TMEM145 (transmembrane protein 145) - Rat Genome Database

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Gene: TMEM145 (transmembrane protein 145) Canis lupus familiaris
Analyze
Symbol: TMEM145
Name: transmembrane protein 145
RGD ID: 12278617
Description: INVOLVED IN G protein-coupled receptor signaling pathway (inferred); response to pheromone (inferred); ASSOCIATED WITH Carpenter Syndrome 2 (ortholog); congenital hypoplastic anemia (ortholog); craniosynostosis 1 (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,063,552 - 112,072,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,063,551 - 112,072,244 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,489,936 - 111,498,385 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,676,390 - 112,684,840 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,676,511 - 112,684,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,230,630 - 112,239,046 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,866,316 - 111,875,014 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,793,094 - 112,801,544 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TMEM145
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,063,552 - 112,072,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,063,551 - 112,072,244 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,489,936 - 111,498,385 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,676,390 - 112,684,840 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,676,511 - 112,684,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,230,630 - 112,239,046 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01111,866,316 - 111,875,014 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01112,793,094 - 112,801,544 (-)NCBIUU_Cfam_GSD_1.0
TMEM145
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381942,313,309 - 42,325,064 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1942,313,309 - 42,325,064 (+)EnsemblGRCh38hg38GRCh38
GRCh371942,817,461 - 42,829,216 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,509,317 - 47,521,054 (+)NCBINCBI36Build 36hg18NCBI36
Celera1939,618,273 - 39,630,010 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1939,247,618 - 39,259,356 (+)NCBIHuRef
CHM1_11942,819,140 - 42,830,877 (+)NCBICHM1_1
T2T-CHM13v2.01945,132,694 - 45,144,449 (+)NCBIT2T-CHM13v2.0
Tmem145
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39725,004,981 - 25,015,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl725,005,531 - 25,015,620 (+)EnsemblGRCm39 Ensembl
GRCm38725,305,500 - 25,316,196 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,306,106 - 25,316,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv37726,091,127 - 26,101,214 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36725,014,868 - 25,024,955 (+)NCBIMGSCv36mm8
Celera719,921,152 - 19,931,476 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.74NCBI
Tmem145
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8190,019,727 - 90,029,432 (+)NCBIGRCr8
mRatBN7.2180,891,888 - 80,901,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,891,927 - 80,901,611 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0182,174,379 - 82,184,075 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,174,451 - 82,184,068 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,438,538 - 83,448,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,580,829 - 80,590,503 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera175,334,816 - 75,344,483 (+)NCBICelera
Cytogenetic Map1q21NCBI
Tmem145
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555592,940 - 602,902 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955555592,685 - 602,950 (-)NCBIChiLan1.0ChiLan1.0
TMEM145
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,418,281 - 48,430,006 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11950,286,901 - 50,298,625 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01939,201,037 - 39,212,761 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,793,267 - 47,804,752 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,793,267 - 47,804,526 (+)Ensemblpanpan1.1panPan2
Tmem145
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934915,850,761 - 15,859,465 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706198,339 - 206,739 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706198,105 - 206,794 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM145
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,619,547 - 49,628,239 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,619,540 - 49,628,234 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,513,930 - 45,522,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM145
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,517,715 - 36,528,918 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,517,826 - 36,529,397 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,763,629 - 14,774,920 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem145
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907438,968 - 448,005 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907438,713 - 448,037 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM145
85 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000007792   ⟹   ENSCAFP00000007224
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1112,063,551 - 112,072,244 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000067325   ⟹   ENSCAFP00000055898
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1112,064,121 - 112,072,244 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845001352   ⟹   ENSCAFP00845001043
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1112,676,511 - 112,684,868 (-)Ensembl
RefSeq Acc Id: XM_038441132   ⟹   XP_038297060
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1111,489,936 - 111,498,363 (-)NCBI
RefSeq Acc Id: XM_038441183   ⟹   XP_038297111
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1111,489,936 - 111,498,385 (-)NCBI
RefSeq Acc Id: XM_038467989   ⟹   XP_038323917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11112,230,630 - 112,239,046 (-)NCBI
RefSeq Acc Id: XM_038528726   ⟹   XP_038384654
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,793,094 - 112,801,522 (-)NCBI
RefSeq Acc Id: XM_038528727   ⟹   XP_038384655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01112,793,094 - 112,801,544 (-)NCBI
RefSeq Acc Id: XM_038593001   ⟹   XP_038448929
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,866,316 - 111,874,992 (-)NCBI
RefSeq Acc Id: XM_038593002   ⟹   XP_038448930
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01111,866,316 - 111,875,014 (-)NCBI
RefSeq Acc Id: XM_038656815   ⟹   XP_038512743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,676,390 - 112,684,818 (-)NCBI
RefSeq Acc Id: XM_038656816   ⟹   XP_038512744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01112,676,390 - 112,684,840 (-)NCBI
Ensembl Acc Id: ENSCAFP00000055898   ⟸   ENSCAFT00000067325
Ensembl Acc Id: ENSCAFP00000007224   ⟸   ENSCAFT00000007792
RefSeq Acc Id: XP_038323917   ⟸   XM_038467989
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448930   ⟸   XM_038593002
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038448929   ⟸   XM_038593001
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038512744   ⟸   XM_038656816
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNT7 (UniProtKB/TrEMBL),   A0A8C0M972 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512743   ⟸   XM_038656815
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MH64 (UniProtKB/TrEMBL),   A0A8P0T841 (UniProtKB/TrEMBL),   A0A8C0KM65 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038297111   ⟸   XM_038441183
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNT7 (UniProtKB/TrEMBL),   A0A8C0M972 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038297060   ⟸   XM_038441132
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MH64 (UniProtKB/TrEMBL),   A0A8P0T841 (UniProtKB/TrEMBL),   A0A8C0KM65 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384655   ⟸   XM_038528727
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KNT7 (UniProtKB/TrEMBL),   A0A8C0M972 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384654   ⟸   XM_038528726
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KM65 (UniProtKB/TrEMBL),   A0A8I3MH64 (UniProtKB/TrEMBL),   A0A8P0T841 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845001043   ⟸   ENSCAFT00845001352
Protein Domains
GPR180-like N-terminal   GPR180/TMEM145 transmembrane

Promoters
RGD ID:13682272
Promoter ID:EPDNEW_C340
Type:single initiation site
Name:TMEM145_1
Description:transmembrane protein 145
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11112,072,054 - 112,072,114EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004834 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004067 UniProtKB/TrEMBL
  ENSCAFG00845000809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007792.5 UniProtKB/TrEMBL
  ENSCAFT00000067325.2 UniProtKB/TrEMBL
  ENSCAFT00030007578.1 UniProtKB/TrEMBL
  ENSCAFT00845001352 ENTREZGENE
  ENSCAFT00845001352.1 UniProtKB/TrEMBL
InterPro GPR180-like_N UniProtKB/TrEMBL
  GPR180/TMEM145 UniProtKB/TrEMBL
  Intimal_thickness-rel_rcpt UniProtKB/TrEMBL
NCBI Gene TMEM145 ENTREZGENE
PANTHER INTIMAL THICKNESS RECEPTOR-RELATED UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 145 UniProtKB/TrEMBL
Pfam GpcrRhopsn4 UniProtKB/TrEMBL
  TMEM145_N UniProtKB/TrEMBL
UniProt A0A8C0KM65 ENTREZGENE
  A0A8C0KNT7 ENTREZGENE
  A0A8C0M972 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MH64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N7J9_CANLF UniProtKB/TrEMBL
  A0A8P0T841 ENTREZGENE, UniProtKB/TrEMBL