NPFFR1 (neuropeptide FF receptor 1) - Rat Genome Database

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Gene: NPFFR1 (neuropeptide FF receptor 1) Canis lupus familiaris
Analyze
Symbol: NPFFR1
Name: neuropeptide FF receptor 1
RGD ID: 12190804
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); neuropeptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); neuropeptide signaling pathway (inferred); FOUND IN cilium (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,191,403 - 21,223,715 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,197,733 - 21,203,099 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,323,904 - 21,351,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0421,466,975 - 21,492,765 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl421,473,411 - 21,493,131 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1421,364,430 - 21,390,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0421,569,576 - 21,595,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0421,920,758 - 21,946,551 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cilium  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NPFFR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,191,403 - 21,223,715 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,197,733 - 21,203,099 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,323,904 - 21,351,213 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0421,466,975 - 21,492,765 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl421,473,411 - 21,493,131 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1421,364,430 - 21,390,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0421,569,576 - 21,595,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0421,920,758 - 21,946,551 (-)NCBIUU_Cfam_GSD_1.0
NPFFR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381070,247,329 - 70,284,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1070,247,329 - 70,284,004 (-)EnsemblGRCh38hg38GRCh38
GRCh371072,007,085 - 72,043,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361071,684,719 - 71,707,727 (-)NCBINCBI36Build 36hg18NCBI36
Build 341071,684,718 - 71,696,154NCBI
Celera1065,294,771 - 65,323,520 (-)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1066,007,982 - 66,036,738 (-)NCBIHuRef
CHM1_11072,296,529 - 72,325,723 (-)NCBICHM1_1
T2T-CHM13v2.01071,116,278 - 71,152,972 (-)NCBIT2T-CHM13v2.0
Npffr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391061,430,600 - 61,465,243 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1061,431,271 - 61,464,344 (+)EnsemblGRCm39 Ensembl
GRCm381061,595,295 - 61,629,464 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,595,492 - 61,628,565 (+)EnsemblGRCm38mm10GRCm38
MGSCv371061,058,232 - 61,089,133 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361060,991,514 - 61,021,742 (+)NCBIMGSCv36mm8
Celera1062,696,844 - 62,727,819 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.24NCBI
Npffr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82030,082,604 - 30,116,752 (+)NCBIGRCr8
mRatBN7.22029,539,795 - 29,573,951 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2029,539,795 - 29,571,196 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2030,555,746 - 30,587,142 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02029,942,024 - 29,973,412 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02030,684,511 - 30,715,898 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02031,214,950 - 31,248,710 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2031,234,493 - 31,245,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,997,426 - 33,030,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,983,735 - 28,995,194 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12028,997,534 - 29,008,994 (+)NCBI
Celera2030,966,998 - 30,998,217 (+)NCBICelera
Cytogenetic Map20q11NCBI
Npffr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,976,867 - 21,001,194 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,976,867 - 21,001,194 (+)NCBIChiLan1.0ChiLan1.0
NPFFR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2882,401,334 - 82,438,138 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11082,406,655 - 82,443,459 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01066,721,483 - 66,758,287 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11069,257,022 - 69,291,838 (-)NCBIpanpan1.1PanPan1.1panPan2
Npffr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,834,368 - 59,851,935 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365218,329,153 - 8,342,246 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365218,327,093 - 8,342,390 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPFFR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,182,892 - 73,205,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,183,585 - 73,195,804 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,103,900 - 79,116,127 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPFFR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1961,030,574 - 61,052,052 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl961,041,567 - 61,051,960 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604821,770,185 - 21,792,342 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Npffr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247544,396,759 - 4,406,078 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247544,390,049 - 4,410,208 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NPFFR1
429 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 4 1 23 16 10 1 5 1 6 19 14 12 14 9

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038473153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038486534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038598524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_846842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000022287   ⟹   ENSCAFP00000020700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl421,197,733 - 21,203,099 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845007560   ⟹   ENSCAFP00845005971
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl421,473,411 - 21,493,131 (-)Ensembl
RefSeq Acc Id: XM_038473153   ⟹   XP_038329081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1421,364,430 - 21,390,200 (-)NCBI
RefSeq Acc Id: XM_038486534   ⟹   XP_038342462
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha421,323,904 - 21,351,213 (-)NCBI
RefSeq Acc Id: XM_038534202   ⟹   XP_038390130
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,925,839 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534203   ⟹   XP_038390131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,920,758 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534204   ⟹   XP_038390132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,924,332 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534205   ⟹   XP_038390133
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,925,840 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534206   ⟹   XP_038390134
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,925,839 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534207   ⟹   XP_038390135
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,924,310 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534209   ⟹   XP_038390137
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,920,758 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038534210   ⟹   XP_038390138
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0421,920,758 - 21,946,551 (-)NCBI
RefSeq Acc Id: XM_038598516   ⟹   XP_038454444
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,574,648 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598517   ⟹   XP_038454445
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,569,576 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598518   ⟹   XP_038454446
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,573,150 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598519   ⟹   XP_038454447
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,574,649 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598520   ⟹   XP_038454448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,574,648 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598522   ⟹   XP_038454450
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,573,128 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598523   ⟹   XP_038454451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,569,576 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038598524   ⟹   XP_038454452
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0421,569,576 - 21,595,343 (-)NCBI
RefSeq Acc Id: XM_038662819   ⟹   XP_038518747
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0421,466,975 - 21,492,765 (-)NCBI
Ensembl Acc Id: ENSCAFP00000020700   ⟸   ENSCAFT00000022287
RefSeq Acc Id: XP_038329081   ⟸   XM_038473153
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454445   ⟸   XM_038598517
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454452   ⟸   XM_038598524
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038454451   ⟸   XM_038598523
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038454450   ⟸   XM_038598522
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454446   ⟸   XM_038598518
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454448   ⟸   XM_038598520
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454444   ⟸   XM_038598516
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454447   ⟸   XM_038598519
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038518747   ⟸   XM_038662819
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038342462   ⟸   XM_038486534
- Peptide Label: isoform X6
- UniProtKB: A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390131   ⟸   XM_038534203
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390138   ⟸   XM_038534210
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038390137   ⟸   XM_038534209
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038390135   ⟸   XM_038534207
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390132   ⟸   XM_038534204
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390134   ⟸   XM_038534206
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390130   ⟸   XM_038534202
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390133   ⟸   XM_038534205
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NC84 (UniProtKB/TrEMBL),   A0A8P0SIU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845005971   ⟸   ENSCAFT00845007560
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014038 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013923 UniProtKB/TrEMBL
  ENSCAFG00845004215 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000022287.5 UniProtKB/TrEMBL
  ENSCAFT00030025776.1 UniProtKB/TrEMBL
  ENSCAFT00845007560 ENTREZGENE
  ENSCAFT00845007560.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  NPFF_rcpt UniProtKB/TrEMBL
  NPFF_rcpt_1 UniProtKB/TrEMBL
NCBI Gene NPFFR1 ENTREZGENE
PANTHER NEUROPEPTIDE FF RECEPTOR 1 UniProtKB/TrEMBL
  NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  NPFFRECEPTOR UniProtKB/TrEMBL
  NPFFRECEPTR1 UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0NC84 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MPF9_CANLF UniProtKB/TrEMBL
  A0A8P0SIU0 ENTREZGENE, UniProtKB/TrEMBL