.0

MRNIP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	174,778,668 - 174,808,973 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	172,918,205 - 172,948,512 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	174,989,967 - 175,020,550 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	182,299,111 - 182,340,717 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	182,299,016 - 182,340,632 (-)	Ensembl	panpan1.1		panPan2

Mrnip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	119,716,876 - 119,745,256 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936739	926,678 - 955,024 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRNIP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	78,730,611 - 78,753,152 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	80,296,670 - 80,319,204 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRNIP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	81,571,083 - 81,590,906 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	81,571,199 - 81,590,815 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	12,950,414 - 12,971,168 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mrnip
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624733	42,699,950 - 42,718,623 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in MRNIP
166 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium			7						7		3
Low	5	5	15	6	6	6	6	6	5	8	7	6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005626295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005626300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038489733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038551752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038615640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038681119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038681120	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038681121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038681122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038681123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000000570 ⟹ ENSCAFP00000000518

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	11	1,833,967 - 1,859,347 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000082509 ⟹ ENSCAFP00000056155

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	11	1,833,967 - 1,859,347 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845013201 ⟹ ENSCAFP00845010258

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	1,808,699 - 1,833,922 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845013235 ⟹ ENSCAFP00845010284

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	11	1,808,699 - 1,833,922 (+)	Ensembl

RefSeq Acc Id:

XM_005626295 ⟹ XP_005626352

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	1,834,148 - 1,859,601 (+)	NCBI
Dog10K_Boxer_Tasha	11	1,958,309 - 1,982,890 (+)	NCBI

Sequence:

show sequence

CGCACGCGAGACGGCGGGGTCTAGAGGACCCTGCGCGCGGGCCGGAGGCTGCGCGGGGGCTGCT
GGGAGGGCGGCCGCAATGTCGTCGGCTCAGCGGGCTAGGGTGCTGCGGTGCTTCCGCTGTCGCC
TCTTCCAAGCACACCAGGAGAAAAAGAGTCTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCA
GTCATTTTTGCAGACTTATGGTGAGGGCTCTGGTGCTGACTGTAGATGCCATGTCCAAAAATTA
AATCTGCTGCAGGGACAGATTTCAGAGATATCACTCAGGTTTCTGGAAGAGCCTGTAAATGTTG
ATGAGGAAAATTCAGGGCCTGGGAATGCTGAGCATGAGAGTGTGCAGGAAAAACCTCAGTCCTC
AGAGAACCGCTGGCTGAAGTATCTGGAAAGAGACTCAAAAGAACTGGGAATGGAAGAAGGAGTG
TGTTTCAAGAGACAGTCTTTATCTGGGACAGAGACGCCAGACCCTCCCTTCAACACAGGCCTGC
CTAGAAAAAGGAAATGGAGCCAGAGCACAGTCCAGCCTTCACACAGCCCAGATGTCCAGAACGT
GAGTGACTCTGAGGTTACCTTGGAGCCCCAGAAGGACCATGCTGGCCTGGCAGGGAAGGTCAGA
GAAGATGGCAGTCACCAGAACAGGGGCACCAGGGAGCTTGCTGTTCCTCAGGGGGGTCCTCCAC
GTCCAGCCCCACAGGTCAGGGCCGTATCTTCCAAGTCTGAACAATTTCTTCTGCCGCCTGGAAA
TGGCCCCCGTGTGGACACAGGGCTCCCAGGAACCCTGGCAAAAAACCCTAGGCCATCCAGGGCA
GCACTGGCTGAGCAGGGGACCCTCTGGGCCCAGACCGTGAGCAAAGGGTGCCCCGGCAGGCCCT
GCAGTACACCCAAGCTTCCCTGGGCACCCCCCACACTCCTGTCCAGGTCCCAGAGGCCCTGCCT
AAAGACCTCCAAACAGCCCTGGGACACTGGTCCTCTGGCAAAGGGTAGACCCTTGGTCACAGGA
GGGCAGGAGCCCCCACTTGTGCGGCTGTGTGACCTCTTTAAAACTGGTGAGGACTTTGAGGATG
ACCTGTGAGCTGGAATTAGAATGTTACCAACACAGGCACAAGTTACATGAGCCCTGCTCCATTA
GGCGCCTCGGCCACTGAAAAGGGGCTCCCAGATTAGCTTTTAAATGGGACTGGGGGTGGGGGGC
ACCTGGATGGCTCAGGAGGCTAAGCATCTGCATCACAATCCTGGGGTCCTGGGATCAGCTGCTG
AGCAGGGAGCCTGCTTTTCCCTCTGCCCCCTCGCTTCCCCCTGCTCATGCTCTCTCTAGCTCAC
ACTCTCAAATAAAATCTTTTTAAAAAAAAACTGGACTAGGATGATTTATGGGAACTATCAAAAA
GGACAAACTATCAGGTCATCTCTGGTTGCAGCATCTTTGATTAAAGTGCTTTTACCATTTAATT
ACAGGTTGTTTACAACATAGCAATAGGATGGTTACAAAGGGATCTCCTTTTTAAAAGCAACAGG
TTTGGAAATGAAAGTAGAGTGGTTATGGAGCAGACAGCATTCTGTGAGCACTGGCCCCTCAGGA
CCACGGGATTCCAGAAGCCCAGTCCTGGGACTGCCCTGCCCTCCAGGACCTGTTCCTCCCCCAG
CTGACAGGATGTTGGTTGTACTCAGTCTAAACTTGGAGCCAATCAGGTTTCTAGCACAAAATCA
ACTACAGGTCAGCCTACTATTTGTCACTGAAAACAAAAAAAAAAAACAGAAG

hide sequence

RefSeq Acc Id:

XM_005626296 ⟹ XP_005626353

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	1,834,148 - 1,859,601 (+)	NCBI
Dog10K_Boxer_Tasha	11	1,958,309 - 1,982,890 (+)	NCBI

Sequence:

show sequence

CGCACGCGAGACGGCGGGGTCTAGAGGACCCTGCGCGCGGGCCGGAGGCTGCGCGGGGGCTGCT
GGGAGGGCGGCCGCAATGTCGTCGGCTCAGCGGGCTAGGGTGCTGCGGTGCTTCCGCTGTCGCC
TCTTCCAAGCACACCAGGAGAAAAAGAGTCTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCA
GTCATTTTTGCAGGAAAAACCTCAGTCCTCAGAGAACCGCTGGCTGAAGTATCTGGAAAGAGAC
TCAAAAGAACTGGGAATGGAAGAAGGAGTGTGTTTCAAGAGACAGTCTTTATCTGGGACAGAGA
CGCCAGACCCTCCCTTCAACACAGGCCTGCCTAGAAAAAGGAAATGGAGCCAGAGCACAGTCCA
GCCTTCACACAGCCCAGATGTCCAGAACGTGAGTGACTCTGAGGTTACCTTGGAGCCCCAGAAG
GACCATGCTGGCCTGGCAGGGAAGGTCAGAGAAGATGGCAGTCACCAGAACAGGGGCACCAGGG
AGCTTGCTGTTCCTCAGGGGGGTCCTCCACGTCCAGCCCCACAGGTCAGGGCCGTATCTTCCAA
GTCTGAACAATTTCTTCTGCCGCCTGGAAATGGCCCCCGTGTGGACACAGGGCTCCCAGGAACC
CTGGCAAAAAACCCTAGGCCATCCAGGGCAGCACTGGCTGAGCAGGGGACCCTCTGGGCCCAGA
CCGTGAGCAAAGGGTGCCCCGGCAGGCCCTGCAGTACACCCAAGCTTCCCTGGGCACCCCCCAC
ACTCCTGTCCAGGTCCCAGAGGCCCTGCCTAAAGACCTCCAAACAGCCCTGGGACACTGGTCCT
CTGGCAAAGGGTAGACCCTTGGTCACAGGAGGGCAGGAGCCCCCACTTGTGCGGCTGTGTGACC
TCTTTAAAACTGGTGAGGACTTTGAGGATGACCTGTGAGCTGGAATTAGAATGTTACCAACACA
GGCACAAGTTACATGAGCCCTGCTCCATTAGGCGCCTCGGCCACTGAAAAGGGGCTCCCAGATT
AGCTTTTAAATGGGACTGGGGGTGGGGGGCACCTGGATGGCTCAGGAGGCTAAGCATCTGCATC
ACAATCCTGGGGTCCTGGGATCAGCTGCTGAGCAGGGAGCCTGCTTTTCCCTCTGCCCCCTCGC
TTCCCCCTGCTCATGCTCTCTCTAGCTCACACTCTCAAATAAAATCTTTTTAAAAAAAAACTGG
ACTAGGATGATTTATGGGAACTATCAAAAAGGACAAACTATCAGGTCATCTCTGGTTGCAGCAT
CTTTGATTAAAGTGCTTTTACCATTTAATTACAGGTTGTTTACAACATAGCAATAGGATGGTTA
CAAAGGGATCTCCTTTTTAAAAGCAACAGGTTTGGAAATGAAAGTAGAGTGGTTATGGAGCAGA
CAGCATTCTGTGAGCACTGGCCCCTCAGGACCACGGGATTCCAGAAGCCCAGTCCTGGGACTGC
CCTGCCCTCCAGGACCTGTTCCTCCCCCAGCTGACAGGATGTTGGTTGTACTCAGTCTAAACTT
GGAGCCAATCAGGTTTCTAGCACAAAATCAACTACAGGTCAGCCTACTATTTGTCACTGAAAAC
AAAAAAAAAAAACAGAAG

hide sequence

RefSeq Acc Id:

XM_005626298 ⟹ XP_005626355

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	1,850,427 - 1,859,601 (+)	NCBI
Dog10K_Boxer_Tasha	11	1,974,127 - 1,982,890 (+)	NCBI

Sequence:

show sequence

GCCTAGAAAAAGGTGCCAAACAAGTCACTAATCCAGCAGCCATCACCCCATACCCACGGTGACC
CACGATGGGGGCAGTGATGAGCAGCCCTAGCAGTCAGCAGCACAGAAGAAGCCTGCATGGCACT
AGCTGGCAGGAAATGGAGCCAGAGCACAGTCCAGCCTTCACACAGCCCAGATGTCCAGAACGTG
AGTGACTCTGAGGTTACCTTGGAGCCCCAGAAGGACCATGCTGGCCTGGCAGGGAAGGTCAGAG
AAGATGGCAGTCACCAGAACAGGGGCACCAGGGAGCTTGCTGTTCCTCAGGGGGGTCCTCCACG
TCCAGCCCCACAGGTCAGGGCCGTATCTTCCAAGTCTGAACAATTTCTTCTGCCGCCTGGAAAT
GGCCCCCGTGTGGACACAGGGCTCCCAGGAACCCTGGCAAAAAACCCTAGGCCATCCAGGGCAG
CACTGGCTGAGCAGGGGACCCTCTGGGCCCAGACCGTGAGCAAAGGGTGCCCCGGCAGGCCCTG
CAGTACACCCAAGCTTCCCTGGGCACCCCCCACACTCCTGTCCAGGTCCCAGAGGCCCTGCCTA
AAGACCTCCAAACAGCCCTGGGACACTGGTCCTCTGGCAAAGGGTAGACCCTTGGTCACAGGAG
GGCAGGAGCCCCCACTTGTGCGGCTGTGTGACCTCTTTAAAACTGGTGAGGACTTTGAGGATGA
CCTGTGAGCTGGAATTAGAATGTTACCAACACAGGCACAAGTTACATGAGCCCTGCTCCATTAG
GCGCCTCGGCCACTGAAAAGGGGCTCCCAGATTAGCTTTTAAATGGGACTGGGGGTGGGGGGCA
CCTGGATGGCTCAGGAGGCTAAGCATCTGCATCACAATCCTGGGGTCCTGGGATCAGCTGCTGA
GCAGGGAGCCTGCTTTTCCCTCTGCCCCCTCGCTTCCCCCTGCTCATGCTCTCTCTAGCTCACA
CTCTCAAATAAAATCTTTTTAAAAAAAAACTGGACTAGGATGATTTATGGGAACTATCAAAAAG
GACAAACTATCAGGTCATCTCTGGTTGCAGCATCTTTGATTAAAGTGCTTTTACCATTTAATTA
CAGGTTGTTTACAACATAGCAATAGGATGGTTACAAAGGGATCTCCTTTTTAAAAGCAACAGGT
TTGGAAATGAAAGTAGAGTGGTTATGGAGCAGACAGCATTCTGTGAGCACTGGCCCCTCAGGAC
CACGGGATTCCAGAAGCCCAGTCCTGGGACTGCCCTGCCCTCCAGGACCTGTTCCTCCCCCAGC
TGACAGGATGTTGGTTGTACTCAGTCTAAACTTGGAGCCAATCAGGTTTCTAGCACAAAATCAA
CTACAGGTCAGCCTACTATTTGTCACTGAAAACAAAAAAAAAAAACAGAAG

hide sequence

RefSeq Acc Id:

XM_005626299 ⟹ XP_005626356

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	11	1,834,148 - 1,858,568 (+)	NCBI
Dog10K_Boxer_Tasha	11	1,958,309 - 1,982,275 (+)	NCBI

Sequence:

show sequence

CGCACGCGAGACGGCGGGGTCTAGAGGACCCTGCGCGCGGGCCGGAGGCTGCGCGGGGGCTGCT
GGGAGGGCGGCCGCAATGTCGTCGGCTCAGCGGGCTAGGGTGCTGCGGTGCTTCCGCTGTCGCC
TCTTCCAAGCACACCAGGAGAAAAAGAGTCTCAAGTGGACATGCAAAGCTTGTGGAGAGAAGCA
GTCATTTTTGCAGACTTATGGTGAGGGCTCTGGTGCTGACTGTAGATGCCATGTCCAAAAATTA
AATCTGCTGCAGGGACAGATTTCAGAGATATCACTCAGGTTTCTGGAAGAGCCTGTAAATGTTG
ATGAGGAAAATTCAGGGCCTGGGAATGCTGAGCATGAGAGTGTGCAGGAAAAACCTCAGTCCTC
AGAGAACCGCTGGCTGAAGTATCTGGAAAGAGACTCAAAAGAACTGGGAATGGAAGAAGGAGTG
TGTTTCAAGAGACAGTCTTTATCTGGGACAGAGACGCCAGACCCTCCCTTCAACACAGGCCTGC
CTAGAAAAAGGAAATGGAGCCAGAGCACAGTCCAGCCTTCACACAGCCCAGATGTCCAGAACGT
GAGTGACTCTGAGGTTACCTTGGAGCCCCAGAAGCCTTGGATGGGGGCACTGTCCAGCCAGTCA
TTGCTTTCACACTCCTGATTCCTGGTCGTGGAACCTGGCAGAGGAGTTGAGGACCATGCTGGCC
TGGCAGGGAAGGTCAGAGAAGATGGCAGTCACCAGAACAGGGGCACCAGGGAGCTTGCTGTTCC
TCAGGGGGGTCCTCCACGTCCAGCCCCACAGGTCAGGGCCGTATCTTCCAAGTCTGAACA

hide sequence

RefSeq Acc Id:

XM_038489729 ⟹ XP_038345657

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	1,780,325 - 1,805,364 (+)	NCBI

RefSeq Acc Id:

XM_038489730 ⟹ XP_038345658

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	1,780,325 - 1,805,364 (+)	NCBI

RefSeq Acc Id:

XM_038489731 ⟹ XP_038345659

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	1,780,390 - 1,805,364 (+)	NCBI

RefSeq Acc Id:

XM_038489732 ⟹ XP_038345660

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	1,796,601 - 1,805,364 (+)	NCBI

RefSeq Acc Id:

XM_038489733 ⟹ XP_038345661

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	11	1,780,325 - 1,804,749 (+)	NCBI

RefSeq Acc Id:

XM_038551748 ⟹ XP_038407676

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	2,099,778 - 2,124,819 (+)	NCBI

RefSeq Acc Id:

XM_038551749 ⟹ XP_038407677

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	2,099,778 - 2,124,819 (+)	NCBI

RefSeq Acc Id:

XM_038551750 ⟹ XP_038407678

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	2,099,843 - 2,124,819 (+)	NCBI

RefSeq Acc Id:

XM_038551751 ⟹ XP_038407679

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	2,116,056 - 2,124,819 (+)	NCBI

RefSeq Acc Id:

XM_038551752 ⟹ XP_038407680

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	11	2,099,778 - 2,124,204 (+)	NCBI

RefSeq Acc Id:

XM_038615636 ⟹ XP_038471564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	1,859,614 - 1,884,635 (+)	NCBI

RefSeq Acc Id:

XM_038615637 ⟹ XP_038471565

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	1,859,614 - 1,884,635 (+)	NCBI

RefSeq Acc Id:

XM_038615638 ⟹ XP_038471566

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	1,859,679 - 1,884,635 (+)	NCBI

RefSeq Acc Id:

XM_038615639 ⟹ XP_038471567

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	1,875,878 - 1,884,635 (+)	NCBI

RefSeq Acc Id:

XM_038615640 ⟹ XP_038471568

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	11	1,859,614 - 1,884,020 (+)	NCBI

RefSeq Acc Id:

XM_038664077 ⟹ XP_038520005

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	11	1,958,374 - 1,982,890 (+)	NCBI

RefSeq Acc Id:

XM_038681119 ⟹ XP_038537047

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	1,808,699 - 1,833,761 (+)	NCBI

RefSeq Acc Id:

XM_038681120 ⟹ XP_038537048

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	1,808,699 - 1,833,761 (+)	NCBI

RefSeq Acc Id:

XM_038681121 ⟹ XP_038537049

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	1,808,764 - 1,833,761 (+)	NCBI

RefSeq Acc Id:

XM_038681122 ⟹ XP_038537050

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	1,824,998 - 1,833,761 (+)	NCBI

RefSeq Acc Id:

XM_038681123 ⟹ XP_038537051

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	11	1,808,699 - 1,833,146 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005626352	(Get FASTA)	NCBI Sequence Viewer
	XP_005626353	(Get FASTA)	NCBI Sequence Viewer
	XP_005626355	(Get FASTA)	NCBI Sequence Viewer
	XP_005626356	(Get FASTA)	NCBI Sequence Viewer
	XP_038345657	(Get FASTA)	NCBI Sequence Viewer
	XP_038345658	(Get FASTA)	NCBI Sequence Viewer
	XP_038345659	(Get FASTA)	NCBI Sequence Viewer
	XP_038345660	(Get FASTA)	NCBI Sequence Viewer
	XP_038345661	(Get FASTA)	NCBI Sequence Viewer
	XP_038407676	(Get FASTA)	NCBI Sequence Viewer
	XP_038407677	(Get FASTA)	NCBI Sequence Viewer
	XP_038407678	(Get FASTA)	NCBI Sequence Viewer
	XP_038407679	(Get FASTA)	NCBI Sequence Viewer
	XP_038407680	(Get FASTA)	NCBI Sequence Viewer
	XP_038471564	(Get FASTA)	NCBI Sequence Viewer
	XP_038471565	(Get FASTA)	NCBI Sequence Viewer
	XP_038471566	(Get FASTA)	NCBI Sequence Viewer
	XP_038471567	(Get FASTA)	NCBI Sequence Viewer
	XP_038471568	(Get FASTA)	NCBI Sequence Viewer
	XP_038520005	(Get FASTA)	NCBI Sequence Viewer
	XP_038537047	(Get FASTA)	NCBI Sequence Viewer
	XP_038537048	(Get FASTA)	NCBI Sequence Viewer
	XP_038537049	(Get FASTA)	NCBI Sequence Viewer
	XP_038537050	(Get FASTA)	NCBI Sequence Viewer
	XP_038537051	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000000518.3
	ENSCAFP00000056155.1
	ENSCAFP00030011480.1
	ENSCAFP00030011510.1
	ENSCAFP00040013161.1
	ENSCAFP00040013169.1
	ENSCAFP00845010258.1
	ENSCAFP00845010284.1

RefSeq Acc Id:	XP_005626352 ⟸ XM_005626295
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JM88 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSAQRARVLRCFRCRLFQAHQEKKSLKWTCKACGEKQSFLQTYGEGSGADCRCHVQKLNLLQG QISEISLRFLEEPVNVDEENSGPGNAEHESVQEKPQSSENRWLKYLERDSKELGMEEGVCFKRQ SLSGTETPDPPFNTGLPRKRKWSQSTVQPSHSPDVQNVSDSEVTLEPQKDHAGLAGKVREDGSH QNRGTRELAVPQGGPPRPAPQVRAVSSKSEQFLLPPGNGPRVDTGLPGTLAKNPRPSRAALAEQ GTLWAQTVSKGCPGRPCSTPKLPWAPPTLLSRSQRPCLKTSKQPWDTGPLAKGRPLVTGGQEPP LVRLCDLFKTGEDFEDDL hide sequence

RefSeq Acc Id:

XP_005626353 ⟸ XM_005626296

- Peptide Label:

isoform X2

- Sequence:

show sequence

MSSAQRARVLRCFRCRLFQAHQEKKSLKWTCKACGEKQSFLQEKPQSSENRWLKYLERDSKELG
MEEGVCFKRQSLSGTETPDPPFNTGLPRKRKWSQSTVQPSHSPDVQNVSDSEVTLEPQKDHAGL
AGKVREDGSHQNRGTRELAVPQGGPPRPAPQVRAVSSKSEQFLLPPGNGPRVDTGLPGTLAKNP
RPSRAALAEQGTLWAQTVSKGCPGRPCSTPKLPWAPPTLLSRSQRPCLKTSKQPWDTGPLAKGR
PLVTGGQEPPLVRLCDLFKTGEDFEDDL

hide sequence

RefSeq Acc Id:	XP_005626356 ⟸ XM_005626299
- Peptide Label:	isoform X5
- UniProtKB:	A0A8C0MN01 (UniProtKB/TrEMBL), A0A8I3N5V0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSAQRARVLRCFRCRLFQAHQEKKSLKWTCKACGEKQSFLQTYGEGSGADCRCHVQKLNLLQG QISEISLRFLEEPVNVDEENSGPGNAEHESVQEKPQSSENRWLKYLERDSKELGMEEGVCFKRQ SLSGTETPDPPFNTGLPRKRKWSQSTVQPSHSPDVQNVSDSEVTLEPQKPWMGALSSQSLLSHS hide sequence

RefSeq Acc Id:	XP_005626355 ⟸ XM_005626298
- Peptide Label:	isoform X4
- Sequence:	show sequence MALAGRKWSQSTVQPSHSPDVQNVSDSEVTLEPQKDHAGLAGKVREDGSHQNRGTRELAVPQGG PPRPAPQVRAVSSKSEQFLLPPGNGPRVDTGLPGTLAKNPRPSRAALAEQGTLWAQTVSKGCPG RPCSTPKLPWAPPTLLSRSQRPCLKTSKQPWDTGPLAKGRPLVTGGQEPPLVRLCDLFKTGEDF EDDL hide sequence

RefSeq Acc Id:

ENSCAFP00000000518 ⟸ ENSCAFT00000000570

RefSeq Acc Id:

ENSCAFP00000056155 ⟸ ENSCAFT00000082509

RefSeq Acc Id:	XP_038345657 ⟸ XM_038489729
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038345658 ⟸ XM_038489730
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038345661 ⟸ XM_038489733
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038345659 ⟸ XM_038489731
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038345660 ⟸ XM_038489732
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038471564 ⟸ XM_038615636
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038471565 ⟸ XM_038615637
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038471568 ⟸ XM_038615640
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038471566 ⟸ XM_038615638
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038471567 ⟸ XM_038615639
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038537047 ⟸ XM_038681119
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JM88 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038537048 ⟸ XM_038681120
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038537051 ⟸ XM_038681123
- Peptide Label:	isoform X5
- UniProtKB:	A0A8C0MN01 (UniProtKB/TrEMBL), A0A8I3N5V0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038537049 ⟸ XM_038681121
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038537050 ⟸ XM_038681122
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038520005 ⟸ XM_038664077
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038407676 ⟸ XM_038551748
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JM88 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407677 ⟸ XM_038551749
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038407680 ⟸ XM_038551752
- Peptide Label:	isoform X5
- UniProtKB:	A0A8C0MN01 (UniProtKB/TrEMBL), A0A8I3N5V0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038407678 ⟸ XM_038551750
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038407679 ⟸ XM_038551751
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSCAFP00845010258 ⟸ ENSCAFT00845013201

RefSeq Acc Id:

ENSCAFP00845010284 ⟸ ENSCAFT00845013235

Protein Domains

MRN complex-interacting protein N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000000365	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030007089	UniProtKB/TrEMBL
	ENSCAFG00040008063	UniProtKB/TrEMBL
	ENSCAFG00845007488	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000000570.4	UniProtKB/TrEMBL
	ENSCAFT00000082509.2	UniProtKB/TrEMBL
	ENSCAFT00030013133.1	UniProtKB/TrEMBL
	ENSCAFT00030013168.1	UniProtKB/TrEMBL
	ENSCAFT00040015195.1	UniProtKB/TrEMBL
	ENSCAFT00040015202.1	UniProtKB/TrEMBL
	ENSCAFT00845013201.1	UniProtKB/TrEMBL
	ENSCAFT00845013235.1	UniProtKB/TrEMBL
InterPro	MRNIP	UniProtKB/TrEMBL
	MRNIP_N	UniProtKB/TrEMBL
NCBI Gene	MRNIP	ENTREZGENE
PANTHER	MRN COMPLEX-INTERACTING PROTEIN	UniProtKB/TrEMBL
	PTHR15863	UniProtKB/TrEMBL
Pfam	MRNIP	UniProtKB/TrEMBL
UniProt	A0A8C0JM88	ENTREZGENE
	A0A8C0MN01	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0S0E4_CANLF	UniProtKB/TrEMBL
	A0A8I3N2W8_CANLF	UniProtKB/TrEMBL
	A0A8I3N5V0	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:56068	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar