RASL10B (RAS like family 10 member B) - Rat Genome Database

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Gene: RASL10B (RAS like family 10 member B) Canis lupus familiaris
Analyze
Symbol: RASL10B
Name: RAS like family 10 member B
RGD ID: 12213985
Description: ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN positive regulation of peptide hormone secretion (ortholog); regulation of systemic arterial blood pressure by atrial natriuretic peptide (ortholog); ASSOCIATED WITH polycystic ovary syndrome (ortholog); uterine corpus endometrial carcinoma (ortholog); FOUND IN endomembrane system (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-like protein family member 10B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,926,974 - 37,938,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,928,512 - 37,936,475 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha937,151,062 - 37,162,847 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0938,738,559 - 38,750,334 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl938,741,099 - 38,747,318 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,521,405 - 37,533,177 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0937,806,839 - 37,818,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0937,894,396 - 37,906,169 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RASL10B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,926,974 - 37,938,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,928,512 - 37,936,475 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha937,151,062 - 37,162,847 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0938,738,559 - 38,750,334 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl938,741,099 - 38,747,318 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,521,405 - 37,533,177 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0937,806,839 - 37,818,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0937,894,396 - 37,906,169 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
RASL10B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381735,731,639 - 35,743,521 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1735,731,639 - 35,743,521 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371734,058,658 - 34,070,540 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361731,082,871 - 31,094,653 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341731,082,870 - 31,094,652NCBI
Celera1730,968,817 - 30,980,678 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1730,243,842 - 30,255,703 (+)NCBIHuRef
CHM1_11734,123,293 - 34,135,075 (+)NCBICHM1_1
T2T-CHM13v2.01736,679,576 - 36,691,458 (+)NCBIT2T-CHM13v2.0
Rasl10b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,299,963 - 83,311,865 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1183,299,788 - 83,316,342 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381183,409,137 - 83,421,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,409,137 - 83,421,039 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371183,223,574 - 83,234,540 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361183,226,267 - 83,237,233 (+)NCBIMGSCv36mm8
Celera1193,004,681 - 93,015,598 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
Rasl10b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,707,315 - 68,719,642 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1068,707,359 - 68,719,641 (+)EnsemblGRCr8
mRatBN7.21068,209,761 - 68,222,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1068,210,275 - 68,220,376 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1072,830,464 - 72,840,389 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01072,335,847 - 72,345,772 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,799,897 - 67,809,826 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1071,579,826 - 71,589,745 (+)NCBI
Lyon_Normotensive1072,301,289 - 72,311,212 (+)NCBI
Lyon_Hypertensive1073,975,378 - 73,985,301 (+)NCBI
F344_StmMcwi1073,863,907 - 73,873,828 (+)NCBI
Rnor_6.01070,626,227 - 70,639,072 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,627,401 - 70,637,332 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01071,088,792 - 71,101,096 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41071,492,903 - 71,503,357 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1067,154,665 - 67,161,892 (+)NCBICelera
RGSC_v3.11071,506,045 - 71,517,512 (+)NCBI
Cytogenetic Map10q26NCBI
Rasl10b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495548110,180,009 - 10,192,155 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495548110,183,635 - 10,192,155 (+)NCBIChiLan1.0ChiLan1.0
RASL10B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21928,733,852 - 28,745,748 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11730,613,089 - 30,624,978 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,052,147 - 21,064,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,346,472 - 21,355,788 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,346,472 - 21,355,788 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Rasl10b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1336,944,614 - 36,956,853 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_02440560236,929,571 - 36,941,851 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936490133,950 - 145,476 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936490134,105 - 145,479 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASL10B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,783,729 - 39,795,069 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11239,783,725 - 39,795,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RASL10B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap11634,026,905 - 34,039,503 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_023666075756,265 - 768,553 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.11629,206,835 - 29,219,420 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1629,210,786 - 29,219,408 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Rasl10b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248753,217,577 - 3,225,627 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248753,214,793 - 3,225,597 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Rasl10b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1987,262,182 - 87,274,486 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in RASL10B
160 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000028901   ⟹   ENSCAFP00000026879
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl937,928,512 - 37,936,475 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845016887   ⟹   ENSCAFP00845013140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl938,741,099 - 38,747,318 (-)Ensembl
RefSeq Acc Id: XM_038486268   ⟹   XP_038342196
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1937,521,405 - 37,533,177 (-)NCBI
RefSeq Acc Id: XM_038548090   ⟹   XP_038404018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0937,894,396 - 37,906,169 (-)NCBI
RefSeq Acc Id: XM_038609365   ⟹   XP_038465293
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha937,151,062 - 37,162,847 (-)NCBI
RefSeq Acc Id: XM_038612060   ⟹   XP_038467988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0937,806,839 - 37,818,619 (-)NCBI
RefSeq Acc Id: XM_038677308   ⟹   XP_038533236
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0938,738,559 - 38,750,334 (-)NCBI
Ensembl Acc Id: ENSCAFP00000026879   ⟸   ENSCAFT00000028901
RefSeq Acc Id: XP_038342196   ⟸   XM_038486268
RefSeq Acc Id: XP_038467988   ⟸   XM_038612060
RefSeq Acc Id: XP_038533236   ⟸   XM_038677308
- UniProtKB: A0A8C0JS30 (UniProtKB/TrEMBL),   A0A8I3N2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038465293   ⟸   XM_038609365
- UniProtKB: A0A8C0JS30 (UniProtKB/TrEMBL),   A0A8I3N2V7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404018   ⟸   XM_038548090
- UniProtKB: A0A8C0JS30 (UniProtKB/TrEMBL),   A0A8I3N2V7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845013140   ⟸   ENSCAFT00845016887

Promoters
RGD ID:13684647
Promoter ID:EPDNEW_C2715
Type:single initiation site
Name:RASL10B_1
Description:RAS like family 10 member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1937,935,788 - 37,935,848EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018193 Ensembl
  ENSCAFG00845009585 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845016887 ENTREZGENE
  ENSCAFT00845016887.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Ras-like_GTPase_Reg UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report cfa:491138 UniProtKB/TrEMBL
NCBI Gene RASL10B ENTREZGENE
PANTHER RAS LIKE FAMILY 10 MEMBER B-RELATED UniProtKB/TrEMBL
  RAS-LIKE PROTEIN FAMILY MEMBER 10B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0JS30 ENTREZGENE
  A0A8I3N2V7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45376 ENTREZGENE