DNAH10 (dynein axonemal heavy chain 10) - Rat Genome Database

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Gene: DNAH10 (dynein axonemal heavy chain 10) Pan paniscus
Analyze
Symbol: DNAH10
Name: dynein axonemal heavy chain 10
RGD ID: 12037804
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); dynein intermediate chain binding (inferred); INVOLVED IN microtubule-based movement (inferred); ASSOCIATED WITH atrial fibrillation (ortholog); genetic disease (ortholog); male infertility (ortholog); FOUND IN 9+2 motile cilium (inferred); axoneme (inferred); cilium (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dynein heavy chain 10, axonemal
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210131,837,249 - 132,011,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112131,833,626 - 132,008,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012121,347,148 - 121,521,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112125,572,592 - 125,745,162 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12125,572,597 - 125,744,919 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNAH10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210131,837,249 - 132,011,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112131,833,626 - 132,008,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012121,347,148 - 121,521,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112125,572,592 - 125,745,162 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12125,572,597 - 125,744,919 (+)Ensemblpanpan1.1panPan2
DNAH10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812123,762,301 - 123,935,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12123,762,188 - 123,935,720 (+)EnsemblGRCh38hg38GRCh38
GRCh3712124,246,848 - 124,420,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612122,812,995 - 122,986,220 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412122,844,865 - 122,891,664NCBI
Celera12123,843,433 - 124,020,043 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12121,208,231 - 121,382,405 (+)NCBIHuRef
CHM1_112124,067,935 - 124,240,960 (+)NCBICHM1_1
T2T-CHM13v2.012123,761,225 - 123,937,157 (+)NCBIT2T-CHM13v2.0
Dnah10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395124,802,149 - 124,911,372 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5124,802,149 - 124,911,372 (+)EnsemblGRCm39 Ensembl
GRCm385124,725,085 - 124,834,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5124,725,085 - 124,834,308 (+)EnsemblGRCm38mm10GRCm38
MGSCv375125,205,455 - 125,314,678 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365125,020,414 - 125,123,287 (+)NCBIMGSCv36mm8
Celera5121,738,440 - 121,847,785 (+)NCBICelera
Cytogenetic Map5F- G1.1NCBI
cM Map563.78NCBI
Dnah10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81237,484,444 - 37,607,810 (-)NCBIGRCr8
mRatBN7.21231,823,451 - 31,946,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1231,822,733 - 32,007,069 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01237,237,482 - 37,365,258 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01239,111,938 - 39,235,342 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,925,061 - 33,058,479 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11232,859,312 - 32,864,220 (-)NCBI
Celera1233,514,289 - 33,636,977 (-)NCBICelera
Cytogenetic Map12q15NCBI
Dnah10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554825,206,847 - 5,308,218 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554825,206,653 - 5,308,437 (-)NCBIChiLan1.0ChiLan1.0
DNAH10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1265,774,692 - 5,906,706 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl265,866,925 - 5,896,185 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha265,937,911 - 6,069,540 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0266,024,999 - 6,156,726 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1265,958,664 - 6,090,249 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,050,991 - 6,182,608 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,003,953 - 6,135,803 (-)NCBIUU_Cfam_GSD_1.0
Dnah10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118158,375,162 - 158,495,433 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936558984,226 - 1,104,135 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936558984,105 - 1,104,390 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1429,095,490 - 29,249,833 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11429,095,480 - 29,250,255 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21430,793,005 - 30,942,600 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111119,098,664 - 119,273,913 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11119,105,264 - 119,273,675 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037125,999,855 - 126,177,298 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnah10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474723,504,219 - 23,602,434 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474723,504,187 - 23,602,565 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008964478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000031599   ⟹   ENSPPAP00000008959
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12125,572,597 - 125,744,919 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000031614   ⟹   ENSPPAP00000008974
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12125,591,724 - 125,624,231 (+)Ensembl
RefSeq Acc Id: XM_008964478   ⟹   XP_008962726
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210131,837,249 - 132,011,810 (+)NCBI
NHGRI_mPanPan112131,833,626 - 132,008,245 (+)NCBI
Mhudiblu_PPA_v012121,347,148 - 121,521,686 (+)NCBI
PanPan1.112125,572,592 - 125,745,162 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008962726 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008959.1
  ENSPPAP00000008974.1
RefSeq Acc Id: XP_008962726   ⟸   XM_008964478
- UniProtKB: A0A2R8ZVH3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000008959   ⟸   ENSPPAT00000031599
Ensembl Acc Id: ENSPPAP00000008974   ⟸   ENSPPAT00000031614
Protein Domains
AAA+ ATPase   Dynein heavy chain tail


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027673 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031599.1 UniProtKB/TrEMBL
  ENSPPAT00000031614.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2620 UniProtKB/TrEMBL
  1.10.472.130 UniProtKB/TrEMBL
  1.10.8.1220 UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_6 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_fam UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/TrEMBL
  Dynein_heavy_linker UniProtKB/TrEMBL
  Dynein_heavy_tail UniProtKB/TrEMBL
  Dynein_linker_3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene DNAH10 ENTREZGENE
PANTHER DYNEIN AXONEMAL HEAVY CHAIN 10 UniProtKB/TrEMBL
  DYNEIN HEAVY CHAIN FAMILY PROTEIN UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/TrEMBL
  AAA_7 UniProtKB/TrEMBL
  AAA_8 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_1 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  DHC_N1 UniProtKB/TrEMBL
  DHC_N2 UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/TrEMBL
  PF12777 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZVH3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZVI9_PANPA UniProtKB/TrEMBL