PBX4 (PBX homeobox 4) - Rat Genome Database

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Gene: PBX4 (PBX homeobox 4) Pan paniscus
Analyze
Symbol: PBX4
Name: PBX homeobox 4
RGD ID: 12030159
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); sequence-specific DNA binding (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); FOUND IN nucleus (inferred); XY body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103785966; pre-B-cell leukemia transcription factor 4; uncharacterized LOC103785966
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22024,424,072 - 24,484,677 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11923,430,504 - 23,491,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01919,000,136 - 19,056,959 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,997,736 - 20,052,420 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,998,049 - 20,052,444 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)
XY body  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PBX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22024,424,072 - 24,484,677 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11923,430,504 - 23,491,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01919,000,136 - 19,056,959 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,997,736 - 20,052,420 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,998,049 - 20,052,444 (-)Ensemblpanpan1.1panPan2
PBX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381919,561,713 - 19,618,687 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1919,561,707 - 19,618,693 (-)EnsemblGRCh38hg38GRCh38
GRCh371919,672,522 - 19,729,496 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,533,522 - 19,590,439 (-)NCBINCBI36Build 36hg18NCBI36
Build 341919,533,523 - 19,590,439NCBI
Celera1919,576,585 - 19,633,514 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1919,234,724 - 19,292,030 (-)NCBIHuRef
CHM1_11919,673,416 - 19,730,811 (-)NCBICHM1_1
T2T-CHM13v2.01919,699,203 - 19,756,196 (-)NCBIT2T-CHM13v2.0
Pbx4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,285,127 - 70,324,942 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,285,141 - 70,324,942 (+)EnsemblGRCm39 Ensembl
GRCm38869,832,476 - 69,872,292 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,832,491 - 69,872,292 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,356,603 - 72,396,191 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36872,761,693 - 72,801,281 (+)NCBIMGSCv36mm8
Celera872,383,673 - 72,431,127 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.92NCBI
Pbx4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,588,998 - 19,624,016 (-)NCBIGRCr8
mRatBN7.21619,555,089 - 19,590,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,555,090 - 19,590,014 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,596,110 - 19,631,891 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,734,081 - 20,769,843 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,649,091 - 19,684,872 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01621,303,117 - 21,338,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,303,837 - 21,338,771 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01621,219,201 - 21,253,490 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41620,039,883 - 20,074,963 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11620,039,879 - 20,074,937 (-)NCBI
Celera1619,744,197 - 19,779,088 (-)NCBICelera
Cytogenetic Map16p14NCBI
PBX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12043,653,532 - 43,687,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2043,653,447 - 43,687,843 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2043,569,163 - 43,605,696 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,139,267 - 44,176,323 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,139,267 - 44,176,292 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,376,916 - 43,413,939 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02043,786,639 - 43,823,161 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,062,156 - 44,098,960 (+)NCBIUU_Cfam_GSD_1.0
Pbx4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,330,003 - 202,362,183 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365961,879,198 - 1,908,483 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365961,879,198 - 1,911,336 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PBX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,304,081 - 58,363,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,303,066 - 58,363,919 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,334,087 - 58,392,766 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PBX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1618,022,925 - 18,078,184 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl618,023,232 - 18,032,069 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,221,047 - 1,279,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000048349   ⟹   ENSPPAP00000025522
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1919,998,049 - 20,052,444 (-)Ensembl
RefSeq Acc Id: XM_008970975   ⟹   XP_008969223
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22024,424,072 - 24,484,677 (-)NCBI
NHGRI_mPanPan11923,430,504 - 23,491,137 (-)NCBI
Mhudiblu_PPA_v01919,000,136 - 19,056,955 (-)NCBI
PanPan1.11919,997,736 - 20,052,420 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008969223 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025522.1
RefSeq Acc Id: XP_008969223   ⟸   XM_008970975
- UniProtKB: A0A2R9B7F2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000025522   ⟸   ENSPPAT00000048349
Protein Domains
Homeobox   PBC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035891 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048349.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  PBX UniProtKB/TrEMBL
  TALE_homeobox UniProtKB/TrEMBL
NCBI Gene PBX4 ENTREZGENE
PANTHER HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
  PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR 4 UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
  PBC UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A2R9B7F2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 PBX4  PBX homeobox 4  LOC103785966  uncharacterized LOC103785966  Data merged from RGD:11806479 737654 PROVISIONAL