HBS1L (HBS1 like translational GTPase) - Rat Genome Database

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Gene: HBS1L (HBS1 like translational GTPase) Pan paniscus
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Symbol: HBS1L
Name: HBS1 like translational GTPase
RGD ID: 12021254
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); translation elongation factor activity (inferred); INVOLVED IN nuclear-transcribed mRNA catabolic process, no-go decay (inferred); regulation of translation (inferred); rescue of stalled ribosome (inferred); PARTICIPATES IN translation termination pathway; ASSOCIATED WITH beta thalassemia (ortholog); Familial Behcet-Like Autoinflammatory Syndrome (ortholog); FOUND IN cytosolic ribosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25154,942,160 - 155,032,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16152,847,754 - 152,938,090 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06132,732,351 - 132,826,210 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16136,832,884 - 136,922,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6136,832,884 - 136,922,957 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HBS1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25154,942,160 - 155,032,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16152,847,754 - 152,938,090 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06132,732,351 - 132,826,210 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16136,832,884 - 136,922,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6136,832,884 - 136,922,957 (-)Ensemblpanpan1.1panPan2
HBS1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386134,960,378 - 135,054,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6134,960,378 - 135,103,056 (-)EnsemblGRCh38hg38GRCh38
GRCh376135,281,516 - 135,375,960 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,323,209 - 135,417,715 (-)NCBINCBI36Build 36hg18NCBI36
Build 346135,323,215 - 135,417,715NCBI
Celera6136,021,872 - 136,116,411 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6132,845,729 - 132,940,277 (-)NCBIHuRef
CHM1_16135,543,237 - 135,637,724 (-)NCBICHM1_1
T2T-CHM13v2.06136,148,628 - 136,243,073 (-)NCBIT2T-CHM13v2.0
Hbs1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391021,171,876 - 21,244,788 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1021,171,878 - 21,244,797 (+)EnsemblGRCm39 Ensembl
GRCm381021,295,979 - 21,368,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1021,295,979 - 21,368,898 (+)EnsemblGRCm38mm10GRCm38
MGSCv371021,015,785 - 21,088,695 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361020,996,767 - 21,058,314 (+)NCBIMGSCv36mm8
Celera1021,189,454 - 21,263,423 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map109.75NCBI
Hbs1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8117,912,139 - 17,989,651 (+)NCBIGRCr8
mRatBN7.2116,092,529 - 16,170,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,092,547 - 16,170,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,848,285 - 15,925,916 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,850,176 - 21,927,805 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,073,502 - 16,151,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,819,170 - 16,896,234 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,819,170 - 16,896,219 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,974,876 - 18,051,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,668,214 - 16,736,914 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1116,668,273 - 16,736,974 (+)NCBI
Celera114,510,728 - 14,588,123 (+)NCBICelera
Cytogenetic Map1p12NCBI
Hbs1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,683,685 - 1,762,314 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,684,466 - 1,762,314 (+)NCBIChiLan1.0ChiLan1.0
HBS1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,704,375 - 27,791,376 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,695,441 - 27,791,381 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,584,758 - 28,671,733 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0127,861,829 - 27,948,018 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl127,860,024 - 27,947,992 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1127,746,364 - 27,833,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,626,482 - 27,713,519 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0127,937,668 - 28,024,033 (-)NCBIUU_Cfam_GSD_1.0
Hbs1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946122,812,710 - 122,900,212 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365602,591,821 - 2,679,428 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365602,591,925 - 2,679,436 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HBS1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl129,018,351 - 29,052,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1128,968,778 - 29,052,427 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,459,545 - 32,530,004 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HBS1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11338,383,405 - 38,478,569 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1338,383,435 - 38,473,429 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604010,581,023 - 10,677,947 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hbs1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248862,605,364 - 2,691,705 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248862,606,072 - 2,691,323 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000036411   ⟹   ENSPPAP00000013737
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,832,884 - 136,922,957 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036414   ⟹   ENSPPAP00000013740
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,832,884 - 136,922,957 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036423   ⟹   ENSPPAP00000013749
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,834,435 - 136,922,750 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036426   ⟹   ENSPPAP00000013752
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,834,435 - 136,922,750 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036432   ⟹   ENSPPAP00000013758
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,903,980 - 136,922,957 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000036433   ⟹   ENSPPAP00000013759
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6136,906,026 - 136,922,750 (-)Ensembl
RefSeq Acc Id: XM_003827682   ⟹   XP_003827730
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,942,160 - 155,032,510 (-)NCBI
NHGRI_mPanPan16152,847,754 - 152,938,090 (-)NCBI
Mhudiblu_PPA_v06132,732,351 - 132,826,202 (-)NCBI
PanPan1.16136,832,884 - 136,922,957 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953029   ⟹   XP_008951277
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,995,414 - 155,032,501 (-)NCBI
NHGRI_mPanPan16152,910,081 - 152,938,081 (-)NCBI
Mhudiblu_PPA_v06132,807,850 - 132,826,210 (-)NCBI
PanPan1.16136,903,980 - 136,922,957 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034962881   ⟹   XP_034818772
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,942,160 - 155,032,442 (-)NCBI
NHGRI_mPanPan16152,847,754 - 152,938,015 (-)NCBI
Mhudiblu_PPA_v06132,735,884 - 132,826,175 (-)NCBI
RefSeq Acc Id: XM_034962882   ⟹   XP_034818773
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,943,855 - 155,032,485 (-)NCBI
NHGRI_mPanPan16152,849,449 - 152,938,065 (-)NCBI
Mhudiblu_PPA_v06132,737,579 - 132,826,176 (-)NCBI
RefSeq Acc Id: XM_034962884   ⟹   XP_034818775
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,942,160 - 155,005,063 (-)NCBI
NHGRI_mPanPan16152,847,754 - 152,910,658 (-)NCBI
Mhudiblu_PPA_v06132,735,884 - 132,798,517 (-)NCBI
RefSeq Acc Id: XM_055114139   ⟹   XP_054970114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25154,942,160 - 155,015,473 (-)NCBI
NHGRI_mPanPan16152,847,754 - 152,921,061 (-)NCBI
RefSeq Acc Id: XP_003827730   ⟸   XM_003827682
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AE88 (UniProtKB/TrEMBL),   A0A2R9A903 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951277   ⟸   XM_008953029
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AE12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034818772   ⟸   XM_034962881
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034818775   ⟸   XM_034962884
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AE96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034818773   ⟸   XM_034962882
- Peptide Label: isoform X4
- UniProtKB: A0A2R9A903 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000013737   ⟸   ENSPPAT00000036411
Ensembl Acc Id: ENSPPAP00000013740   ⟸   ENSPPAT00000036414
Ensembl Acc Id: ENSPPAP00000013759   ⟸   ENSPPAT00000036433
Ensembl Acc Id: ENSPPAP00000013758   ⟸   ENSPPAT00000036432
Ensembl Acc Id: ENSPPAP00000013752   ⟸   ENSPPAT00000036426
Ensembl Acc Id: ENSPPAP00000013749   ⟸   ENSPPAT00000036423
RefSeq Acc Id: XP_054970114   ⟸   XM_055114139
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AE96 (UniProtKB/TrEMBL)
Protein Domains
HBS1-like protein N-terminal   tr-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029900 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036411.1 UniProtKB/TrEMBL
  ENSPPAT00000036414.1 UniProtKB/TrEMBL
  ENSPPAT00000036423.1 UniProtKB/TrEMBL
  ENSPPAT00000036426.1 UniProtKB/TrEMBL
  ENSPPAT00000036432.1 UniProtKB/TrEMBL
  ENSPPAT00000036433.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
InterPro EFTu-like_2 UniProtKB/TrEMBL
  GTP-eEF1A_C UniProtKB/TrEMBL
  HBS1-like_N UniProtKB/TrEMBL
  HBS1-like_N_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL
  TRAFAC_GTPase_members UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
  Transl_elong_EF1A/Init_IF2_C UniProtKB/TrEMBL
KEGG Report pps:100986512 UniProtKB/TrEMBL
NCBI Gene HBS1L ENTREZGENE
PANTHER HBS1-LIKE PROTEIN UniProtKB/TrEMBL
  TRANSLATION FACTOR UniProtKB/TrEMBL
Pfam GTP-eEF1A_C UniProtKB/TrEMBL
  GTP_EFTU UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/TrEMBL
  HBS1_N UniProtKB/TrEMBL
PRINTS ELONGATNFCT UniProtKB/TrEMBL
PROSITE G_TR_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109732 UniProtKB/TrEMBL
  SSF50447 UniProtKB/TrEMBL
  SSF50465 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9A8Z6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A903 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A913_PANPA UniProtKB/TrEMBL
  A0A2R9AE12 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AE88 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AE96 ENTREZGENE, UniProtKB/TrEMBL