SSR2 (signal sequence receptor subunit 2) - Rat Genome Database

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Gene: SSR2 (signal sequence receptor subunit 2) Canis lupus familiaris
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Symbol: SSR2
Name: signal sequence receptor subunit 2
RGD ID: 12274009
Description: INVOLVED IN in utero embryonic development (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glycoprotein 25H; gp25H; signal sequence receptor beta subunit; SSR-beta; translocon-associated protein subunit beta; TRAP-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,790,289 - 41,801,438 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,795,565 - 41,801,421 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,284,537 - 41,290,952 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,656,990 - 41,668,191 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,662,314 - 41,668,174 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,442,596 - 41,449,006 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,496,229 - 41,502,635 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,780,416 - 41,786,822 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1918067   PMID:2177473   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SSR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,790,289 - 41,801,438 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,795,565 - 41,801,421 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,284,537 - 41,290,952 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,656,990 - 41,668,191 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,662,314 - 41,668,174 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,442,596 - 41,449,006 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,496,229 - 41,502,635 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,780,416 - 41,786,822 (+)NCBIUU_Cfam_GSD_1.0
SSR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,009,048 - 156,020,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,009,048 - 156,020,951 (-)EnsemblGRCh38hg38GRCh38
GRCh371155,978,839 - 155,990,742 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,245,463 - 154,257,382 (-)NCBINCBI36Build 36hg18NCBI36
Build 341152,791,912 - 152,803,800NCBI
Celera1129,051,733 - 129,062,855 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,340,483 - 127,353,288 (-)NCBIHuRef
CHM1_11157,374,969 - 157,386,857 (-)NCBICHM1_1
T2T-CHM13v2.01155,147,508 - 155,159,414 (-)NCBIT2T-CHM13v2.0
Ssr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,486,915 - 88,495,727 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,483,183 - 88,495,726 (+)EnsemblGRCm39 Ensembl
GRCm38388,579,608 - 88,588,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,575,876 - 88,588,419 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,383,593 - 88,392,335 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,665,598 - 88,674,340 (+)NCBIMGSCv36mm8
Celera388,619,460 - 88,628,470 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.88NCBI
Ssr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,346,117 - 176,354,868 (+)NCBIGRCr8
mRatBN7.22174,048,291 - 174,057,043 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,048,460 - 174,057,042 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2181,194,310 - 181,202,924 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02179,216,672 - 179,225,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02173,816,822 - 173,825,548 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02187,951,316 - 187,960,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,951,344 - 187,960,063 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,354,107 - 207,362,738 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,705,121 - 180,713,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,655,227 - 180,663,976 (+)NCBI
Celera2167,992,723 - 168,001,460 (+)NCBICelera
Cytogenetic Map2q34NCBI
Ssr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,205,906 - 2,212,851 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,205,906 - 2,213,780 (-)NCBIChiLan1.0ChiLan1.0
SSR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,827,397 - 93,839,373 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,559,366 - 93,571,348 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,349,072 - 131,361,008 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,179,067 - 135,190,965 (-)NCBIpanpan1.1PanPan1.1panPan2
Ssr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,240,029 - 26,247,058 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365805,270,384 - 5,276,732 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365805,270,411 - 5,277,435 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SSR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,011,527 - 94,021,962 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,010,724 - 94,021,964 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,753,723 - 102,764,968 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SSR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,844,461 - 7,856,869 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,844,430 - 7,856,999 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,143,387 - 7,155,692 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ssr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248851,364,563 - 1,372,466 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248851,365,651 - 1,372,778 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SSR2
116 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022420733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022420734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022420735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022420736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO679178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN431908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN869892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000026734   ⟹   ENSCAFP00000024839
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl741,795,565 - 41,801,226 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000068817   ⟹   ENSCAFP00000048694
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl741,795,565 - 41,800,909 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000087015   ⟹   ENSCAFP00000066726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl741,795,565 - 41,801,421 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845018547   ⟹   ENSCAFP00845014468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl741,662,314 - 41,668,174 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845018570   ⟹   ENSCAFP00845014487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl741,662,314 - 41,667,979 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845018599   ⟹   ENSCAFP00845014510
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl741,662,314 - 41,667,662 (+)Ensembl
RefSeq Acc Id: NM_001003269   ⟹   NP_001003269
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1741,795,021 - 41,801,435 (+)NCBI
Dog10K_Boxer_Tasha741,284,537 - 41,290,952 (+)NCBI
ROS_Cfam_1.0741,661,765 - 41,668,188 (+)NCBI
UMICH_Zoey_3.1741,442,596 - 41,449,006 (+)NCBI
UNSW_CanFamBas_1.0741,496,229 - 41,502,635 (+)NCBI
UU_Cfam_GSD_1.0741,780,416 - 41,786,822 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038670488   ⟹   XP_038526416
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0741,661,701 - 41,668,191 (+)NCBI
RefSeq Acc Id: XM_038670489   ⟹   XP_038526417
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0741,657,055 - 41,668,191 (+)NCBI
RefSeq Acc Id: XM_038670490   ⟹   XP_038526418
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0741,661,943 - 41,668,191 (+)NCBI
RefSeq Acc Id: XM_038670491   ⟹   XP_038526419
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0741,656,990 - 41,668,191 (+)NCBI
RefSeq Acc Id: NP_001003269   ⟸   NM_001003269
- Peptide Label: precursor
- UniProtKB: P23438 (UniProtKB/Swiss-Prot),   A0A8C0JXR5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000048694   ⟸   ENSCAFT00000068817
Ensembl Acc Id: ENSCAFP00000066726   ⟸   ENSCAFT00000087015
Ensembl Acc Id: ENSCAFP00000024839   ⟸   ENSCAFT00000026734
RefSeq Acc Id: XP_038526419   ⟸   XM_038670491
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038526417   ⟸   XM_038670489
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038526416   ⟸   XM_038670488
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038526418   ⟸   XM_038670490
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCAFP00845014487   ⟸   ENSCAFT00845018570
Ensembl Acc Id: ENSCAFP00845014510   ⟸   ENSCAFT00845018599
Ensembl Acc Id: ENSCAFP00845014468   ⟸   ENSCAFT00845018547

Promoters
RGD ID:13684007
Promoter ID:EPDNEW_C2076
Type:initiation region
Name:SSR2_1
Description:signal sequence receptor subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1741,795,032 - 41,795,092EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016882 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00030000294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00040021358 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSCAFG00805002931 UniProtKB/Swiss-Prot
  ENSCAFG00845010530 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026734.5 UniProtKB/Swiss-Prot
  ENSCAFT00000068817.2 UniProtKB/TrEMBL
  ENSCAFT00000087015.2 UniProtKB/TrEMBL
  ENSCAFT00030000489.1 UniProtKB/TrEMBL
  ENSCAFT00030000502.1 UniProtKB/Swiss-Prot
  ENSCAFT00030000509.1 UniProtKB/TrEMBL
  ENSCAFT00040039629.1 UniProtKB/TrEMBL
  ENSCAFT00040039674.1 UniProtKB/Swiss-Prot
  ENSCAFT00040039700.1 UniProtKB/TrEMBL
  ENSCAFT00805005403 UniProtKB/Swiss-Prot
  ENSCAFT00845018547.1 UniProtKB/TrEMBL
  ENSCAFT00845018570 ENTREZGENE
  ENSCAFT00845018570.1 UniProtKB/Swiss-Prot
  ENSCAFT00845018599.1 UniProtKB/TrEMBL
InterPro TRAP_beta UniProtKB/Swiss-Prot
KEGG Report cfa:403950 UniProtKB/Swiss-Prot
NCBI Gene SSR2 ENTREZGENE
PANTHER TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TRAP_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF TRAP_beta UniProtKB/Swiss-Prot
UniProt A0A8C0JXR5 ENTREZGENE
  A0A8C0LR51_CANLF UniProtKB/TrEMBL
  A0A8C0LU65_CANLF UniProtKB/TrEMBL
  A0A8I3NAF6_CANLF UniProtKB/TrEMBL
  A0A8I3RVV4_CANLF UniProtKB/TrEMBL
  P23438 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:46838 ENTREZGENE