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Gene: IRX2 (iroquois homeobox 2) Canis lupus familiaris

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Symbol:

IRX2

Name:

iroquois homeobox 2

RGD ID:

12195904

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN metanephros development (inferred); negative regulation of transcription by RNA polymerase II (inferred); proximal/distal pattern formation involved in metanephric nephron development (inferred); ASSOCIATED WITH lung disease (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

iroquois homeobox protein 2; iroquois-class homeodomain protein IRX-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IRX2 (iroquois homeobox 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Irx2 (Iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Irx2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Irx2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IRX2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Irx2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IRX2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IRX2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Irx2 (iroquois homeobox 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	10,228,067 - 10,233,214 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	10,227,807 - 10,232,998 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	14,739,959 - 14,745,015 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	10,129,223 - 10,134,284 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	10,128,924 - 10,134,068 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	10,182,769 - 10,187,824 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	10,154,470 - 10,159,509 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	10,371,265 - 10,376,323 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

lung disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell development (IBA)

metanephros development (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

neuron differentiation (IBA)

proximal/distal pattern formation involved in metanephric nephron development (IEA)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA,IEA)

specification of loop of Henle identity (IEA)

Cellular Component

nucleus (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

IRX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	10,228,067 - 10,233,214 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	10,227,807 - 10,232,998 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	14,739,959 - 14,745,015 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	10,129,223 - 10,134,284 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	10,128,924 - 10,134,068 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	10,182,769 - 10,187,824 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	10,154,470 - 10,159,509 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	10,371,265 - 10,376,323 (+)	NCBI		UU_Cfam_GSD_1.0

IRX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	2,735,635 - 2,751,677 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	2,745,845 - 2,751,677 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	2,745,959 - 2,751,791 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	2,799,880 - 2,804,769 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	2,799,879 - 2,804,769	NCBI
Celera	5	2,778,127 - 2,783,618 (-)	NCBI		Celera
Cytogenetic Map	5	p15.33	NCBI
HuRef	5	2,722,301 - 2,727,305 (-)	NCBI		HuRef
CHM1_1	5	2,746,153 - 2,751,637 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	2,651,419 - 2,666,690 (-)	NCBI		T2T-CHM13v2.0

Irx2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	72,771,463 - 72,782,315 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	72,776,939 - 72,782,317 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	72,624,430 - 72,634,196 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	72,628,820 - 72,634,198 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	72,766,426 - 72,771,642 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	73,095,476 - 73,100,582 (+)	NCBI		MGSCv36	mm8
Celera	13	74,957,966 - 74,961,598 (+)	NCBI		Celera
Celera	16	30,904,806 - 30,905,142 (-)	NCBI		Celera
Cytogenetic Map	13	C1	NCBI
cM Map	13	39.23	NCBI

Irx2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	32,489,512 - 32,494,930 (-)	NCBI		GRCr8
mRatBN7.2	1	30,660,960 - 30,666,378 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	30,660,960 - 30,666,378 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	30,463,094 - 30,468,512 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	36,462,033 - 36,467,451 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	30,661,873 - 30,667,293 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	33,270,388 - 33,275,868 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	33,271,977 - 33,275,540 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	34,682,802 - 34,688,217 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	743,534 - 748,950 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	743,533 - 748,952 (-)	NCBI
Celera	1	29,295,635 - 29,301,053 (-)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

Irx2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955504	1,455,664 - 1,460,996 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955504	1,456,433 - 1,460,996 (-)	NCBI	ChiLan1.0	ChiLan1.0

IRX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	3,006,268 - 3,011,777 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	1,160,101 - 1,165,376 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	3,081,361 - 3,087,014 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	2,776,054 - 2,777,005 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

Irx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	243,239,343 - 243,243,455 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936634	3,829,663 - 3,834,806 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936634	3,830,617 - 3,834,494 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IRX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	78,305,793 - 78,309,786 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	78,305,869 - 78,322,776 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	84,598,270 - 84,601,553 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IRX2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	2,547,205 - 2,552,085 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	2,546,280 - 2,550,252 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666064	26,269,348 - 26,275,139 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Irx2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	1,453,390 - 1,457,470 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	1,453,390 - 1,457,500 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in IRX2
61 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038445529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038519707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038583349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038647764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_843487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000016569 ⟹ ENSCAFP00000015332

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	34	10,227,807 - 10,232,998 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043871 ⟹ ENSCAFP00845034381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	34	10,128,924 - 10,134,068 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043919 ⟹ ENSCAFP00845034416

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	34	10,128,924 - 10,134,068 (+)	Ensembl

RefSeq Acc Id:

XM_038445529 ⟹ XP_038301457

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	34	10,129,223 - 10,134,284 (+)	NCBI

RefSeq Acc Id:

XM_038519707 ⟹ XP_038375635

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	34	10,182,769 - 10,187,824 (+)	NCBI

RefSeq Acc Id:

XM_038583349 ⟹ XP_038439277

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	34	10,371,265 - 10,376,323 (+)	NCBI

RefSeq Acc Id:

XM_038647764 ⟹ XP_038503692

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	34	10,154,470 - 10,159,509 (+)	NCBI

RefSeq Acc Id:

XM_843487 ⟹ XP_848580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	34	10,228,067 - 10,233,214 (+)	NCBI
Dog10K_Boxer_Tasha	34	14,739,959 - 14,745,015 (+)	NCBI

Sequence:

show sequence

GCCGCGCCGCGCCCCGGCCGGGCGTGGATGGAGGGCGCCGCGCGCCTGGCCGGCTGCTCGGCGT
GAGGCGGGCCCCGCGCCCCGCGCCCACCATGTCCTACCCGCAGGGCTACCTGTACCAGGCGCCC
GGCTCGCTGGCGCTCTACTCGTGCCCGGCGTACGGCGCCTCGGCGCTGGCGGCGCCGCGCAGCG
AGGAGCTGGCTCGCTCGGCGTCGGGCTCGGCGTTCAGCCCGTACCCGGGCTCCGCGGCCTTCAC
GGCACAGGCGGCCACCGGCTTCGGCAGCCCGCTGCAGTACTCGGCCGACGCCGCCGCCGCCGCC
GGCTTCCCGTCCTACATGGGCGCGCCCTACGACGCCCATACGACCGGGATGACGGGCGCCATCA
GCTACCACCCGTACGGCAGCGCGGCCTACCCGTACCAGCTCAACGACCCCGCGTACCGCAAGAA
CGCCACGCGGGACGCCACGGCCACGCTCAAGGCCTGGCTCAACGAGCACCGCAAGAACCCCTAC
CCCACCAAGGGCGAGAAGATCATGCTGGCCATCATCACCAAGATGACCCTCACGCAGGTGTCCA
CCTGGTTCGCCAACGCGCGCCGGCGTCTCAAGAAGGAGAACAAGATGACATGGGCGCCCAGGAA
CAAAAGCGAGGACGAGGACGAGGACGAGGGCGACGCCGCCAGGAGCAAGGGAGAGAGCCCAGAC
AAGGCGCAGGAGGGCACCGAGACGTCAGCGGAGGACGAAGGGATCAGCCTGCACGTCGACTCGC
TCACGGATCACTCGTGCTCCGCCGAGTCGGACGGGGAGAAGCTGCCGTGTCGGCCCGGGGACCC
CCTGTGCGAGTCGGGCTCCGAGTGCAAGGACAAATACGACGACCTGGAGGACGACGAGGACGAC
GACGAGGAGGGCGAGCGGGACCTGGCGCCGCCCAAGCCCGTGACCTCGTCGCCGCTCACCGGCG
TGGAGGCGCCGCTGCTGAGCCCCCCGCCCGAGGCCGCGCCCCGCGGCGGCGGCGGCGGCAAGAT
GCCCCTGGGCAGCCGGACGTCGCCGGGCGCGCCGCAGCCCGCCAGCAAGCCCAAGCTGTGGTCT
CTGGCCGAGATCGCCACGTCGGACCTCAAGCAGCCGAGCCTGGGCCCGGGCTGCGCACCGCCGG
GGCTGCCCGCGGCCGCCGCGCCCGCCTCCTCCGGGGCGCCGCCGGGCGGCTCGCCCTACCCCGC
GTCGCCGCTGCTCGGCCGCCACCTGTACTACACATCGCCCTTCTACGGCAACTATACAAACTAC
GGGAACTTGAACGCGGCGCTGCAGGGCCAGGGGCTCCTGCGCTACAACTCGGCGGCCGCGGCCC
CCGGAGAGGCGCTGCACTCCGCGCCCAAGGCGGCCAGCGACGCGGGCAAGGCGGGCGCGCACCC
GCTGGAGCCGCACTACCGGCCTCCGGGCGGCGGCTACGAGCCCAAGAAAGATGCCAGTGAGGGC
TGCACCGTGGTTGGTGGGGGCGTCCAGCCCTACCTATAGAAGGCCCCGCGCGCACAGCAATGCA
AGTAGGTGTCACAATTGCTTTGGAAAAAAAAAAAGTCAGCAGGCCATTCTCTCTCCCCAAGTTC
AGAAATACACAGATATAAAAAAACACATCTCTAAGCCCGGACCGCATCTCGTGCCACTATAAAG
GAGAAGGCGCCACAGACTCTATCGGAACAGACTTTTATTGGACATGACGTGAATTTGTTGGCAT
AGTATAGCTTCCCCAACGTATGTGTGACTTTTGAAAACAATCTTTTTTCTCAGGATATCTTGAA
TTGATCACTTCATTGCCACGGTATATATTCTCTAGGTGTGATAGGACTTACTGTAAAATTTATT
TGTAAAAGATGTACACAGTAGAAATAAAATGTGATTGAGAAACTTGAGTACTTAAGAAGTGGAA
ACAAATTTGATATTTATTTTTATAATGATATAAAGCTTCTAGTAATTTATGCAAGTTGTATTGC
AATGGAATCTAAACTTTTTGTAAATAAATTCTGCCTGGTTTTTATTTGAACATTGCTGGTTATA
CAATCTTTGTTGGTTGTTTAACAAGAATTCTTTACTAATTTATATCTTAAATTGTAAATAAAAA
CAGACTAGTCTACGACAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038301457	(Get FASTA)	NCBI Sequence Viewer
	XP_038375635	(Get FASTA)	NCBI Sequence Viewer
	XP_038439277	(Get FASTA)	NCBI Sequence Viewer
	XP_038503692	(Get FASTA)	NCBI Sequence Viewer
	XP_848580	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000015332.4
	ENSCAFP00000070143.1
	ENSCAFP00030016078.1
	ENSCAFP00040039568.1
	ENSCAFP00845034381.1
	ENSCAFP00845034416
	ENSCAFP00845034416.1

RefSeq Acc Id:

XP_848580 ⟸ XM_843487

- UniProtKB:

A0A8C0LBQ7 (UniProtKB/TrEMBL), A0A8C0N5G3 (UniProtKB/TrEMBL), A0A8I3PP48 (UniProtKB/TrEMBL), A0A8I3S8Y4 (UniProtKB/TrEMBL), A0A8P0TMN8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSYPQGYLYQAPGSLALYSCPAYGASALAAPRSEELARSASGSAFSPYPGSAAFTAQAATGFGS
PLQYSADAAAAAGFPSYMGAPYDAHTTGMTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATL
KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDE
GDAARSKGESPDKAQEGTETSAEDEGISLHVDSLTDHSCSAESDGEKLPCRPGDPLCESGSECK
DKYDDLEDDEDDDEEGERDLAPPKPVTSSPLTGVEAPLLSPPPEAAPRGGGGGKMPLGSRTSPG
APQPASKPKLWSLAEIATSDLKQPSLGPGCAPPGLPAAAAPASSGAPPGGSPYPASPLLGRHLY
YTSPFYGNYTNYGNLNAALQGQGLLRYNSAAAAPGEALHSAPKAASDAGKAGAHPLEPHYRPPG
GGYEPKKDASEGCTVVGGGVQPYL

hide sequence

Ensembl Acc Id:

ENSCAFP00000015332 ⟸ ENSCAFT00000016569

RefSeq Acc Id:

XP_038375635 ⟸ XM_038519707

RefSeq Acc Id:

XP_038503692 ⟸ XM_038647764

RefSeq Acc Id:	XP_038301457 ⟸ XM_038445529
- UniProtKB:	A0A8C0LBQ7 (UniProtKB/TrEMBL), A0A8C0N5G3 (UniProtKB/TrEMBL), A0A8I3PP48 (UniProtKB/TrEMBL), A0A8I3S8Y4 (UniProtKB/TrEMBL), A0A8P0TMN8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038439277 ⟸ XM_038583349
- UniProtKB:	A0A8C0Z665 (UniProtKB/TrEMBL), A0A8I3S8Y4 (UniProtKB/TrEMBL), A0A8P0TMN8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845034416 ⟸ ENSCAFT00845043919

Ensembl Acc Id:

ENSCAFP00845034381 ⟸ ENSCAFT00845043871

Protein Domains

Homeobox

Promoters

RGD ID:

13688865

Promoter ID:

EPDNEW_C6933

Type:

initiation region

Name:

IRX2_1

Description:

iroquois homeobox 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	34	10,227,936 - 10,227,996	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000010427	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009949	UniProtKB/TrEMBL
	ENSCAFG00040024321	UniProtKB/TrEMBL
	ENSCAFG00845024864	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000016569.6	UniProtKB/TrEMBL
	ENSCAFT00000104233.1	UniProtKB/TrEMBL
	ENSCAFT00030018415.1	UniProtKB/TrEMBL
	ENSCAFT00040045310.1	UniProtKB/TrEMBL
	ENSCAFT00845043871.1	UniProtKB/TrEMBL
	ENSCAFT00845043919	ENTREZGENE
	ENSCAFT00845043919.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_KN_domain	UniProtKB/TrEMBL
	Iroquois_homeo	UniProtKB/TrEMBL
KEGG Report	cfa:488064	UniProtKB/TrEMBL
NCBI Gene	IRX2	ENTREZGENE
PANTHER	IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX	UniProtKB/TrEMBL
	IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2	UniProtKB/TrEMBL
Pfam	Homeobox_KN	UniProtKB/TrEMBL
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
	IRO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A8C0LBQ7	ENTREZGENE
	A0A8C0N5G3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z665	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PP48	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S8Y4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TMN8	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:42101	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD