LOC484461 (zinc finger protein 234) - Rat Genome Database

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Gene: LOC484461 (zinc finger protein 234) Canis lupus familiaris
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Symbol: LOC484461 (Ensembl: ZNF227)
Name: zinc finger protein 234 (Ensembl:zinc finger protein 227)
RGD ID: 12253111
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH ethylmalonic encephalopathy (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,153,381 - 111,172,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,154,040 - 111,170,054 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,633,211 - 110,651,784 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,726,398 - 111,744,958 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,667,302 - 111,744,848 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11111,355,949 - 111,374,521 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,987,037 - 111,005,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,869,556 - 111,888,124 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC484461
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11111,153,381 - 111,172,097 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1111,154,040 - 111,170,054 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,633,211 - 110,651,784 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,726,398 - 111,744,958 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,667,302 - 111,744,848 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11111,355,949 - 111,374,521 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,987,037 - 111,005,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,869,556 - 111,888,124 (-)NCBIUU_Cfam_GSD_1.0
ZNF234
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,141,554 - 44,160,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,141,554 - 44,160,313 (+)EnsemblGRCh38hg38GRCh38
GRCh371944,645,707 - 44,664,466 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,337,618 - 49,354,127 (+)NCBINCBI36Build 36hg18NCBI36
Build 341949,337,617 - 49,354,114NCBI
Celera1941,449,810 - 41,468,561 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1941,077,850 - 41,096,601 (+)NCBIHuRef
CHM1_11944,647,537 - 44,666,288 (+)NCBICHM1_1
T2T-CHM13v2.01946,964,407 - 46,983,173 (+)NCBIT2T-CHM13v2.0
ZNF234
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22050,304,937 - 50,326,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11952,177,143 - 52,198,314 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,093,692 - 41,113,296 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11949,700,394 - 49,719,984 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1949,700,599 - 49,718,166 (+)Ensemblpanpan1.1panPan2
ZNF234
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1637,631,168 - 37,646,193 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607317,179,592 - 17,197,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC484461
151 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 21 5 6 5 6 6 12 8 10 6
Below cutoff 1 1 1

Sequence


RefSeq Acc Id: ENSCAFT00000048713   ⟹   ENSCAFP00000039845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1111,154,040 - 111,170,054 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013878   ⟹   ENSCAFP00845010764
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1111,667,302 - 111,743,061 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013905   ⟹   ENSCAFP00845010779
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1111,667,302 - 111,680,168 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013969   ⟹   ENSCAFP00845010826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1111,725,297 - 111,744,848 (-)Ensembl
RefSeq Acc Id: XM_014119890   ⟹   XP_013975365
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11111,153,381 - 111,172,097 (-)NCBI
Dog10K_Boxer_Tasha1110,633,211 - 110,651,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014119892   ⟹   XP_013975367
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11111,153,381 - 111,163,494 (-)NCBI
Dog10K_Boxer_Tasha1110,633,211 - 110,643,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038467942   ⟹   XP_038323870
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11111,355,949 - 111,374,521 (-)NCBI
RefSeq Acc Id: XM_038467943   ⟹   XP_038323871
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11111,355,949 - 111,366,065 (-)NCBI
RefSeq Acc Id: XM_038528660   ⟹   XP_038384588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01111,869,556 - 111,888,124 (-)NCBI
RefSeq Acc Id: XM_038528661   ⟹   XP_038384589
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01111,869,556 - 111,879,666 (-)NCBI
RefSeq Acc Id: XM_038592944   ⟹   XP_038448872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01110,987,037 - 111,005,601 (-)NCBI
RefSeq Acc Id: XM_038592945   ⟹   XP_038448873
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01110,987,037 - 110,997,142 (-)NCBI
RefSeq Acc Id: XM_038656749   ⟹   XP_038512677
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01111,726,398 - 111,744,958 (-)NCBI
RefSeq Acc Id: XM_038656750   ⟹   XP_038512678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01111,726,398 - 111,736,515 (-)NCBI
RefSeq Acc Id: XP_013975365   ⟸   XM_014119890
- Peptide Label: isoform X1
- UniProtKB: A0A8I3N419 (UniProtKB/TrEMBL),   A0A8P0STZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013975367   ⟸   XM_014119892
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LXS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000039845   ⟸   ENSCAFT00000048713
RefSeq Acc Id: XP_038323870   ⟸   XM_038467942
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038323871   ⟸   XM_038467943
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038448872   ⟸   XM_038592944
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448873   ⟸   XM_038592945
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038512677   ⟸   XM_038656749
- Peptide Label: isoform X1
- UniProtKB: A0A8I3N419 (UniProtKB/TrEMBL),   A0A8P0STZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038512678   ⟸   XM_038656750
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LXS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038384588   ⟸   XM_038528660
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038384589   ⟸   XM_038528661
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LXS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845010764   ⟸   ENSCAFT00845013878
RefSeq Acc Id: ENSCAFP00845010779   ⟸   ENSCAFT00845013905
RefSeq Acc Id: ENSCAFP00845010826   ⟸   ENSCAFT00845013969
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023881 UniProtKB/TrEMBL
  ENSCAFG00000030057 Ensembl
  ENSCAFG00030001155 UniProtKB/TrEMBL
  ENSCAFG00845007887 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000048713.3 UniProtKB/TrEMBL
  ENSCAFT00030001992.1 UniProtKB/TrEMBL
  ENSCAFT00845013878.1 UniProtKB/TrEMBL
  ENSCAFT00845013969 ENTREZGENE
  ENSCAFT00845013969.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report cfa:484461 UniProtKB/TrEMBL
NCBI Gene LOC484461 ENTREZGENE
PANTHER GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED UniProtKB/TrEMBL
  GENE 10130-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 239 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZIC AND GLI UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0LXS9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MWE8_CANLF UniProtKB/TrEMBL
  A0A8I3N419 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0STZ2 ENTREZGENE, UniProtKB/TrEMBL