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Gene: MAGEF1 (MAGE family member F1) Pan paniscus

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Symbol:

MAGEF1

Name:

MAGE family member F1

RGD ID:

11962430

Description:

INVOLVED IN negative regulation of double-strand break repair via homologous recombination (inferred); negative regulation of transcription by RNA polymerase II (inferred); positive regulation of ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH Currarino syndrome (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

melanoma-associated antigen F1

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAGEF1 (MAGE family member F1)	NCBI	Ortholog
Mus musculus (house mouse):	Magef1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Magef1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAGEF1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Magef1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAGEF1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAGEF1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Magef1 (MAGE family member F1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	182,586,198 - 182,588,000 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	182,590,914 - 182,592,631 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	181,750,186 - 181,751,900 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	190,229,331 - 190,231,092 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	190,229,865 - 190,230,791 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Currarino syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of double-strand break repair via homologous recombination (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

positive regulation of ubiquitin-dependent protein catabolic process (IEA)

protein maturation by iron-sulfur cluster transfer (IEA)

protein ubiquitination (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

MAGEF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	182,586,198 - 182,588,000 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	182,590,914 - 182,592,631 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	181,750,186 - 181,751,900 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	190,229,331 - 190,231,092 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	190,229,865 - 190,230,791 (-)	Ensembl	panpan1.1		panPan2

MAGEF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	184,710,364 - 184,712,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	184,710,364 - 184,712,064 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	184,428,152 - 184,429,852 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	185,910,849 - 185,912,530 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	185,910,857 - 185,912,538	NCBI
Celera	3	182,876,192 - 182,877,873 (-)	NCBI		Celera
Cytogenetic Map	3	q27.1	NCBI
HuRef	3	181,838,998 - 181,840,682 (-)	NCBI		HuRef
CHM1_1	3	184,391,819 - 184,393,503 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	187,525,551 - 187,527,254 (-)	NCBI		T2T-CHM13v2.0

Magef1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	21,150,650 - 21,152,106 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	21,151,396 - 21,151,879 (-)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	16	21,140,249 - 21,152,139 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	21,331,900 - 21,333,356 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	21,331,902 - 21,333,356 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	21,331,975 - 21,333,423 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	21,245,885 - 21,247,333 (-)	NCBI		MGSCv36	mm8
Celera	16	21,898,255 - 21,900,033 (-)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI

Magef1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955420	22,797,581 - 22,799,301 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAGEF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	17,543,381 - 17,545,089 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	17,543,906 - 17,544,868 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	21,629,348 - 21,631,035 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	17,451,958 - 17,453,649 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	17,451,962 - 17,453,690 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	17,488,532 - 17,490,223 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	17,484,325 - 17,486,022 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	17,713,119 - 17,714,816 (-)	NCBI		UU_Cfam_GSD_1.0

Magef1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	119,086,513 - 119,088,202 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	5,178,609 - 5,179,547 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	5,178,399 - 5,180,058 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAGEF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	122,598,928 - 122,602,646 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	122,600,984 - 122,602,700 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	132,132,372 - 132,134,049 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAGEF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	4,706,254 - 4,707,932 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	4,706,476 - 4,707,402 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	13,474,058 - 13,475,812 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Magef1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	71,862,531 - 71,865,328 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003806600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000025405 ⟹ ENSPPAP00000005611

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	190,229,865 - 190,230,791 (-)	Ensembl

RefSeq Acc Id:

XM_003806600 ⟹ XP_003806648

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	182,586,198 - 182,588,000 (-)	NCBI
NHGRI_mPanPan1	3	182,590,914 - 182,592,631 (-)	NCBI
Mhudiblu_PPA_v0	3	181,750,186 - 181,751,900 (-)	NCBI
PanPan1.1	3	190,229,331 - 190,231,092 (-)	NCBI

Sequence:

show sequence

GACCGGAAAAGGAGGGGCTGCGCCCGGCACTAGGGTCGCCATCCTGGCTGAGGTGGCCGGAAAT
GGCCCCTCGCGCGGGCGCGGACTGAGGCTGCGCGCCGCAGGTTCCGGCTGCTGGCGGCGTTGCG
GCCGCAGGTTTGACTCCCGTGCGGTGCCGCCCAGCAGCCACAAAGCTCCCGCTGCCATTGCTCC
TCGTACTCCCGCCGCCACTGCCGCTGTCCAACCCCTCCCCCGGGGCTTGCGCGGCGGCTCCCAC
ACCCCTCGGCCCGTGTACGCGCTCTGCACCTGCCTGCCCGAAAACATGTTGCAGACACCAGAGA
GCGGGGGGCTCCCGGTCCCGCAGGCCGAGGGGGAGAAGGATGGCGGCCATGATGGTGAGACCCG
GGCCCCGACCGCCTCGCAGGAGCGCCCCAAGGAGGAGCTTGGCGCCGGGAGGGAGGAGGGGGCT
GCGGAACCCGCCCTCACCCGGAAAGGCGCGAGGGCCTTGGCGGCCAAAGCCTTGGCAAGGCGCA
GGGCCTACCGCCGTCTGAATCGGACGGTGGCGGAGTTGGTGCAGTTCCTCCTGGTGAAAGACAA
GAAGAAGAGTCCCATCACACGCTCGGAGATGGTGAAATACGTTATTGGAGACTTGAAGATTCTG
TTCCCGGACATCATCGCAAGGGCCGCAGAGCATCTGCGGTATGTCTTTGGTTTTGAGCTGAAAC
AGTTTGACCGCAAGCACCACACTTACATCCTGATCAACAAACTAAAACCTCTGGAGGAGGAGGA
GGAGGAGGAGGATCTGGGAGGAGATGGCCCCAGATTGGGTCTGTTAATGATGATCCTGGGCCTT
ATCTATATGAGAGGTAATAGCGCCAGGGAGGCCCAGGTCTGGGAGATGCTGCGTCGGTTGGGGG
TGCAACCCTCAAAGTATCATTTCCTCTTTGGGTATCCGAAGAGGCTTATTATGGAAGATTTTGT
GCAGCAGCGATATCTCAGTTACAGGCGGGTGCCTCACACCAATCCACCGGAATATGAATTCTCT
TGGGGTCCCCGAAGCCACCTGGAAATCAGCAAGATGAAAGTCCTGGGGTTCGTGGCCAAACTGC
ATAAGAAGGAACCGCAGCACTGGCCAGTGCAGTACCGTGAGGCCCTAGCAGACGAGGCCGACAG
GGCCAGAGCCAAGGCCAGAGCTGAAGCCAGTATGAGGGCCAGGGCCAGTGCTAGGGCCGGCATC
CACCTCTGGTGAGGGTTGGTGAAAAGTTGGCCAGTGGGTCCCCGTGAGGACGAGCTACTGTCCT
GAGTCATAAGTAATATGGGTGGGGCGAGGGTCTTATTTCTGTAGAAATCGTGTGACTTTAAGGA
TTTAGATTTTGTATCTTATGTTTTGTAACGTTTAATAATTACTGTTAAAATGCTGTTTGTAAAT
GAGATTGGTCTACTTTTTCCTGTAGGATTTTATTGTAGAGTTTTGCTGGTTTTGTAAAATGGAT
TGAAGAACTTTGTATTTATACTGTGATTTTGAACAGATTATGCAACATTGGAAGGAAGGCTGTA
CTTTGATGGGTTGAAGGAACTCAGCAGTATGATGATCTCGTTCCAGGGGAAAAAAACAGCTGGT
TGGTGTCTAGCCCCCCAACACTTTTGTCTGTTGTGTATAAAAGAAGAAAGACTGGCATGTACCT
CCATTTGCTTAGCTATTTGAGTATCTAGAGAAAAATTAAAATGCAATGAGTTAGCAGCATACCC
TGGCACACTTAATAAATTAAACATTTGTGGAGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003806648	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000005611
	ENSPPAP00000005611.1

RefSeq Acc Id:

XP_003806648 ⟸ XM_003806600

- UniProtKB:

A0A2R8ZRZ5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLQTPESGGLPVPQAEGEKDGGHDGETRAPTASQERPKEELGAGREEGAAEPALTRKGARALAA
KALARRRAYRRLNRTVAELVQFLLVKDKKKSPITRSEMVKYVIGDLKILFPDIIARAAEHLRYV
FGFELKQFDRKHHTYILINKLKPLEEEEEEEDLGGDGPRLGLLMMILGLIYMRGNSAREAQVWE
MLRRLGVQPSKYHFLFGYPKRLIMEDFVQQRYLSYRRVPHTNPPEYEFSWGPRSHLEISKMKVL
GFVAKLHKKEPQHWPVQYREALADEADRARAKARAEASMRARASARAGIHLW

hide sequence

Ensembl Acc Id:

ENSPPAP00000005611 ⟸ ENSPPAT00000025405

Protein Domains

MAGE

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000023136	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000025405.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.1200	UniProtKB/TrEMBL
	1.10.10.1210	UniProtKB/TrEMBL
InterPro	MAGE	UniProtKB/TrEMBL
	MAGE_WH1	UniProtKB/TrEMBL
	MAGE_WH2	UniProtKB/TrEMBL
	MHD_dom	UniProtKB/TrEMBL
KEGG Report	pps:100983122	UniProtKB/TrEMBL
NCBI Gene	MAGEF1	ENTREZGENE
PANTHER	MELANOMA-ASSOCIATED ANTIGEN F1	UniProtKB/TrEMBL
	PTHR11736	UniProtKB/TrEMBL
Pfam	MAGE	UniProtKB/TrEMBL
PROSITE	MAGE	UniProtKB/TrEMBL
SMART	MAGE	UniProtKB/TrEMBL
UniProt	A0A2R8ZRZ5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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