RIPPLY3 (ripply transcriptional repressor 3) - Rat Genome Database

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Gene: RIPPLY3 (ripply transcriptional repressor 3) Canis lupus familiaris
Analyze
Symbol: RIPPLY3
Name: ripply transcriptional repressor 3
RGD ID: 12182513
Description: INVOLVED IN cell population proliferation (ortholog); heart development (ortholog); negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); epilepsy (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Down syndrome critical region gene 6; DSCR6; protein ripply3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13132,150,768 - 32,188,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3132,150,882 - 32,188,436 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3131,239,163 - 31,249,248 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03131,481,096 - 31,491,184 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3131,481,116 - 31,506,328 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13131,349,063 - 31,359,184 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03131,362,083 - 31,372,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,852,602 - 31,862,690 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RIPPLY3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13132,150,768 - 32,188,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3132,150,882 - 32,188,436 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3131,239,163 - 31,249,248 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03131,481,096 - 31,491,184 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3131,481,116 - 31,506,328 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13131,349,063 - 31,359,184 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03131,362,083 - 31,372,228 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,852,602 - 31,862,690 (+)NCBIUU_Cfam_GSD_1.0
RIPPLY3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382137,006,150 - 37,019,662 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2137,006,150 - 37,019,662 (+)EnsemblGRCh38hg38GRCh38
GRCh372138,378,450 - 38,391,962 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362137,300,733 - 37,313,829 (+)NCBINCBI36Build 36hg18NCBI36
Build 342137,300,732 - 37,313,826NCBI
Celera2123,577,251 - 23,590,347 (+)NCBICelera
Cytogenetic Map21q22.13NCBI
HuRef2123,854,553 - 23,867,647 (+)NCBIHuRef
CHM1_12137,940,236 - 37,953,313 (+)NCBICHM1_1
T2T-CHM13v2.02135,388,362 - 35,401,872 (+)NCBIT2T-CHM13v2.0
Ripply3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391694,129,281 - 94,137,794 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1694,129,279 - 94,137,794 (+)EnsemblGRCm39 Ensembl
GRCm381694,328,422 - 94,336,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1694,328,420 - 94,336,935 (+)EnsemblGRCm38mm10GRCm38
MGSCv371694,550,029 - 94,558,542 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361694,437,218 - 94,445,733 (+)NCBIMGSCv36mm8
Celera1695,415,747 - 95,424,097 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1655.17NCBI
Ripply3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81147,118,147 - 47,126,244 (+)NCBIGRCr8
mRatBN7.21133,648,471 - 33,656,587 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,648,486 - 33,656,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1142,303,306 - 42,311,405 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01134,974,670 - 34,982,769 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01134,123,066 - 34,131,163 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,557,679 - 34,565,776 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,557,679 - 34,565,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,145,428 - 38,153,525 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,575,083 - 34,583,180 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11134,631,403 - 34,639,055 (+)NCBI
Celera1134,793,208 - 34,801,305 (-)NCBICelera
Cytogenetic Map11q11NCBI
Ripply3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540736,101,206 - 36,108,808 (+)NCBIChiLan1.0ChiLan1.0
RIPPLY3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22233,118,522 - 33,130,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12127,979,071 - 27,991,153 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02123,368,472 - 23,379,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12136,723,931 - 36,734,886 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2136,723,931 - 36,734,382 (+)Ensemblpanpan1.1panPan2
RIPPLY3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113200,642,802 - 200,652,401 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213210,717,930 - 210,727,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RIPPLY3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1280,992,876 - 81,001,956 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660548,835,299 - 8,847,263 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ripply3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474526,636,307 - 26,658,373 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RIPPLY3
628 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000015396   ⟹   ENSCAFP00000014247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3132,150,882 - 32,188,436 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845049126   ⟹   ENSCAFP00845038544
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3131,481,116 - 31,506,328 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845049159   ⟹   ENSCAFP00845038572
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3131,481,116 - 31,490,858 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845049198   ⟹   ENSCAFP00845038606
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3131,481,116 - 31,490,376 (+)Ensembl
RefSeq Acc Id: XM_038443479   ⟹   XP_038299407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03131,481,096 - 31,491,184 (+)NCBI
RefSeq Acc Id: XM_038443480   ⟹   XP_038299408
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03131,481,096 - 31,491,184 (+)NCBI
RefSeq Acc Id: XM_038461666   ⟹   XP_038317594
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3131,239,163 - 31,249,248 (+)NCBI
RefSeq Acc Id: XM_038517893   ⟹   XP_038373821
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13131,349,063 - 31,359,184 (+)NCBI
RefSeq Acc Id: XM_038581466   ⟹   XP_038437394
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03131,852,602 - 31,862,690 (+)NCBI
RefSeq Acc Id: XM_038581467   ⟹   XP_038437395
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03131,852,602 - 31,862,690 (+)NCBI
RefSeq Acc Id: XM_038645842   ⟹   XP_038501770
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03131,362,083 - 31,372,228 (+)NCBI
Ensembl Acc Id: ENSCAFP00000014247   ⟸   ENSCAFT00000015396
RefSeq Acc Id: XP_038373821   ⟸   XM_038517893
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038501770   ⟸   XM_038645842
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038299408   ⟸   XM_038443480
- Peptide Label: isoform X1
- UniProtKB: A0A8I3Q7A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038299407   ⟸   XM_038443479
- Peptide Label: isoform X2
- UniProtKB: A0A8I3Q7A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038317594   ⟸   XM_038461666
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LF30 (UniProtKB/TrEMBL),   A0A8C0T937 (UniProtKB/TrEMBL),   A0A8P0TV77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038437395   ⟸   XM_038581467
- Peptide Label: isoform X1
- UniProtKB: A0A8I3Q7A3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038437394   ⟸   XM_038581466
- Peptide Label: isoform X2
- UniProtKB: A0A8I3Q7A3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038544   ⟸   ENSCAFT00845049126
Ensembl Acc Id: ENSCAFP00845038572   ⟸   ENSCAFT00845049159
Ensembl Acc Id: ENSCAFP00845038606   ⟸   ENSCAFT00845049198


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009694 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040020433 UniProtKB/TrEMBL
  ENSCAFG00845027840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000015396.4 UniProtKB/TrEMBL
  ENSCAFT00000101597.1 UniProtKB/TrEMBL
  ENSCAFT00000108465.1 UniProtKB/TrEMBL
  ENSCAFT00000109871.1 UniProtKB/TrEMBL
  ENSCAFT00040037792.1 UniProtKB/TrEMBL
  ENSCAFT00040037805.1 UniProtKB/TrEMBL
  ENSCAFT00845049126.1 UniProtKB/TrEMBL
  ENSCAFT00845049159 ENTREZGENE
  ENSCAFT00845049159.1 UniProtKB/TrEMBL
  ENSCAFT00845049198.1 UniProtKB/TrEMBL
InterPro Ripply_fam UniProtKB/TrEMBL
NCBI Gene RIPPLY3 ENTREZGENE
PANTHER PROTEIN RIPPLY3 UniProtKB/TrEMBL
  PTHR16770 UniProtKB/TrEMBL
Pfam Ripply UniProtKB/TrEMBL
UniProt A0A8C0LF30 ENTREZGENE
  A0A8C0T937 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TD78_CANLF UniProtKB/TrEMBL
  A0A8I3PUN4_CANLF UniProtKB/TrEMBL
  A0A8I3Q2V4_CANLF UniProtKB/TrEMBL
  A0A8I3Q7A3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TQC4_CANLF UniProtKB/TrEMBL
  A0A8P0TTS5_CANLF UniProtKB/TrEMBL
  A0A8P0TV77 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0SEP3 UniProtKB/TrEMBL
VGNC ID VGNC:53037 ENTREZGENE