Advanced Search (OLGA)

Gene: THAP10 (THAP domain containing 10) Canis lupus familiaris

Analyze

Symbol:

THAP10

Name:

THAP domain containing 10

RGD ID:

12299949

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); sequence-specific DNA binding (inferred); INVOLVED IN endothelial cell proliferation (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

THAP domain-containing protein 10

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	34,571,371 - 34,580,697 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	34,505,209 - 34,514,970 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	34,772,072 - 34,781,747 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	34,772,079 - 34,781,716 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	34,717,726 - 34,728,606 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	34,756,595 - 34,766,566 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	35,008,658 - 35,018,438 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endothelial cell proliferation (IEA)

regulation of DNA-templated transcription (IEA)

Cellular Component

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA)

protein binding (ISO)

sequence-specific DNA binding (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

THAP10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	34,571,371 - 34,580,697 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	34,505,209 - 34,514,970 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	34,772,072 - 34,781,747 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	34,772,079 - 34,781,716 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	34,717,726 - 34,728,606 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	34,756,595 - 34,766,566 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	35,008,658 - 35,018,438 (-)	NCBI		UU_Cfam_GSD_1.0

THAP10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	70,881,342 - 70,892,433 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	70,881,342 - 70,892,433 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	71,173,681 - 71,184,772 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	68,960,735 - 68,971,807 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	68,960,734 - 68,971,807	NCBI
Celera	15	48,064,589 - 48,075,644 (-)	NCBI		Celera
Cytogenetic Map	15	q23	NCBI
HuRef	15	48,009,242 - 48,020,316 (-)	NCBI		HuRef
CHM1_1	15	71,291,945 - 71,303,036 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	68,704,629 - 68,715,718 (-)	NCBI		T2T-CHM13v2.0

THAP10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	60,144,858 - 60,155,804 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	64,308,781 - 64,319,718 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	49,830,820 - 49,841,919 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	68,597,315 - 68,608,402 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	68,597,315 - 68,608,402 (-)	Ensembl	panpan1.1		panPan2

Thap10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	112,564,495 - 112,568,288 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936471	30,415,017 - 30,416,343 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

THAP10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	12,568,451 - 12,578,691 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	12,567,865 - 12,579,870 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	128,909,546 - 128,920,800 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in THAP10
157 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038442829	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038517262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038580861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038580862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038645221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_848801	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845039726 ⟹ ENSCAFP00845031116

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	34,772,079 - 34,781,716 (-)	Ensembl

RefSeq Acc Id:

XM_038442829 ⟹ XP_038298757

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	34,772,072 - 34,781,747 (-)	NCBI

RefSeq Acc Id:

XM_038517262 ⟹ XP_038373190

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	30	34,717,726 - 34,728,606 (-)	NCBI

RefSeq Acc Id:

XM_038580861 ⟹ XP_038436789

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	30	35,008,658 - 35,018,438 (-)	NCBI

RefSeq Acc Id:

XM_038580862 ⟹ XP_038436790

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	30	35,008,658 - 35,018,438 (-)	NCBI

RefSeq Acc Id:

XM_038645221 ⟹ XP_038501149

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	30	34,756,595 - 34,766,566 (-)	NCBI

RefSeq Acc Id:

XM_848801 ⟹ XP_853894

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	30	34,571,371 - 34,580,697 (-)	NCBI
Dog10K_Boxer_Tasha	30	34,505,209 - 34,514,970 (-)	NCBI

Sequence:

show sequence

CGGGGACGCGGGGGCCGGGGGCCGGGGGCGCCGCCATGCCCGCCCGCTGCGTGGCCGCCCACTG
CGGCAACACCACCAAGTGCGGGAAGTCGCTGTTCCGCTTCCCCAAGGACCGGGCGGTGCGGCTG
CTGTGGGACCGCTTCGTGCGGGGCCGCCGCGCCGACTGGTACGGGGGCAACGACCGCTCGGTCA
TCTGCTCCGACCACTTCGCCCCCGCCTGCTTTGACGTGTCCTCGGTCCTCCAGAAGAACCTGCG
CTTCTCCCAGCGCCTGAGGCTCGTAGCGGGCGCCGTGCCCACCCTGCACCGGGGGACCGCCCCA
GCGCCCCGGGGCGACGGCGGCCGAGGGGGGGCGGGGCCCCCGGCGGACCCCGCGGCCCAGCCCG
CCCCGCCCCCGAGCCCAGCCCGCTGCGCGCGGCCCGGGGCCCGGAGGAGGGCCGCGCCCGCACA
GATTACATGTGAAAATGAAGTTAAACAAACACAAGTCCCTGCTAATAATCTATCTTATAGTGTC
ACTTCAGTACCTACTCACTGTGAAGAAGGCCCAGTGCATAAAAGTACACAGTTGTCTCTGAAAA
GGCCCCCTCACCGGAATGTTGGTATTCAGGCCAAAGTGAAAGTGTTTGGAACACAACTGTGTAA
TGCCACTACTCAGACTGACGGATTGCAGCCTAGGAGGAGCTCTCTCTTTGACATCTACTCCAGT
GACTCAGACCCAGATGCAGATTGGGATGTCAAGAGTGAGCAGAGCGATTTGTCCTACATAGCAG
TGCAAGTGAAAGAAGAGTCTTGCTAAAAATGCAACTCAAATGACTTGATGTGCTATAGATTTTC
AAATCTTCGCTCATATAATTATTTCTTTGCCCTTGTAAATCTTTCACTTTGGGATACTTGAATA
TCAGCAAAATGTGTTTAGCTCTAAGGCAAAAATATGCCCACCTGCCAAGATCATGAAGATTATC
CTGCCCACAAACCTCCCCACCTCCCACTTTCACCTCGTTTCTTTTTTCTTTTTATCCGTTTGGT
GGATATCGAGTTATAAAACAAAACCACGGTAGCAGCATTTCCAGATCAAGATTAAGCACTGAAT
ATTTAAGCTTAATGCAGAAGCAGCATTCATATGGGACTTATTTGACATTCACAAGTTAGAAGGT
CACTATCCTAAATAATTTGAAGATAATAGTAATCACAGCCAAGTCTGATACTATTAAATGATTT
GGGAGCCAGGAGACTCATCCTTGATTATTACTTTTTTATGTTGTATATTTATTAGTTTGTCCAT
TTGTAATACTGTTGGATCTGTGAATCGGTCCTTGTGAGCATTTCTGGTGAAGTTATGGCTCTTA
CAGAAAATTTTCAAAGGGAATTAATTTAAATAGAGATAGAGTTTCATGTACTTGGATTGCATTA
TTAATGAAATCTATTTGCATTGGTTCCTATTACAACAAACCAATTAGCTTGATTAATTTAGATT
GAAATTATTGACATGGAAAAAGAAAGTATTATATTTCTAACATATTCCTTTTCAAGAATTAAGT
TTTCCTCTATTAATACCTTTCTGTTGAATTCTACATTTGGGAAATAAGCATGTGAAACAGCTGT
CCCACCTGCCATTCACCAGGAAAATTTCTATGGCAACTCTGTACCATGAAGTAATTTGTTACAA
TGGTTTCTGAGAAACTTATTATAACTCTGATCTTCTATTGAGAATAAAAATAAATGTCCATTTT
GTACCTCATCTTGTTAGTTGTGCATGATTGGAAGAACTTGCATGCATTTTATTCTAGAAGGTTT
AAATAATATACCAAAGTGATTTTCTTCCTAATTTCATGTGTGACTTAATTTGAACAGTGTAATT
TTAATAAAAAGAATAATAAAATAAAATATTAATAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038298757	(Get FASTA)	NCBI Sequence Viewer
	XP_038373190	(Get FASTA)	NCBI Sequence Viewer
	XP_038436789	(Get FASTA)	NCBI Sequence Viewer
	XP_038436790	(Get FASTA)	NCBI Sequence Viewer
	XP_038501149	(Get FASTA)	NCBI Sequence Viewer
	XP_853894	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000041900.2
	ENSCAFP00845031116
	ENSCAFP00845031116.1

RefSeq Acc Id:	XP_853894 ⟸ XM_848801
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3PPE3 (UniProtKB/TrEMBL), A0A8P0NSS9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPARCVAAHCGNTTKCGKSLFRFPKDRAVRLLWDRFVRGRRADWYGGNDRSVICSDHFAPACFD VSSVLQKNLRFSQRLRLVAGAVPTLHRGTAPAPRGDGGRGGAGPPADPAAQPAPPPSPARCARP GARRRAAPAQITCENEVKQTQVPANNLSYSVTSVPTHCEEGPVHKSTQLSLKRPPHRNVGIQAK VKVFGTQLCNATTQTDGLQPRRSSLFDIYSSDSDPDADWDVKSEQSDLSYIAVQVKEESC hide sequence

RefSeq Acc Id:	XP_038373190 ⟸ XM_038517262
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038501149 ⟸ XM_038645221
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038298757 ⟸ XM_038442829
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I3PPE3 (UniProtKB/TrEMBL), A0A8P0NSS9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038436790 ⟸ XM_038580862
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3PPE3 (UniProtKB/TrEMBL), A0A8P0NSS9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038436789 ⟸ XM_038580861
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSCAFP00845031116 ⟸ ENSCAFT00845039726

Protein Domains

THAP-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000031771	UniProtKB/TrEMBL
	ENSCAFG00845022499	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000047191.4	UniProtKB/TrEMBL
	ENSCAFT00845039726	ENTREZGENE
	ENSCAFT00845039726.1	UniProtKB/TrEMBL
InterPro	THAP1/10	UniProtKB/TrEMBL
	THAP_Znf	UniProtKB/TrEMBL
NCBI Gene	THAP10	ENTREZGENE
PANTHER	THAP DOMAIN-CONTAINING	UniProtKB/TrEMBL
	THAP DOMAIN-CONTAINING PROTEIN 10	UniProtKB/TrEMBL
Pfam	THAP	UniProtKB/TrEMBL
PROSITE	ZF_THAP	UniProtKB/TrEMBL
SMART	DM3	UniProtKB/TrEMBL
	THAP	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
UniProt	A0A8I3PPE3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NSS9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar